Results 171 to 180 of about 2,910 (220)

Interactions of Mucus Monosaccharides and the Epidermal Microbiome in Four Benthic Elasmobranchs

Environmental Microbiology Reports, Volume 18, Issue 2, April 2026.
Here we collected mucus and microbes from the skin of Elasmobranchs to identify interactions between mucus and the microbial community. We identified key microbial genes involved in the metabolism of mucus carbohydrates in Elasmobranchs. ABSTRACT Epidermal mucus is a complicated mixture of macromolecules which acts as the first line of defence for ...
Emma N. Kerr, Long Yu, Ryan D. Hesse, Chloe N. Roberts, Vincent Bulone, Lauren Meyer, Robert A. Edwards, Michael P. Doane, Elizabeth A. Dinsdale   +8 more
wiley   +1 more source

Tacrolimus Induced Hypertension and Vascular Remodeling Includes Mechanisms of Cellular Senescence—The Protective Effect of Valsartan

Acta Physiologica, Volume 242, Issue 4, April 2026.
ABSTRACT Aim Calcineurin inhibitors (CNI) such as tacrolimus (Tac) are the first‐line treatment to prevent transplant rejection. However, CNI have adverse effects on blood vessels and renal function, which may be linked to cellular senescence. Valsartan, a common angiotensin II type 1 receptor (AT1R) blocker, exhibits anti‐senescence properties.
Lingyan Fei, Xiaohua Wang, Lingyi Kong, Tianjiao Cui, Pratik H. Khedkar, Yunxiu Xiang, Dongliang Zhao, Junxuan Fang, Yulin Liang, Yangyang Zhang, Nan Xu, Xingyu Qiu, Liang Zhao, Gensheng Zhang, Yan Lei, Chun Tang, Kongyang Ma, Liwei Lu, Jin Wei, En Yin Lai, Pontus B. Persson, Andreas Patzak, Zhihua Zheng, Shan Jiang   +23 more
wiley   +1 more source

A New <i>β</i>-Galactosidase from <i>Pseudomonas tritici</i> SWRI145 for Efficient Bioproduction of Galactooligosaccharides. [PDF]

Foods
Jin X, Cheng Z, Zhang Y, Petrova P, Petrov K, Zhang W, Mu W.   +6 more
europepmc   +1 more source

First Detection of Lactococcus formosensis subsp. formosensis in Rainbow Trout (Oncorhynchus mykiss) in Europe

Journal of Fish Diseases, Volume 49, Issue 4, April 2026.
ABSTRACT Lactococcus garvieae, Lactococcus petauri and Lactococcus formosensis are etiological agents of piscine lactococcosis, a disease reported in Italy since the early 1990s and linked to significant aquaculture losses. To the best of our knowledge, this study reports the first detection of L. formosensis subsp. formosensis in farmed rainbow trout (
Silvia Colussi, Giuseppe Esposito, Khalid Shahin, Pier Luigi Acutis, Lucio Fariano, Claudio Ghittino, Maria Goria, Fabio Bondavalli, Paolo Ajmone Marsan, Giorgia Bignami, Elena Bozzetta, Marino Prearo, Paolo Pastorino   +12 more
wiley   +1 more source

Rhizobial motility preference in root colonization of Medicago truncatula

New Phytologist, Volume 250, Issue 1, Page 547-562, April 2026.
Summary Tunnel‐like infection thread (IT) structures support root colonization by symbiotic nitrogen‐fixing rhizobia bacteria in most legume species. These tip‐grown structures are key to directing rhizobia from root hairs to developing nodules, where they are hosted to fix nitrogen.
Anaïs Delers, Anne Bennion, Ambre Guillory, Lisa Frances, Elizaveta Krol, Fanny Bonnafous, Laurena Medioni, Javier Serrania, Rémi Peyraud, Joëlle Fournier, Fernanda de Carvalho‐Niebel, Anke Becker   +11 more
wiley   +1 more source

Adhesive Photoinitiator Constructs Polymer Jackets on Enzymes: Direct, Release‐Free Cytosolic Delivery

Angewandte Chemie, Volume 138, Issue 11, 9 March 2026.
A supramolecular adhesive photoinitiator, GuCD⊃BP‐SH, overcomes a central dilemma in enzyme therapeutics. The initiator, featuring a guanidinium‐modified cyclodextrin (GuCD) host, triggers formation of a semi‐permeable polymer jacket directly on an enzyme.
Shuran He, Soumen Ghosh, Kou Okuro
wiley   +2 more sources

Expression, Purification, and Functional Exploration of an α-Galactosidase from <i>Akkermansia muciniphila</i>. [PDF]

Foods
Zuo T, Yin Z, Li Z, Ren Z, Chen Y, Yu D, Fang X.   +6 more
europepmc   +1 more source

ZNF384‐Driven Fibulin‐1 Exacerbates Vascular Stiffness via TGF‐β/Smad3‐Mediated Senescence and Fibrosis

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
This article elucidates the regulatory molecular mechanisms of Fibulin‐1 (Fbln1) in vascular stiffness and explores potential therapeutic interventions. Zinc Finger Protein 384 (ZNF384) binds to the Fbln1 promoter, driving its expression. Fbln1 activates the TGF‐β/Smad3 axis, promoting vascular smooth muscle cell (VSMC) senescence and collagen ...
Dan Yan, Tianyi ji, Xiaolu Liang, Mandi Luo, Yi Huang, Pengcheng Luo, Zhen Yang, Le Zhang, Tao Li, Yong Ping Bai, Cuntai Zhang, Lei Ruan   +11 more
wiley   +1 more source

Safety of the extension of use of galacto-oligosaccharides as a novel food pursuant to Regulation (EU) 2015/2283. [PDF]

EFSA J
EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Turck D, Bohn T, Cámara M, Castenmiller J, De Henauw S, Jos Á, Maciuk A, Mangelsdorf I, McNulty B, Naska A, Pentieva K, Siani A, Thies F, Aguilera-Gómez M, Frenzel T, McArdle HJ, Moldeus P, Neuhäuser-Berthold M, Schlatter JR, van Loveren H, Turla E, Azzollini D, Hirsch-Ernst KI.   +24 more
europepmc   +1 more source

UGA4 and YBR062C Regulate Oxidative Stress Tolerance Under Heavy Metal Toxicity

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
Under heavy metal stress, global cap‐dependent translation is compromised. However, expression of URE2, a key gene involved in cellular tolerance to heavy metal toxicity, is maintained through an internal ribosome entry site (IRES)–mediated mode of translation.
Mustafa Al‐gafari, Houman Moteshareie, Thomas D. D. Kazmirchuk, Jiashu Wang, Sarah Takallou, Parvin Khosravifar, Mohsen Hooshyar, Bahram Samanfar, Ashkan Golshani   +8 more
wiley   +1 more source