Results 101 to 110 of about 1,062,506 (300)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Additional file 5: of Aberrantly expressed miR-188-5p promotes gastric cancer metastasis by activating Wnt/β-catenin signaling

, 2019
Table S4. The sequences of primers used in real-time RT-PCR assay. (DOCX 14 kb)
Li, Yun, Yan, Xiaoli, Shi, Jiajian, He, Yun, Xu, Jie, Lin, Liying, Chen, Wannan, Lin, Xinjian, Lin, Xu   +8 more
openaire   +1 more source

β-catenin expression in perilesional area of different grades of oral squamous cell carcinoma [PDF]

, 2016
Objectives: Background: Multistep carcinogenesis discusses a stepwise accumulation of alterations, both genotypic and phenotypic. Arresting one or several of the steps may disturb or delay the development of cancer.
Marwa A. Hamied
core   +2 more sources

Table5_Global role of IGF2BP1 in controlling the expression of Wnt/β-catenin-regulated genes in colorectal cancer cells.xlsx

, 2023
Introduction: Wnt/β-catenin signaling controls cell division and lineage specification during embryonic development, and is crucial for stem cells maintenance and gut tissue regeneration in adults.
Irina Elcheva (3844003), Vonn Walter (165501), Vladimir S. Spiegelman (10308404), Yuka Imamura Kawasawa (7254923), Vikash Singh (387413)   +4 more
core   +1 more source

Patient‐Derived 3D Heart‐On‐a‐Chip Model of Dilated Cardiomyopathy With Embedded Bead‐Based Mapping of Tissue Contractility

Advanced Healthcare Materials, EarlyView.
A heart‐on‐a‐chip model of dilated cardiomyopathy is developed from patient‐derived induced pluripotent stem cells. The model recapitulates key disease phenotypes and enables functional assessment through integrated bead‐based tracking and pillar deflection measurements.
Ali Mousavi, Ludovic Mouttet, Shihao Cui, Yasaman Hekmatnia, Mehran Mottahedi, Ida Derish, Naimeh Rafatian, Mark Aurousseau, Gregor Andelfinger, Renzo Cecere, Houman Savoji   +10 more
wiley   +1 more source

Correlation between β-catenin mutations and expression of Wnt-signaling target genes in hepatocellular carcinoma

Molecular Cancer, 2008
Aberrant Wnt-signaling caused by mutants of β-catenin, a key regulator of the canonical Wnt-signaling pathway, is frequently detected in cancer. Only recently, it was suggested that in hepatocellular carcinoma (HCC) the expression of the target gene ...
Gebhardt Rolf, Tannapfel Andrea, Wittekind Christian, Dunsch Ruediger, Austinat Madeleine, Gaunitz Frank   +5 more
doaj   +1 more source

Additional file 3: of Aberrantly expressed miR-188-5p promotes gastric cancer metastasis by activating Wnt/β-catenin signaling

, 2019
Table S2. Clinicopathological characteristics of studied patients and expression of miR-188-5p in STAD from the FMU Cohort. (DOCX 15 kb)
Li, Yun, Yan, Xiaoli, Shi, Jiajian, He, Yun, Xu, Jie, Lin, Liying, Chen, Wannan, Lin, Xinjian, Lin, Xu   +8 more
openaire   +1 more source

DataSheet1_Global role of IGF2BP1 in controlling the expression of Wnt/β-catenin-regulated genes in colorectal cancer cells.docx

, 2023
Introduction: Wnt/β-catenin signaling controls cell division and lineage specification during embryonic development, and is crucial for stem cells maintenance and gut tissue regeneration in adults.
Irina Elcheva (3844003), Vonn Walter (165501), Vladimir S. Spiegelman (10308404), Yuka Imamura Kawasawa (7254923), Vikash Singh (387413)   +4 more
core   +1 more source

Self‐Healing Hydrogel‐Enabled Modular Assembly of Bilayered Skin Construct for Hair Follicle Regeneration

Advanced Healthcare Materials, EarlyView.
Self‐healing assembly of two cell‐laden hydrogel layers creates a biomimetic skin construct that restores both dermal and epidermal functions, resulting in accelerated wound healing and enhanced hair follicle regeneration in a full‐thickness skin wound model. ABSTRACT Alopecia remains a pervasive clinical challenge, largely owing to the limited ability
JaeWook Park, Su Yong Kim, MinSu Jeong, Beom Joon Kim, Shin Hyuk Kang, Won‐Gun Koh   +5 more
wiley   +1 more source

Additional file 1: of The lncRNA NEAT1 activates Wnt/β-catenin signaling and promotes colorectal cancer progression via interacting with DDX5

, 2018
Supplemental materials and methods. (DOCX 20 kb)
Zhang, Meng, Weng, Weiwei, Zhang, Qiongyan, Wu, Yong, Ni, Shujuan, Tan, Cong, Xu, Midie, Sun, Hui, Liu, Chenchen, Wei, Ping, Du, Xiang   +10 more
openaire   +1 more source