Results 41 to 50 of about 144,498 (294)
Stability of β-lactam antibiotics in bacterial growth media
bioRxiv, 2020 Laboratory assays such as MIC tests assume that antibiotic molecules are stable in the chosen growth medium - but rapid degradation has been observed for antibiotics including β-lactams under some conditions in aqueous solution.
Rebecca Brouwers +5 more
semanticscholar +1 more source
Rapid optical determination of β-lactamase and antibiotic activity [PDF]
, 2014 Background: The absence of rapid tests evaluating antibiotic susceptibility results in the empirical prescription of antibiotics. This can lead to treatment failures due to escalating antibiotic resistance, and also furthers the emergence of drug ...
Hasan, Tayyaba +4 more
core +1 more source
JAMA Network Open, 2020 Key Points Question Are mortality and recurrent bacteremia different for patients who receive oral β-lactam antibiotics vs fluoroquinolones or trimethoprim-sulfamethoxazole for definitive treatment of Enterobacterales bacteremia from a urinary source ...
J. Sutton +5 more
semanticscholar +1 more source
Antibiotic residues and antibiotic-resistant bacteria in pig slurry used to fertilize agricultural fields [PDF]
, 2020 Pig manure may contain antibiotic residues, antibiotic-resistant bacteria or pathogens, which may reach the environment upon fertilization. During this study, 69 antibiotic residues belonging to 12 classes were quantified in 89 pig slurry samples.
Colson, Lander +9 more
core +2 more sources
Dose-Response, 2014 Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of hospital- and community-associated infections. The formation of adherent clusters of cells known as biofilms is an important virulence factor in MRSA pathogenesis.
Mandy Ng +7 more
doaj +1 more source
Pharmacotherapy, 2019 Minimizing the duration of broad‐spectrum antimicrobial exposure in the critically ill is a commonly used strategy aimed at preventing resistance. Our objective was to correlate the duration of exposure to antipseudomonal β‐lactam antibiotics with the ...
Besu F. Teshome +4 more
semanticscholar +1 more source
The porin and the permeating antibiotic: A selective diffusion barrier in gram-negative bacteria [PDF]
, 2008 Gram-negative bacteria are responsible for a large proportion of antibiotic resistant bacterial diseases. These bacteria have a complex cell envelope that comprises an outer membrane and an inner membrane that delimit the periplasm.
A Baslé +95 more
core +1 more source
Comparison between a direct-flow SPR immunosensor for ampicillin and a competitive conventional amperometric device: analytical features and possible applications to real samples [PDF]
, 2017 In this research, we developed a direct-flow surface plasmon resonance (SPR) immunosensor for ampicillin to perform direct, simple, and fast measurements of this important antibiotic.
Campanella, Luigi +6 more
core +2 more sources
Could β-Lactam Antibiotics Block Humoral Immunity?
Frontiers in Immunology, 2021 It has been reported that treatment with β-lactam antibiotics induces leukopenia and candidemia, worsens the clinical response to anticancer immunotherapy and decreases immune response to vaccination.
Cléa Melenotte +13 more
doaj +1 more source
International Journal of Molecular Sciences, 2020 Gram-negative bacteria have an outer membrane inhibiting the entry of antibiotics. Porins, found within the outer membrane, are involved in regulating the permeability of β-lactam antibiotics.
Si Won Kim +15 more
semanticscholar +1 more source