Results 31 to 40 of about 19,422 (160)

Data on the evaluation of the relation between β-arrestin 2 and YAP phosphorylation in patient-derived colon cancer organoids

Data in Brief, 2022
The data presented in this article is related to a rapid communication entitled “β-arrestin 2 suppresses the activation of YAP by promoting LATS kinase activity”.
Minsuh Kim, Ji Min Kim, Eun Jeong Cho, Chang Ohk Sung, Joon Kim, Se Jin Jang   +5 more
doaj   +1 more source

β-Arrestin regulation of myosin light chain phosphorylation promotes AT1aR-mediated cell contraction and migration. [PDF]

PLoS ONE, 2013
Over the last decade, it has been established that G-protein-coupled receptors (GPCRs) signal not only through canonical G-protein-mediated mechanisms, but also through the ubiquitous cellular scaffolds β-arrestin-1 and β-arrestin-2.
Elie Simard, Jeffrey J Kovacs, William E Miller, Jihee Kim, Michel Grandbois, Robert J Lefkowitz   +5 more
doaj   +1 more source

Surfactant protein-A modulates LPS-induced TLR4 localization and signaling via β-arrestin 2. [PDF]

PLoS ONE, 2013
The soluble C-type lectin surfactant protein (SP)-A mediates lung immune responses partially via its direct effects on alveolar macrophages (AM), the main resident leukocytes exposed to antigens. SP-A modulates the AM threshold of lipopolysaccharide (LPS)
Vicky Sender, Linda Lang, Cordula Stamme
doaj   +1 more source

Beta-Arrestins in the Treatment of Heart Failure Related to Hypertension: A Comprehensive Review

Pharmaceutics, 2021
Heart failure (HF) is a complicated clinical syndrome that is considered an increasingly frequent reason for hospitalization, characterized by a complex therapeutic regimen, reduced quality of life, and high morbidity.
Ahmed Rakib, Taslima Akter Eva, Saad Ahmed Sami, Saikat Mitra, Iqbal Hossain Nafiz, Ayan Das, Abu Montakim Tareq, Firzan Nainu, Kuldeep Dhama, Talha Bin Emran, Jesus Simal-Gandara   +10 more
doaj   +1 more source

A method for biomarker measurements in peripheral blood mononuclear cells isolated from anxious and depressed mice: β-arrestin 1 protein levels in depression and treatment

Frontiers in Pharmacology, 2013
A limited number of biomarkers in the central and peripheral systems which are known may be useful for diagnosing major depressive disorders and predicting the effectiveness of antidepressant treatments.
Indira eMENDEZ-DAVID, Zeina eEL-ALI, Rene eHEN, Bruno eFALISSARD, Emmanuelle eCORRUBLE, Alain M GARDIER, Saadia eKERDINE-ROMER, Denis Joseph DAVID   +7 more
doaj   +1 more source

Endothelial β‐arrestins regulate mechanotransduction by the type II bone morphogenetic protein receptor in primary cilia

Pulmonary Circulation, 2022
Modulation of endothelial cell behavior and phenotype by hemodynamic forces involves many signaling components, including cell surface receptors, intracellular signaling intermediaries, transcription factors, and epigenetic elements.
Saejeong Park, Zhiyuan Ma, Georgia Zarkada, Irinna Papangeli, Sarin Paluri, Nour Nazo, Felix Rivera‐Molina, Derek Toomre, Sudarshan Rajagopal, Hyung J. Chun   +9 more
doaj   +1 more source

B-arrestin-2 Signaling Is Important to Preserve Cardiac Function During Aging

Frontiers in Physiology, 2021
Experiments reported here tested the hypothesis that β-arrestin-2 is an important element in the preservation of cardiac function during aging. We tested this hypothesis by aging β-arrestin-2 knock-out (KO) mice, and wild-type equivalent (WT) to 12 ...
Andrielle E. Capote, Ashley Batra, Chad M. Warren, Shamim A. K. Chowdhury, Beata M. Wolska, Beata M. Wolska, R. John Solaro, Paola C. Rosas   +7 more
doaj   +1 more source

Phosphorylation of β-arrestin2 at Thr383 by MEK underlies β-arrestin-dependent activation of Erk1/2 by GPCRs

eLife, 2017
In addition to their role in desensitization and internalization of G protein-coupled receptors (GPCRs), β-arrestins are essential scaffolds linking GPCRs to Erk1/2 signaling.
Elisabeth Cassier, Nathalie Gallay, Thomas Bourquard, Sylvie Claeysen, Joël Bockaert, Pascale Crépieux, Anne Poupon, Eric Reiter, Philippe Marin, Franck Vandermoere   +9 more
doaj   +1 more source

The Clinical Significance of β-arrestin 2 Expression in the Serum of 
Non-small Cell Lung Cancer Patients

Chinese Journal of Lung Cancer, 2011
Background and objective Non-small cell lung cancer (NSCLC) with high morbidity and mortality is the most common types of lung cancer. beta-arrestin 2 is a kind of soluble protein regulating signal transduction mediated by G protein coupling receptor ...
Zhengqing WU, Wenxia TONG, Zihui TAN, Siyu WANG, Peng LIN   +4 more
doaj   +1 more source

Ezrin, Radixin, and Moesin Phosphorylation in NIH3T3 Cells Revealed Angiotensin II Type 1 Receptor Cell-Type–Dependent Biased Signaling

Journal of Pharmacological Sciences, 2013
.: β-Arrestin-biased agonists are a new class of drugs with promising therapeutic effects. The molecular mechanisms of β-arrestin-biased agonists are still not completely identified.
Islam A.A.E-H. Ibrahim, Michio Nakaya, Hitoshi Kurose   +2 more
doaj   +1 more source