Results 121 to 130 of about 2,747,637 (331)
Advanced Science, EarlyView.Diabetic bone defects remain a critical clinical challenge. A 3D‐printed BCPG‐MF@Y scaffold, embedding Yoda1‐functionalized manganese dioxide‐ferritin nanozymes, scavenges mtROS, suppresses the cGAS–STING pathway, and reverses cellular senescence, while Yoda1 activates Piezo1 to direct BMSCs fate to synergistically reprogram the osteoimmune ...
Qing‐Song Deng +16 more
wiley +1 more source
Hepatology, EarlyView., 2022 Abstract Background and Aims Intrahepatic cholangiocarcinoma (ICC) is a deadly but poorly understood disease, and its treatment options are very limited. The aim of this study was to identify the molecular drivers of ICC and search for therapeutic targets.
Yuto Shiode +16 more
wiley +1 more source
2.2 Å resolution cryo-EM structure of β-galactosidase in complex with a cell-permeant inhibitor
Science, 2015 Pushing the limits of electron microscopy Recent advances in cryo–electron microscopy (cryo-EM) allow structures of large macromolecules to be determined at near-atomic resolution.
A. Bartesaghi +6 more
semanticscholar +1 more source
Beta (β)-galactosidase is a lysosomal enzyme that removes terminal galactose residues from glycolipids and glycoproteins. It is upregulated in, and used as a marker for, senescent cells.
Guy C. Brown (7848366) +2 more
core +1 more source
Identification of a Hypothetical Protein of Plant Pathogenic Xanthomonas campestris as a Novel β-galactosidase [PDF]
, 2010 [[abstract]]Xc17L, a lactose-utilizing mutant of Xanthomonas campestris pv. campestris previously isolated by mutagenesis with nitrous acid, displays a level of β-galactosidase 3.5-fold higher than that in the parental Xc17.
Yang TC; Hu RM ; Weng SF ; Tseng YH
core
Advanced Science, EarlyView.Genome‐wide CRISPRi and RNA‐seq resolve how B. thetaiotaomicron converts host mucosal glycans into fitness. The study reveals a layered mucin‐utilization architecture in which capsular polysaccharides constrain surface access, extracellular CAZymes and peptidases show functional redundancy, and intracellular catabolic pathways create discrete metabolic
Kangsan Kim +5 more
wiley +1 more source
Hepatology, EarlyView., 2022 IL‐31 levels correlate with pruritus in patients with cholestatic and metabolic liver diseases Abstract Background and Aims Pruritus is associated with multiple liver diseases, particularly those with cholestasis, but the mechanism remains incompletely understood.
Jun Xu +20 more
wiley +1 more source
Study of β-Galactosidase Enzyme Activity Produced by Lactobacilli in Milk and Cheese
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2012 <p>Background and objective Lactose intolerance is a discomfort state that occurs in some people after ingestion of milk and it is due to insufficient amount of beta galactosidase in the human gut to digest lactose.
J Nowroozi
doaj
In vivo fate of bone marrow mesenchymal stem cells implanted into rat pulpotomized molars
Stem Cell Research, 2019 In our previous work, we established an in vivo coronal pulp regeneration model in which biodegradable hydrogel-made scaffolds carrying rat bone marrow mesenchymal stem cells (BM-MSCs) were implanted in the coronal pulp chamber of pulpotomized rat ...
Tomoatsu Kaneko +8 more
doaj +1 more source
A novel near-infrared fluorescent probe for sensitive detection of β-galactosidase in living cells
Analytica Chimica Acta, 2017 A novel near-infrared fluorescent probe for β-galactosidase has been developed based on a hemicyanine skeleton, which is conjugated with a D-galactose residue via a glycosidic bond.
Jingtuo Zhang +8 more
semanticscholar +1 more source