Results 101 to 110 of about 937,622 (274)

Profiles of phenotype resistance to antibiotic other than β-lactams in Klebsiella pneumoniae ESBLs-producers, carrying blaSHV genes.

Folia Histochemica et Cytobiologica, 2011
Extended spectrum β-lactamases production is one of the most common mechanism of resistance to extended spectrum β-lactam antibiotics is increasing worldwide. Twenty five strains of Klebsiella pneumoniae isolated from clinical specimens were tested. Based on the phenotypic confirmatory test all these strains were defined as ESBL producers named ESBL(+).
Małgorzata Krawczyk, Robert Milewski, Tomasz Hauschild, Andrzej Szpak, Piotr Wieczorek, Dominika Ojdana, Paweł Sacha, Katarzyna Kaczyńska, Elżbieta Tryniszewska   +8 more
openaire   +5 more sources

Rewriting Tumor Immunity With Bacterial Membrane Vesicles: A Versatile and Potent Therapeutic Strategy

Advanced NanoBiomed Research, EarlyView.
Bacterial membrane vesicles (BMVs) emerge as promising platforms for cancer immunotherapy owing to their intrinsic adjuvant properties and tunable cargo delivery capabilities. Their ability to modulate the tumor microenvironment, enhance antitumor immune responses, and support personalized therapeutic strategies highlights their growing potential as ...
Md Sifat Rahi, Md Mijanur Rahman, Asma Talukder, Urooj Yousaf Virk, Jennifer C. Wilson, Nigel McMillan, Ming Q. Wei   +6 more
wiley   +1 more source

Novel β-lactam-β-lactamase inhibitor combinations: expectations for the treatment of carbapenem-resistant Gram-negative pathogens

, 2019
Introduction: The burden of antimicrobial resistance among Gram-negative bacteria is increasing and growing into a major threat of public health. Treatment options for carbapenem-resistant Enterobacteriaceae are limited and resistance rates to existing ...
Irene Galani (6193556), Helen Giamarellou (65000), Ilias Karaiskos (4370434), Maria Souli (3828589)   +3 more
core   +1 more source

Ruthenium‐Catalyzed Nitrile‐Acrylate Reductive Coupling by 2‐Propanol: Synthesis of Enantioenriched β‐Amino Esters

Angewandte Chemie, EarlyView.
The first nitrile reductive couplings beyond stoichiometric metals or metalloids are described. Using a ruthenium catalyst derived from RuHCl(CO)(PPh3)3 and Cy‐BIPHEP, 2‐propanol‐mediated reductive coupling of phenyl acrylate with aromatic or aliphatic nitriles delivers α,β‐unsaturated β‐amino esters.
Sebastian Höthker, Colin E. Hayter, Weijia Shen, Michael J. Krische   +3 more
wiley   +2 more sources

The Effect of Aqueous Extract and Essential Oils of the Leaves of Eucalyptus incrassate on β- Lactam Resistant Staphylococcus aureus

Ibn Al-Haitham Journal for Pure and Applied Sciences, 2017
According to the extraction procedure , Eucalyptus incrassata leave sample yielded 5% and 2% w/w(Based on dry leaves ) of the aqueous extract and essential oils respectively. Disk diffusion method was used to determine the antimicrobial activity of aqueous extract and essential oils of E .
Ehab D. Salman, Abbas J. H. AL-Saedi, Amel Gh. M. AL-Kazzaz, Suhad S. Yahya   +3 more
openaire   +1 more source

Total Synthesis of the Novel, Immunosuppressive Agent (−)-Pateamine A from Mycale sp. Employing a β-Lactam-Based Macrocyclization

, 2016
Total Synthesis of the Novel, Immunosuppressive Agent (−)-Pateamine A from Mycale sp.
Daniel Romo (246583), Robert M. Rzasa (1692925), Helene A. Shea (2705461)   +2 more
core   +1 more source

Conjugation of Polycationic Peptides Extends the Efficacy Spectrum of β‐Lactam Antibiotics

Advanced Science
Antibiotic‐resistant enterococci represent a significant global health challenge. Unfortunately, most β‐lactam antibiotics are not applicable for enterococcal infections due to intrinsic resistance.
Julia Werner, Florian Umstätter, Manuel B. Böhmann, Hannah Müller, Barbro Beijer, Tobias Hertlein, Laura Kaschnitz, Veronika Bram, Christian Kleist, Karel D. Klika, Eric Mühlberg, Gabriel Braune, Sabrina Wohlfart, Martin Gärtner, Silke Peter, Stefan Zimmermann, Uwe Haberkorn, Knut Ohlsen, Heike Brötz‐Oesterhelt, Walter Mier, Philipp Uhl   +20 more
doaj   +1 more source

β‐Lactam allergy testing and delabeling—Experiences and lessons from Singapore

Immunity, Inflammation and Disease, 2020
Background β‐Lactam allergy is over‐reported and this leads to greater healthcare costs. Allergy testing has inherent risks, yet patients who test negative may continue avoiding β‐lactams.
Yee Kiat Heng, Yasmin Chia Chia Liew, Yan Ling Kong, Yen Loo Lim   +3 more
doaj   +1 more source

Chemoselective Synthesis of β-Amino Ester or β-Lactam via Sonochemical Reformatsky Reaction

, 2014
A series of β-amino esters were synthesized by the reaction of N-tosyl aldimine or N-hydroxy aldimine with bromoacetate by sonochemical Reformatsky reaction. The β-N-hydroxyamino ester was obtained and the formed sensitive hydroxylamino functionality was
Lee, Adam Shih-Yuan; Chang, Yu-Ting; Su, Feng-Yi
core   +1 more source

In vitro activity of cefiderocol against European Enterobacterales, including isolates resistant to meropenem and recentβ-lactam/β-lactamase inhibitor combinations

Microbiology Spectrum
Carbapenem-resistant Enterobacterales represent a major health threat and have few approved therapeutic options. Enterobacterales isolates were collected from hospitalized inpatients from 49 sites in six European countries (1 January–31 December 2020 ...
Anne Santerre Henriksen, Fabio Arena, Marie Attwood, Rafael Canton, Sören Gatermann, Thierry Naas, Ian Morrissey, Christopher Longshaw   +7 more
doaj   +1 more source