Results 171 to 180 of about 1,680,534 (386)

Loss of β-catenin in cholangiocytes promotes hepatocyte reprogramming and vascular remodeling during murine cholestasis

Cell Communication and Signaling
Background & aims The Wnt/β-catenin signaling pathway is critical for liver homeostasis. We have previously shown that hepatocyte β-catenin plays a pleiotropic role in cholestatic injury.
Matthew Carson, Jamie Fornsaglio, Ridgeway Case IV, Rithwik Aggarwal, Vik Meadows, Chang Kyung Kim, Laura Molina, Pamela Cornuet, Jia-Jun Liu, Silvia Liu, Kari Nejak-Bowen   +10 more
doaj   +1 more source

MOESM1 of A tannin compound from Sanguisorba officinalis blocks Wnt/β-catenin signaling pathway and induces apoptosis of colorectal cancer cells

, 2019
Additional file 1. Minimum standards of reporting checklist.
Li, Wa, Yang, Chun-juan, Wang, Li-qian, Wu, Juan, Dai, Cong, Yuan, Yue-mei, Li, George, Yao, Mei-cun   +7 more
openaire   +1 more source

YAP promotes osteogenesis and suppresses adipogenic differentiation by regulating β-catenin signaling

Bone Research, 2018
YAP (yes-associated protein) is a transcriptional factor that is negatively regulated by Hippo pathway, a conserved pathway for the development and size control of multiple organs. The exact function of YAP in bone homeostasis remains controversial. Here
Jin-Xiu Pan, Lei Xiong, Kai Zhao, Peng Zeng, Bo Wang, Fu-lei Tang, Dong Sun, Hao-han Guo, Xiao Yang, Shun Cui, Wen-Fang Xia, L. Mei, W. Xiong   +12 more
semanticscholar   +1 more source

Bone Healing Around Implants in Normal and Medically Compromised Conditions: Osteoporosis and Diabetes

Advanced Healthcare Materials, EarlyView.
xx xx. ABSTRACT Osseointegration of orthopedic and dental implants is influenced by local and systemic factors, including their physicochemical surface properties and the patient's overall health status. Titanium and its alloys have been a longstanding standard for bone implants due to their innate biocompatibility and mechanical properties.
Dainelys Guadarrama Bello, Fabio Variola, Antonio Nanci   +2 more
wiley   +1 more source

Beta-catenin Forms Protein Aggregation at High Concentrations in HEK293TCells

Iranian Journal of Medical Sciences, 2017
Background: The canonical Wnt signal transduction (or the Wnt/β-catenin pathway) plays a crucial role in the development of animals and in carcinogenesis. Beta-catenin is the central component of this signaling pathway.
Marie Saghaeian Jazi, Seyed Mahmoud Arab Najafi   +1 more
doaj  

Redistribution of β-catenin in response to EGF and lithium signalling in human oesophageal squamous carcinoma cell lines

Cancer Cell International, 2003
Background The β-catenin link between membrane-bound cadherins and the actin cytoskeleton regulates cell adhesion and consequently metastasis. Abnormal stabilisation of β-catenin enhances its transcriptional activities.
Veale Rob B, Jones Lindsay JG
doaj   +1 more source

Additional file 1: of The lncRNA NEAT1 activates Wnt/β-catenin signaling and promotes colorectal cancer progression via interacting with DDX5

, 2018
Supplemental materials and methods. (DOCX 20 kb)
Zhang, Meng, Weng, Weiwei, Zhang, Qiongyan, Wu, Yong, Ni, Shujuan, Tan, Cong, Xu, Midie, Sun, Hui, Liu, Chenchen, Wei, Ping, Du, Xiang   +10 more
openaire   +1 more source

HIF1α protects from osteoarthritis by inhibiting MMP13 expression through WNT/ β-catenin signaling [PDF]

, 2016
W. Bouaziz, Johanna Sigaux, Claire-Sophie Devignes, Thomas Funck‐Brentano, K. Ea, Dominique Modrowski, Sylvain Provot, Martine Cohen‐Solal, Eric Haÿ   +8 more
openalex   +1 more source

Long Noncoding RNA NEAT1, Regulated by the EGFR Pathway, Contributes to Glioblastoma Progression Through the WNT/β-Catenin Pathway by Scaffolding EZH2

Clinical Cancer Research, 2017
Purpose: Long noncoding RNAs have been implicated in gliomagenesis, but their mechanisms of action are mainly undocumented. Through public glioma mRNA expression data sets, we found that NEAT1 was a potential oncogene.
Qun Chen, Jinquan Cai, Qixue Wang, Yunfei Wang, Mingyang Liu, Jingxuan Yang, Junhu Zhou, C. Kang, Min Li, Chuanlu Jiang   +9 more
semanticscholar   +1 more source

siRNA Delivery via Cross‐Linked Gelatin Microparticles Enables Targeted Modulation of Osteogenic‐Vascular Cross‐Talk: An Advanced Human 3D in Vitro Test System for Therapeutic siRNA

Advanced Healthcare Materials, EarlyView.
Osteogenic‐angiogenic cross‐talk is a vital prerequisite for vascularized bone regeneration. In this study, we investigated the effects of siRNA‐mediated silencing of two inhibitory proteins, Chordin and WWP‐1, via CaP‐NP‐loaded gelatin microparticles in osteogenically differentiated microtissues.
Franziska Mitrach, Jonas Kubat, Stefan Simm, Alexandra H. Springwald, Burak Demir, Anton Liebezeit, Michael C. Hacker, Michaela Schulz‐Siegmund   +7 more
wiley   +1 more source