Results 151 to 160 of about 886,342 (318)

Characterisation of Aardvark, a Dictyostelium ß-catenin. [PDF]

, 2003
Wnt signalling is active both in development and the progression of certain disease processes, most notably cancer. Glycogen Synthase Kinase-3 (GSK-3) and ß-catenin both define the canonical Wnt pathway, where GSK-3 negatively regulates ß-catenin ...
Reynolds, Jonathan Peter, Reynolds, JP
core  

An anterior program of gene expression is up-regulated after β-catenin-1 inhibition in acoels.

, 2019
(A) Experimental scheme for RNA sequencing. Hofstenia miamia were injected once a day for three consecutive days with control or β-catenin-1 dsRNA. Tails were collected in trizol at 3, 7, and 14 days after the first injection for RNA sequencing.
Daniel E. Wagner (7517981), Jared H. Owen (7517975), Aneesha G. Tewari (7517972), Christian P. Petersen (7517978), Peter W. Reddien (7517984)   +4 more
core   +1 more source

Additional file 4 of TRIP6 enhances stemness property of breast cancer cells through activation of Wnt/β-catenin

, 2020
Additional file 4: Fig. S3. The mRNA levels of the downstream targets of Wnt/β-catenin signaling, including c-MYC, TCF1, CD133 and CD44 in indicated breast cancer ...
Qingnan Liu (2416333), Chao Jiang (122046), Yan Zhang (8098), Rui Xu (158313), Xiaohui Zhao (137556), Guanglin Liu (350758)   +5 more
core   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Additional file 1: Table S1. of Effects of hepatitis C virus core protein and nonstructural protein 4B on the Wnt/β-catenin pathway

, 2017
Primers for PCR. (DOCX 17Â kb)
Jiang, Xiao-Hua, Xie, Yu-Tao, Cai, Ya-Ping, Ren, Jing, Ma, Tao   +4 more
openaire   +1 more source

Identification and characterisation of a novel integral membrane protein, shrew-1 that complexes with adherens junctions in polarised cells

, 2005
In an attempt to search for potential candidate molecules involved in the pathogenesis of endometriosis, a novel 2910 bp cDNA encoding a putative 411 amino acid protein, shrew-1 was discovered. By computational analysis it was predicted to be an integral
Bharti, Sanita
core  

Aptamer‐Directed Porous DNA Nanocomposite Hydrogel for Active Pulp Preservation: Immunomodulation, Stem Cell Recruitment and Reparative Dentinogenesis

Advanced Science, EarlyView.
This study presents an injectable DNA‐based porous hydrogel integrating catechol motifs and targeting aptamers for pulpitis management. Upon in situ crosslinking, the scaffold actively recruits endogenous dental pulp stem cells, restores redox homeostasis, and modulates immune responses.
Luhui Cai, Huan Yu, Zihan Ni, Kan Chen, I‐Chen Tsai, Zeyu Bao, Shuo Sun, Weichang Li, Yunhua Chen, Qiong Xu   +9 more
wiley   +1 more source

Activation of β-catenin signalling leads to temporomandibular joint defects [PDF]

European Cells & Materials, 2014
Despite extensive research in knee and hip osteoarthritis (OA), the underlying mechanism of temporomandibular joint (TMJ) disorder remains largely unknown. The purpose of this study was to determine whether the constitutive activation of β-catenin in the
M Wang, S Li, W Xie, J Shen, H-J Im, JD Holz, M Wang, TGH Diekwisch, D Chen   +8 more
doaj  

Additional file 2: of Nucleolar and spindle associated protein 1 promotes metastasis of cervical carcinoma cells by activating Wnt/β-catenin signaling

, 2019
Table S2. Cox regression univariate andmultivariate analyses of prognostic factors in cervical cancer patients. (DOCX 15 kb)
Li, Han, Zhang, Weijing, Yan, Ming, Qiu, Jiaqi, Chen, Jueming, Sun, Xiaoying, Chen, Xiangfu, Song, Libing, Zhang, Yanna   +8 more
openaire   +1 more source

UVB represses melanocyte cell migration and acts through β-catenin

, 2017
The exposure of skin to ultraviolet (UV) radiation can have both beneficial and deleterious effects: it can lead, for instance, to increased pigmentation and vitamin D synthesis but also to inflammation and skin cancer.
Larue, Lionel, Bertrand, Juliette U., Sage, Evelyne, Lionel Larue, Bertrand, Juilette U., Irina Berlin, Petit, Valérie, David C. Whiteman, Valérie Petit, Marie Pouteaux, Hacker, Elke, Berlin, Irina, Juliette U. Bertrand, Elke Hacker, Evelyne Sage, Hayward, Nicholas K., Whiteman, David C., Nicholas K. Hayward, Pouteaux, Marie   +18 more
core   +1 more source