Enhancement of Anti-Tumoral Immunity by β-Casomorphin-7 Inhibits Cancer Development and Metastasis of Colorectal Cancer [PDF]
International Journal of Molecular Sciences, 2021 Hitoshi Ohmori +2 more
exaly +2 more sources
Genetic Diversity of the Beta-Casein Gene in Brown Swiss and Creole Cattle From the Peruvian Highlands. [PDF]
Anim GenetABSTRACT Cattle's milk and derivatives are essential for human nutrition. However, up to 90% of people experience gastrointestinal discomfort after consumption. Milk digestibility depends on its protein composition. Casein, about 80% of milk proteins, includes beta‐casein (CSN2) with two variants: A1 and A2. The A1 variant is linked to gastrointestinal
Remigio Lorenzo LR +7 more
europepmc +2 more sources
Dairy, 2022 The drug-likeness and pharmacokinetic properties of 23 dairy-protein-derived opioid peptides were studied using SwissADME and ADMETlab in silico tools. All the opioid peptides had poor drug-like properties based on violations of Lipinski’s rule-of-five ...
Dawei Ji +6 more
doaj +1 more source
Effect of β-casomorphin-7 on intestinal mucosal immunity in aged mice [PDF]
Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019 The immune deficiency caused by aging deserves attention, especially the weakening of intestinal mucosal immunity. The effect of β-casomorphin-7 on intestinal mucosal immunity was investigated in aged mice.
Hong YIN +3 more
doaj +1 more source
Non-SELEX method for aptamer selection against β-casomorphin-7 peptide
Journal of Dairy Science, 2022 : The non-systematic evolution of ligands by the exponential enrichment (non-SELEX) method was used in the present study for the selection of β-casomorphin-7 (BCM-7)-specific aptamers.
Abhishek Parashar +4 more
doaj +1 more source
Identification of Polymorphisms of the CSN2 Gene Encoding β-Casein in Greek Local Breeds of Cattle
Veterinary Sciences, 2021 This e research focused on the detection and identification of genetic polymorphisms in exon 7 of the β-casein CSN2 gene in blood samples from Greek Holstein cows and from local breeds of cattle, such as Vrachykeratiki, Katerinis, and Sykias.
Dionysios Antonopoulos +7 more
doaj +1 more source
Use of allele specific PCR to investigate the presence of β-casein polymorphism in Holstein-Friesian cows [PDF]
Veterinarski Glasnik, 2022 Following the “one health” principle, we have conducted optimization of a protocol for β-casein genotyping in cattle in order to select cows with exclusively the A2A2 genotype.
Ristanić Marko +6 more
doaj +1 more source
Quantification of β-Casomorphin 7 in Commercially Available Filtered and Pasteurized Cow’s Milk
Biology and Life Sciences Forum, 2023 β-casomorphin 7 (BCM7) is a bioactive peptide that is released during the digestion of the β-casein (in particular, the A1 variant) present in cow’s milk. BCM7 has been linked to several health concerns such as gastrointestinal disorders. Milk processing
Raja Buatig +3 more
doaj +1 more source
Macronutrients as Regulators of Intestinal Epithelial Permeability: Where Do We Stand? [PDF]
Compr Rev Food Sci Food SafABSTRACT The intestinal barrier function (IBF) is essential for intestinal homeostasis. Its alterations have been linked to intestinal and systemic disease. Regulation of intestinal permeability is key in the maintenance of the IBF, in which the intestinal epithelium and tight junctions, the mucus layer, sIgA, and antimicrobial peptides are important ...
Martínez-Augustin O +9 more
europepmc +2 more sources
A2 Milk: New Perspectives for Food Technology and Human Health
Foods, 2022 Although milk consumption is increasing worldwide, in some geographical regions, its consumption has persistently declined in recent decades. This fact, together with the increase in milk production prices, has caused both milk producers and the dairy ...
Salvador Fernández-Rico +8 more
doaj +1 more source