Results 31 to 40 of about 61,534 (259)

Resistance to β-lactam antibiotics conferred by point mutations in penicillin-binding proteins PBP3, PBP4 and PBP6 in Salmonella enterica. [PDF]

PLoS ONE, 2014
Penicillin-binding proteins (PBPs) are enzymes responsible for the polymerization of the glycan strand and the cross-linking between glycan chains as well as the target proteins for β-lactam antibiotics.
Song Sun, Maria Selmer, Dan I Andersson
doaj   +1 more source

β-lactam antibiotic versus combined β-lactam antibiotics and single daily dosing regimens of aminoglycosides for treating serious infections: A meta-analysis [PDF]

, 2019
Background: Combining aminoglycosides with β-lactam antibiotics for treating serious infections has not been associated with reduced mortality in previous meta-analyses.
Roberts, Prof Jason, Grimwood, Keith, Andrews, Katherine, Heffernan, Aaron James, Sime, Fekade Bruck, Sun, Jing, Ellwood, David, Kumar, Anand, Lipman, Prof Jeffrey   +8 more
core   +1 more source

FtsH Sensitizes Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics by Degrading YpfP, a Lipoteichoic Acid Synthesis Enzyme [PDF]

, 2021
In the Gram-positive pathogen Staphylococcus aureus, FtsH, a membrane-bound metalloprotease, plays a critical role in bacterial virulence and stress resistance.
Taeok Bae, Kim, Kyeong Kyu, Jeong, Bohyun, Yeo, Won-Sik, Nimat Ullah, Ullah, Nimat, Won-Sik Yeo, Majid Ali Shah, Amjad Ali, Bae, Taeok, Kyeong Kyu Kim, Majid Shah, Kyeong Kim, Shah, Majid Ali, Ali, Amjad, Bohyun Jeong   +15 more
core   +1 more source

Bacterial Resistance to β-Lactam Antibiotics in Municipal Wastewater: Insights from a Full-Scale Treatment Plant in Poland

Microorganisms, 2022
This study investigated enzymatic and genetic determinants of bacterial resistance to β-lactam antibiotics in the biocenosis involved in the process of biological treatment of wastewater by activated sludge.
Natalia Jendrzejewska, Ewa Karwowska
doaj   +1 more source

Ethane-β-Sultam Modifies the Activation of the Innate Immune System Induced by Intermittent Ethanol Administration in Female Adolescent Rats [PDF]

, 2014
Intermittent ethanol abuse or ‘binge drinking’ during adolescence induces neuronal damage, which may be associated with cognitive dysfunction. To investigate the neurochemical processes involved, rats were administered either 1 g/kg or 2 g/kg ethanol in ...
Colivicchi Ma, Stefanini C, Hemmings, K., Colivicchi, M.A., Stefanini, C., Della Corte, L., Dexter, D T, De Witte, P, Colivicchi, Stefanini C, Nayak, K., de Witte, Philippe, Pitard, A., Page, M.I., Corte, Della, Pittard, A., Lallemand, f, Ward, Roberta, Ward, Roberta J., Hemmings, Karl, Hemming, Karl, Lallemand, Frederic, Page, Michael I., Dexter, D. T., Dexter, David T., Page, Michael, Nayak, K, Corte, Laura Della   +25 more
core   +1 more source

β-lactam Antibiotics used for this study. [PDF]

, 2015
β-lactam Antibiotics used for this study.
Kristina Crona (567679), Bernd Sturmfels (73407), Portia M. Mira (735579), Miriam Barlow (197488), Juan C. Meza (735580), Devin Greene (567678)   +5 more
core   +1 more source

Outer membrane vesicles from β-lactam-resistant Escherichia coli enable the survival of β-lactam-susceptible E. coli in the presence of β-lactam antibiotics [PDF]

, 2018
Outer membrane vesicles (OMVs) containing various bacterial compounds are released from mainly gram-negative bacteria. Secreted OMVs play important roles in the ability of a bacterium to defend itself, and thus contribute to the survival of bacteria in a
Jong-Su Seo, Suk-Kyung Lim, Se Pyeong Im, Jaesung Kim, Jong-Hwan Kim, Tae Sung Jung, Jung Seok Lee, Jae Wook Jung, Gwang Joong Kim, Seong Bin Park, Jong-Wook Song, Young Ju Lee, Si Won Kim, Hyun Suk Jung, Tae Won Gong, Jassy Mary S. Lazarte   +15 more
core   +1 more source

Assessing the Potential of Gallic Acid and Methyl Gallate to Enhance the Efficacy of β-Lactam Antibiotics against Methicillin-Resistant Staphylococcus aureus by Targeting β-Lactamase: In Silico and In Vitro Studies

Antibiotics, 2023
Methicillin-resistant Staphylococcus aureus (MRSA), a global health concern, has prompted research into antibiotic adjuvants as a potential solution. Although our group previously reported the enhancing effects of gallic acid (GA) and methyl gallate (MG)
Pimsumon Jiamboonsri, Chatchakorn Eurtivong, Sompit Wanwong   +2 more
doaj   +1 more source

Could β-Lactam Antibiotics Block Humoral Immunity?

Frontiers in Immunology, 2021
It has been reported that treatment with β-lactam antibiotics induces leukopenia and candidemia, worsens the clinical response to anticancer immunotherapy and decreases immune response to vaccination.
Cléa Melenotte, Cléa Melenotte, Pierre Pontarotti, Pierre Pontarotti, Pierre Pontarotti, Lucile Pinault, Lucile Pinault, Jean-Louis Mège, Jean-Louis Mège, Christian Devaux, Christian Devaux, Christian Devaux, Didier Raoult, Didier Raoult   +13 more
doaj   +1 more source

The Mechanisms of Reactions of β-Lactam Antibiotics [PDF]

, 1987
This chapter explains that penicillin was the first naturally occurring antibiotic to be characterized and used in clinical medicine. It can be seen as the progenitor of the β-lactam family of antibiotics, which are characterized by the possession of the
Michael I. Page, Page, Michael I.
core   +1 more source