Results 11 to 20 of about 1,201,054 (248)
Rapid Detection of Multiple Classes of β-Lactam Antibiotics in Blood Using an NDM-1 Biosensing Assay
Antibiotics, 2021 Currently, assays for rapid therapeutic drug monitoring (TDM) of β-lactam antibiotics in blood, which might be of benefit in optimizing doses for treatment of critically ill patients, remain challenging.
Qinglai Meng +11 more
doaj +2 more sources
Dose-Response, 2014 Methicillin-resistant Staphylococcus aureus (MRSA) is a leading cause of hospital- and community-associated infections. The formation of adherent clusters of cells known as biofilms is an important virulence factor in MRSA pathogenesis.
Mandy Ng +7 more
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Imide and isatin derivatives as β-lactam mimics of β-lactam antibiotics [PDF]
, 2002 Activated γ-lactams, which are derivatives of succinimide, phthalimide and isatin with suitable elements of molecular recognition, have been synthesised as mimics of the ß-lactam antibiotics and their chemical and biological reactivity ...
Hadfield, Peter S. +4 more
core +5 more sources
Giant linear plasmids of β-lactam antibiotic producing Streptomyces [PDF]
FEMS Microbiology Letters, 1995 A survey of the total cellular DNA from five β-lactam antibiotic-producing Streptomyces spp. by pulsed field gel electrophoresis was conducted to investigate the presence of linear plasmids. Streptomyces clavuligerus NRRL 3585 contained two giant linear plasmids of 120 and 430 kb, in addition to the well-characterized 11.7 kb linear plasmid ...
Donald J. Netolitzky +3 more
openaire +1 more source
A method to transform the β-lactam antibiotic producerStreptomyces wadayamensis [PDF]
FEMS Microbiology Letters, 1986 We have developed a transformation system for Streptomyces wadayamensis, a cephamycin C producer. 1−5 × 109 protoplasts can be obtained when late logarithmic phase cultures of this microorganisms are incubated with 10 mg/ml of lysozyme. Polyethylene glycol-Ca2+-mediated transformation of these protoplasts yielded 106 transformants per μg of pIJ702 or ...
C. Acebal, V. Rubio, G. Márquez
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Spherical and rod shaped protoplasts from β-lactam antibiotic treated cultures of Bacillus subtilis [PDF]
FEMS Microbiology Letters, 1988 Addition of β-lactams to exponentially growing cultures of an autolytically deficient Bacillus subtilis metc3 lyt-2 strain FJ6 caused increase in optical density to stop after 1 h when it had about doubled, and thereafter to remain constant for at least 6 h.
G. Wright, H.J. Rogers
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NMR spectrometric assay for determining enzymatic hydrolysis of β-lactam antibiotics with bacteria in aqueous solution [PDF]
FEMS Microbiology Letters, 1984 An application of a nuclear magnetic resonance (NMR) spectrometer for the measurement of β-lactamase activity in clinical material containing bacteria is presented. By means of proton (1H)-NMR, it was easy to measure quantitatively β-lactamase activity in human bacteriuria, without performing any such pretreatment as isolation of bacteria or extraction
Koji O'hara, Yoko Shiomi, Megumi Kono
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The state and consideration for skin test of β-lactam antibiotics in pediatrics
Frontiers in Cellular and Infection Microbiology, 2023 β-lactam antibiotics are the most frequently used drugs and the most common drugs that cause allergic reactions in pediatrics. The occurrence of some allergic reactions can be predicted by skin testing, especially severe adverse reactions such as ...
Chunhui Gao +3 more
doaj +1 more source
Initiation of murein biosynthesis inEscherichia colicells treated with β-lactam antibiotics [PDF]
FEMS Microbiology Letters, 1987 The study of the synthesis and accumulation of murein in cells initiating growth in the presence of β-lactam antibiotics indicated: (i) Murein rearrangement contributes substantially to cell enlargement during the first doubling in cell mass; (ii) Penicillin-binding protein 2 has the potential capability to synthesize most, if not all, the new murein ...
Antonio G. Pisabarro +3 more
openaire +1 more source
BMC Complementary Medicine and Therapies, 2021 Background β-lactam antibiotics are a class of broad-spectrum antibiotics consisting of all antibiotic agents that contain a β-lactam ring in their molecular structures. β-lactam antibiotics are only known to be isolated from fungi (e.g.
Tiffany Turner +3 more
doaj +1 more source