Results 1 to 10 of about 1,585,908 (347)

Oncogenic β-catenin mutations evade pH-regulated degradation

Molecular & Cellular Oncology, 2019
β-catenin has roles in cell-cell adhesion and Wnt signaling. We recently showed that β-catenin protein abundance is decreased at higher intracellular pH (pHi), mediated by pH-sensitive interaction with the beta-transducin repeat containing E3 ubiquitin ...
Bree K. Grillo-Hill, Katharine A. White
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Inhibiting β-Catenin by β-Carboline-Type MDM2 Inhibitor for Pancreatic Cancer Therapy

Frontiers in Pharmacology, 2018
The β-catenin and MDM2 oncoproteins are overexpressed and constitutively activated in human pancreatic cancer and contribute to its initiation, progression, and metastasis.
Jiang-Jiang Qin, Wei Wang, Wei Wang, Xin Li, Hemantkumar Deokar, John K. Buolamwini, Ruiwen Zhang, Ruiwen Zhang   +7 more
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Additional file 10: of Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma

, 2019
Table S3. Univariate and multivariate analyses of OS in 102 HCC patients by Cox regression analysis. (DOCX 14 kb)
Deng, Ling, Jingyuan Sun, Xiaohui Chen, Liu, Li, Dehua Wu   +4 more
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Additional file 5: of RNA helicase p68 deploys β-catenin in regulating RelA/p65 gene expression: implications in colon cancer

, 2019
Table S1. List of primers used in the study. (DOCX 19 kb)
Veenita Khare, Shaheda Tabassum, Uttara Chatterjee, Sandip Chatterjee, Ghosh, Mrinal   +4 more
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A transphyletic study of metazoan β-catenin protein complexes

Zoological Letters
Beta-catenin is essential for diverse biological processes, such as body axis determination and cell differentiation, during metazoan embryonic development.
Ivan Mbogo, Chihiro Kawano, Ryotaro Nakamura, Yuko Tsuchiya, Alejandro Villar-Briones, Yoshitoshi Hirao, Yuuri Yasuoka, Eisuke Hayakawa, Kentaro Tomii, Hiroshi Watanabe   +9 more
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siRNA-Mediated β-Catenin Knockdown in Human Hepatoma Cells Results in Decreased Growth and Survival

Neoplasia: An International Journal for Oncology Research, 2007
β-Catenin, the chief oncogenic component of the canonical Wnt pathway, is known to be involved in a variety of cancers, including hepatocellular carcinoma (HCC).
Gang Zeng, Udayan Apte, Benjamin Cieply, Sucha Singh, Satdarshan P.S. Monga   +4 more
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ICG-001, an Inhibitor of the β-Catenin and cAMP Response Element-Binding Protein Dependent Gene Transcription, Decreases Proliferation but Enhances Migration of Osteosarcoma Cells [PDF]

, 2021
Geoffroy Danieau, Sarah Morice, Sarah Renault, Régis Brion, Kévin Biteau, Jérôme Amiaud, Marie Cadé, Dominique Heymann, Frédéric Lézot, Franck Verrecchia, Françoise Rédiní, Bénédicte Brounais-Le Royer   +11 more
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Additional file 2: of The lncRNA NEAT1 activates Wnt/β-catenin signaling and promotes colorectal cancer progression via interacting with DDX5

, 2018
Table S1. Primary antibodies for western blot. Table S2. Primers for real-time PCR. Table S3. Association between clinicopathological features and NEAT1 expression. Table S4. Univariate Cox proportional hazards model for overall survival (OS) and disease-free survival (DFS). Table S5. Multivariate Cox proportional hazards model for OS and DFS.
Zhang, Meng, Weng, Weiwei, Zhang, Qiongyan, Wu, Yong, Ni, Shujuan, Tan, Cong, Xu, Midie, Sun, Hui, Liu, Chenchen, Wei, Ping, Du, Xiang   +10 more
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Additional file 1: Table S1. of Stress-inducible Protein-1 promotes metastasis of gastric cancer via Wnt/β-catenin signaling pathway

, 2018
Antibodies Used. (DOCX 17 kb)
Huang, Linlin, Zhai, Ertao, Cai, Shirong, Lin, Yi, Liao, Junbin, Jin, Huilin, Peng, Sui, Xu, Lixia, Chen, Minhu, Zeng, Zhirong   +9 more
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Additional file 7: of RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling pathway and EMT in colorectal cancer

, 2019
Table S3. Relationship between RUNX1 mRNA expression and the clinicpathological features of CRC patients. (DOCX 14 kb)
Li, Qingyuan, Lai, Qiuhua, He, Chengcheng, Fang, Yuxin, Yan, Qun, Zhang, Yue, Wang, Xinke, Gu, Chuncai, Wang, Yiqing, Ye, Liangying, Han, Lu, Lin, Xin, Chen, Junsheng, Cai, Jianqun, Li, Aimin, Liu, Side   +15 more
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