Conjugation of Polycationic Peptides Extends the Efficacy Spectrum of β‐Lactam Antibiotics [PDF]
Antibiotic‐resistant enterococci represent a significant global health challenge. Unfortunately, most β‐lactam antibiotics are not applicable for enterococcal infections due to intrinsic resistance.
Julia Werner +20 more
doaj +3 more sources
Effect of β-lactam antibiotics on the gut microbiota of term neonates [PDF]
β-Lactam antibiotics are a class of antibiotics commonly used to treat bacterial infections. However, the effects of β-lactam antibiotics on term neonatal intestinal flora have not been fully elucidated. Hospitalized full-term newborns receiving β-lactam
Hongdan Gu +9 more
doaj +3 more sources
Rapid Detection of Multiple Classes of β-Lactam Antibiotics in Blood Using an NDM-1 Biosensing Assay
Currently, assays for rapid therapeutic drug monitoring (TDM) of β-lactam antibiotics in blood, which might be of benefit in optimizing doses for treatment of critically ill patients, remain challenging.
Qinglai Meng +11 more
doaj +2 more sources
Combatting Pseudomonas aeruginosa with β-Lactam Antibiotics: A Revived Weapon? [PDF]
Pseudomonas aeruginosa is a significant threat to public health as an aggressive, opportunistic pathogen. The use of β-lactam antibiotics such as penicillins, cephalosporins, monobactams, and carbapenems remains a front-line treatment against P ...
Dylan W. Zhao, Christopher T. Lohans
doaj +2 more sources
Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of hospital- and community-associated infections. The formation of adherent clusters of cells known as biofilms is an important virulence factor in MRSA pathogenesis.
Mandy Ng +7 more
doaj +2 more sources
A Spore-Based Biosensor-on-Pillar Platform for Detecting ß-Lactam Antibiotics in Milk [PDF]
Antimicrobial resistance (AMR) is increasingly becoming a major global public health concern, as antibiotics are losing their effectiveness at an alarming rate due to drug resistance.
Sammer UƖ Hassan +4 more
doaj +2 more sources
THE STUDY OF PREVALENCE OF HYPERSENSITIVITY TO Β-LACTAM ANTIBIOTICS AMONG THE POPULATION OF UKRAINE
This article is a part of research project of Ukrainian Medical Stomatological Academy “The Study of the Prevalence of Hypersensitivity to β-Lactam Antibiotics among the Ukrainian Population”, state registration No. 0116U004377.
A.V. Lavrenko, I.P. Kaidashev
doaj +2 more sources
Novel β-lactam antibiotics versus other antibiotics for treatment of complicated urinary tract infections: a systematic review and meta-analysis [PDF]
BackgroundNovel β-lactam antibiotics as well as other kinds of antibiotics have been used to treat complicated urinary tract infections (cUTIs); however, their efficacy and safety remain controversial.ObjectiveWe conducted a systematic review with meta ...
Xiang hua Quan +5 more
doaj +2 more sources
The Secondary Resistome of Methicillin-Resistant Staphylococcus aureus to β-Lactam Antibiotics [PDF]
Background: Therapeutic strategies for methicillin-resistant Staphylococcus aureus (MRSA) are increasingly limited due to the ability of the pathogen to evade conventional treatments such as vancomycin and daptomycin. This challenge has shifted the focus
Nader Abdelmalek +5 more
doaj +2 more sources
Machine learning models for coagulation dysfunction risk in inpatients administered β-lactam antibiotics [PDF]
The β-Lactam antibiotics represent a widely used class of antibiotics, yet the latent and often overlooked risk of coagulation dysfunction associated with their use underscores the need for proactive assessment.
Yuqing Hua +6 more
doaj +2 more sources

