Results 51 to 60 of about 1,062,506 (300)

Aberrant nuclear localization of β-catenin without genetic alterations in β-catenin or Axin genes in esophageal cancer

World Journal of Surgical Oncology, 2007
Background β-catenin is a multifunctional protein involved in two apparently independent processes: cell-cell adhesion and signal transduction. β-catenin is involved in Wnt signaling pathway that regulates cellular differentiation and proliferation.
Shinoda Noriyuki, Sugiura Hironori, Terashita Yukio, Shibata Yasuyuki, Ishiguro Hideyuki, Haruki Nobuhiro, Nishiwaki Tadashi, Kudo Junzo, Kimura Masahiro, Kuwabara Yoshiyuki, Fujii Yoshitaka   +10 more
doaj   +1 more source

Ectopic γ-catenin expression partially mimics the effects of stabilized β-catenin on embryonic stem cell differentiation. [PDF]

PLoS ONE, 2013
β-catenin, an adherens junction component and key Wnt pathway effector, regulates numerous developmental processes and supports embryonic stem cell (ESC) pluripotency in specific contexts.
Sujeivan Mahendram, Kevin F Kelly, Sabrina Paez-Parent, Sharmeen Mahmood, Enio Polena, Austin J Cooney, Bradley W Doble   +6 more
doaj   +1 more source

Additional file 8: of Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma

, 2019
Table S1. Clinicopathological characteristics of 102 HCC patients. (DOC 38 kb)
Deng, Ling, Sun, Jingyuan, Chen, Xiaohui, Liu, Li, Wu, Dehua   +4 more
openaire   +1 more source

Additional file 1: of Wnt/β-catenin-mediated signaling re-activates proliferation of matured cardiomyocytes

, 2018
Figure S1. Upregulation of Wnt signaling leads to proliferation of human ES cell-derived cardiomyocytes. Figure S2. Expression levels of Wnt signaling genes are affected in a cardiac hypertrophy model. Table S1. Lists of human and murine primer sequences used in this study. (DOCX 167 kb)
Fan, Yong, Ho, Beatrice, Pang, Jeremy, Pek, Nicole, Hor, Jin, Ng, Shi-Yan, Soh, Boon-Seng   +6 more
openaire   +1 more source

Additional file 10: of Nek2 augments sorafenib resistance by regulating the ubiquitination and localization of β-catenin in hepatocellular carcinoma

, 2019
Table S3. Univariate and multivariate analyses of OS in 102 HCC patients by Cox regression analysis. (DOCX 14 kb)
Deng, Ling, Sun, Jingyuan, Chen, Xiaohui, Liu, Li, Wu, Dehua   +4 more
openaire   +1 more source

An examination of VEGF, its receptors and the adherens junction component, β-catenin in the development of primary varicose veins [PDF]

, 2010
Vascular endothelial growth factor (VEGF-A) plays a central role in the maintenance of vascular reactivity and its aberrant control/function is implicated in the development of varicose veins (VVs).
Powell, G.L.
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

MOESM1 of Wnt/β-catenin signaling contributes to articular cartilage homeostasis through lubricin induction in the superficial zone

, 2019
Additional file 1: Table S1. Primers used for RT-qPCR.
Xuan, Fengjun, Yano, Fumiko, Mori, Daisuke, Chijimatsu, Ryota, Maenohara, Yuji, Nakamoto, Hideki, Mori, Yoshifumi, Makii, Yuma, Oichi, Takeshi, Taketo, Makoto, Hojo, Hironori, Ohba, Shinsuke, Chung, Ung-il, Tanaka, Sakae, Saito, Taku   +14 more
openaire   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Nanog safeguards early embryogenesis against global activation of maternal β-catenin activity by interfering with TCF factors.

PLoS Biology, 2020
Maternal β-catenin activity is essential and critical for dorsal induction and its dorsal activation has been thoroughly studied. However, how the maternal β-catenin activity is suppressed in the nondorsal cells remains poorly understood.
Mudan He, Ru Zhang, Shengbo Jiao, Fenghua Zhang, Ding Ye, Houpeng Wang, Yonghua Sun   +6 more
doaj   +1 more source