Difficulties in Establishing the Adverse Effects of β-Casomorphin-7 Released from β-Casein Variants—A Review [PDF]
Foods, 2023 β-Casomorphin-7 (BCM-7) is a peptide released through the proteolysis of β-casein (β-CN), which is considered a bioactive peptide displaying evidence of promoting the binding and activation of the μ-opioid receptor located in various body parts, such as ...
Marta Liliane de Vasconcelos +2 more
exaly +5 more sources
Significance of CD10 for Mucosal Immunomodulation by β-Casomorphin-7 in Exacerbation of Ulcerative Colitis [PDF]
Current Issues in Molecular Biologyβ-Casomorphin-7 (BCM), a breakdown product of milk β-casein, exhibits opioid activity. Opioids are known to affect the immune system, but the effects of BCM on ulcerative colitis (UC) are not clear.
Yoshihiro Miyagawa +9 more
doaj +3 more sources
Effects of A1 Milk, A2 Milk and the Opioid-like Peptide β-Casomorphin-7 on the Proliferation of Human Peripheral Blood Mononuclear Cells [PDF]
BiomoleculesSpecial attention is given to cow’s milk and its variants, with ongoing discussions about health-related impacts primarily focusing on the A1 variant in contrast to the A2 variant.
Felix Gard +4 more
doaj +3 more sources
Quantification of β-Casomorphin 7 in Commercially Available Filtered and Pasteurized Cow’s Milk [PDF]
Biology and Life Sciences Forum, 2023 β-casomorphin 7 (BCM7) is a bioactive peptide that is released during the digestion of the β-casein (in particular, the A1 variant) present in cow’s milk. BCM7 has been linked to several health concerns such as gastrointestinal disorders. Milk processing
Raja Buatig +3 more
doaj +3 more sources
β-Casomorphin-7 as a Potential Inflammatory Marker: How β-Casomorphin-7 Induces Endothelial Dysfunction in HUVEC/TERT2 Cell Lines [PDF]
BiomedicinesBackground/Objectives: Endothelial dysfunction plays a central role in the development of cardiovascular diseases. β-Casomorphin-7 (BCM-7), a biologically active peptide generated during the digestion of A1 β-casein, is presumed to contribute to this ...
Judit Rita Homoki +10 more
doaj +2 more sources
Comparative Effects of Milk Containing A1 versus A2 β-Casein on Health, Growth and β-Casomorphin-7 Level in Plasma of Neonatal Dairy Calves [PDF]
Animals, 2020 Research has shown that digestion of A1 β-casein (β-CN) affects gastrointestinal motility and opioid activity through the release of the peptide β-casomorphin-7 (β-CM7).
Lisa G. Hohmann +5 more
doaj +2 more sources
β-casomorphin-7: a review of occurrence, identification, techno-functionality, and effects on human health [PDF]
npj Science of Foodβ-casomorphin-7 (βCM-7) is a bioactive peptide released after the digestion of β-casein A1 variant, mostly found in European cow breeds’ milk. This review explores the occurrence, characteristics, identification, techno-functionality, and the potential ...
Abdelmoneim H. Ali +5 more
doaj +2 more sources
Differential Release of β-Casomorphins from A1 and A2 Milk During Standardized Gastrointestinal Digestion Quantified by CE–MS [PDF]
Foodsβ-Casein A1 and A2 (β-CN-A1 and β-CN-A2) are the two predominant β-CN proteoforms in bovine milk. β-CN-A1 has been associated with a greater propensity to release opioid peptides, such as β-casomorphin-7 (β-CM-7) and β-casomorphin-5 (β-CM-5), during ...
Tahereh Tehrani +5 more
doaj +2 more sources
Influence of the β-Casein Genotype of Cow’s Milk (A1, A2) on the Quality and β-Casomorphin-7 (BCM-7) Content of a Semi-Hard Cheese During Production [PDF]
FoodsCow’s milk contains A1- and A2-β-caseins. The breakdown of A1-β-casein produces β-casomorphin-7 (BCM-7), a peptide with opioid-like properties that is associated with health aspects.
Louisa Zinßius +5 more
doaj +2 more sources
The Characteristics of A1-A2 β-Caseins in Milk and Their Effects on Human Health
Turkish Journal of Agriculture: Food Science and Technology, 2021 Despite positive effects on nutrition, it has been reported that milk causes allergic reactions and many health problems. Allergic reaction to milk is called lactose intolerance, but it is estimated that this is not caused by lactose, but by the β ...
Sema Yaman Fırıncıoğlu +1 more
doaj +3 more sources