Results 111 to 120 of about 262,733 (310)

Additional file 5: of RNA helicase p68 deploys β-catenin in regulating RelA/p65 gene expression: implications in colon cancer

, 2019
Table S1. List of primers used in the study. (DOCX 19 kb)
Veenita Khare, Shaheda Tabassum, Uttara Chatterjee, Sandip Chatterjee, Ghosh, Mrinal   +4 more
openaire   +1 more source

The RNA-binding protein hnRNPA2 regulates β-catenin protein expression and is overexpressed in prostate cancer [PDF]

, 2014
The RNA-binding protein hnRNPA2 (HNRNPA2B1) is upregulated in cancer, where it controls alternative pre-mRNA splicing of cancer-relevant genes. Cytoplasmic hnRNPA2 is reported in aggressive cancers, but is functionally uncharacterized.
Ahmad, Imran, Leung, Hing, Nixon, Colin, Rajan, Prabhakar, Stockley, Jacqueline, Villasevil, M. Eugenia M.   +5 more
core   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

Advanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

A transphyletic study of metazoan β-catenin protein complexes

Zoological Letters
Beta-catenin is essential for diverse biological processes, such as body axis determination and cell differentiation, during metazoan embryonic development.
Ivan Mbogo, Chihiro Kawano, Ryotaro Nakamura, Yuko Tsuchiya, Alejandro Villar-Briones, Yoshitoshi Hirao, Yuuri Yasuoka, Eisuke Hayakawa, Kentaro Tomii, Hiroshi Watanabe   +9 more
doaj   +1 more source

Oncogenic β-catenin mutations evade pH-regulated degradation

Molecular & Cellular Oncology, 2019
β-catenin has roles in cell-cell adhesion and Wnt signaling. We recently showed that β-catenin protein abundance is decreased at higher intracellular pH (pHi), mediated by pH-sensitive interaction with the beta-transducin repeat containing E3 ubiquitin ...
Bree K. Grillo-Hill, Katharine A. White
doaj   +1 more source

Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling.

PLoS ONE, 2017
Abnormal activation of the Wnt/β-catenin signaling is implicated in the osteoarthritis (OA) pathology. We searched for a pre-approved drug that suppresses abnormally activated Wnt/β-catenin signaling and has a potency to reduce joint pathology in OA.
Kentaro Miyamoto, Bisei Ohkawara, Mikako Ito, Akio Masuda, Akihiro Hirakawa, Tadahiro Sakai, Hideki Hiraiwa, Takashi Hamada, Naoki Ishiguro, Kinji Ohno   +9 more
doaj   +1 more source

S.6.1 β-catenin is a central mediator in SSc [PDF]

, 2017
Background. β-catenin is the central integrator of canonical Wnt signalling. Since recent evidence suggests a central role of Wnts in fibrosis, we examined the β-catenin/Wnt pathway in SSc and focused on the role of β-catenin in fibroblast activation ...
Abraham, D., Akhmetshina, A., Bergmann, C., Beyer, C., Beyer, C., Busnadiego, O., Carreira, P., Carter, D., de Crombrugghe, B., Dees, C., Dees, C., Dees, C., Distler, A., Distler, A., Distler, J. H. W., Distler, J. H. W., Distler, J. H. W., Distler, O., Distler, O., Distler, O., Fontaine, B., Garcia-Fernandez, R., Horn, A., Horn, A., Kapoor, M., Lagares, D., Lamas, S., Leask, A., Liu, S., MacDougald, O. A., Palumbo, K., Palumbo, K., Rodriguez-Pascual, F., Schett, G., Schett, G., Schett, G., Schramm, A., Shea, B., Shi-Wen, X., Tager, A., Taketo, M. M., Tomcik, M., Venalis, P., Zerr, P., Zerr, P.   +44 more
core  

β-catenin/cyclin D1 mediated development of suture mesenchyme in calvarial morphogenesis [PDF]

, 2010
Background Mouse genetic study has demonstrated that Axin2 is essential for calvarial development and disease. Haploid deficiency of β-catenin alleviates the calvarial phenotype caused by Axin2 deficiency. This loss-of-function study provides
Anthony J Mirando, Takamitsu Maruyama, Jiang Fu, Hsiao-Man Yu, Wei Hsu, Mirando, Anthony J   +5 more
core   +1 more source

ERK‐Mediated Phosphorylation of YAP Defines a Noncanonical FGF Signaling Mechanism in Stem Cells

Advanced Science, EarlyView.
With a powerful combination of in vivo, ex vivo, and in vitro models, the authors highlight a novel FGF‐ERK signaling regulation of YAP at the S128 site in neural crest‐derived stem cells. This study opens exciting new directions in stem cell biology and craniofacial biology, paving the way for potential innovations in the treatment of craniofacial ...
Xiaolei Zhao, Shannon Erhardt, Li Tang, Xiaotong Chen, Stephen M Farmer, Zixiu Cheng, Wen Chen, Ella Ziyuan Lu, Kihan Sung, Chang‐Ru Tsai, Mingjie Zheng, Sheng Zhang, Yang Liu, Jianxin Wang, Min Li, James F Martin, Jun Wang   +16 more
wiley   +1 more source

Additional file 2: of The lncRNA NEAT1 activates Wnt/β-catenin signaling and promotes colorectal cancer progression via interacting with DDX5

, 2018
Table S1. Primary antibodies for western blot. Table S2. Primers for real-time PCR. Table S3. Association between clinicopathological features and NEAT1 expression. Table S4. Univariate Cox proportional hazards model for overall survival (OS) and disease-free survival (DFS). Table S5. Multivariate Cox proportional hazards model for OS and DFS.
Zhang, Meng, Weng, Weiwei, Zhang, Qiongyan, Wu, Yong, Ni, Shujuan, Tan, Cong, Xu, Midie, Sun, Hui, Liu, Chenchen, Wei, Ping, Du, Xiang   +10 more
openaire   +1 more source