Results 41 to 50 of about 1,201,054 (248)

Additional file 2: of Treatment of community-onset pneumonia in neutropenic cancer patients: β-lactam monotherapy versus combination antibiotic regimens

, 2019
Table S2.. Multivariate analysis of 90-day all-cause mortality due to neutropenic pneumonia. (DOCX 15 kb)
Seok, Hyeri, Ko, Jae-Hoon, Peck, Kyong, Kim, Ji-Yeon, Lee, Ji, Park, Ga, Cho, Sun, Kang, Cheol-In, Lee, Nam, Chung, Doo   +9 more
openaire   +1 more source

Smart Antibacterial Coatings: Harnessing Bacterial Redox Activity for Infection Control

Advanced Materials Interfaces, EarlyView.
In this study, we have shown that ceftazidime‐loaded poly(3,4‐ethylenedioxythiophene) (PEDOT@CAZ) functions as a smart, redox‐responsive antibacterial coating that couples bacterial electrical activity with localized antibiotic delivery. Shewanella oneidensis and Pseudomonas aeruginosa induced distinct redox responses in PEDOT, reflecting their ...
Abdullah, Szymon Smołka, Kamran Ayaz, Sara Shakibania, Sajida Maryam, Taral Patel, Roman Turczyn, Ewa Zabłocka‐Godlewska, Katarzyna Krukiewicz   +8 more
wiley   +1 more source

Novel β-lactam antibiotics versus other antibiotics for treatment of complicated urinary tract infections: a systematic review and meta-analysis

Frontiers in Pharmacology
BackgroundNovel β-lactam antibiotics as well as other kinds of antibiotics have been used to treat complicated urinary tract infections (cUTIs); however, their efficacy and safety remain controversial.ObjectiveWe conducted a systematic review with meta ...
Xiang hua Quan, Xin yi Wang, Chun hua Han, Xiao min Xing, Bin Zhang, Huai qin Cang   +5 more
doaj   +1 more source

Polychip‐A High‐Throughput Droplet Microfluidics Platform for Interrogating Microbial Interactions

Advanced Science, EarlyView.
Polychip, a fully integrated droplet microfluidics platform, enables high‐throughput, single‐cell resolution screening of polymicrobial interactions. By seamlessly combining six automated microfluidics operations on a single chip, the system accelerates antimicrobial discovery by 11 to 14 times compared to traditional robotic methods.
Jeong Jae Han, Adrian Ryan Guzman, Aifen Zhou, Han Zhang, Rohit Gupte, Haemin Jung, Kaylee Delgado, Sini Skariah, Ali Sultan, Arul Jayaraman, Paul de Figueiredo, Arum Han   +11 more
wiley   +1 more source

Cysteine Thioaldehydes: Photolytic Generation, Reactivity, and Biological Implications

Angewandte Chemie, EarlyView.
Photolysis of cysteine phenacylsulfides bearing non‐conjugating electron‐withdrawing substituents leads to high conversions into cysteine thioaldehydes through a Norrish type‐II pathway. This methodology enabled the study of the aqueous reactivity of these important biosynthetic intermediates, which, depending on peptide sequence, pH and buffer ...
Ardra Karthika, Matthew Murray, Guillermo Palop, Lee‐Ann J. Keane, Patrick McArdle, Nicholas D. J. Yates, Christopher D. Spicer, Alison Parkin, Martin A. Fascione, Eddie L. Myers   +9 more
wiley   +2 more sources

THE STUDY OF PREVALENCE OF HYPERSENSITIVITY TO Β-LACTAM ANTIBIOTICS AMONG THE POPULATION OF UKRAINE

Проблеми екології та медицини, 2018
This article is a part of research project of Ukrainian Medical Stomatological Academy “The Study of the Prevalence of Hypersensitivity to β-Lactam Antibiotics among the Ukrainian Population”, state registration No. 0116U004377.
A.V. Lavrenko, I.P. Kaidashev
doaj   +1 more source

Neo-antigens for the serological diagnosis of IgE-mediated drug allergic reactions to antibiotics cephalosporin, carbapenem and monobactam

Scientific Reports, 2020
New antigens deriving from -lloyl and -llanyl, major and minor determinants, respectively, were produced for β-lactam antibiotics cefuroxime, cefotaxime, ceftriaxone, meropenem and aztreonam.
Edurne Peña-Mendizabal, Sergi Morais, Ángel Maquieira   +2 more
doaj   +1 more source

β-lactam antibiotic versus combined β-lactam antibiotics and single daily dosing regimens of aminoglycosides for treating serious infections: A meta-analysis

, 2019
Background: Combining aminoglycosides with β-lactam antibiotics for treating serious infections has not been associated with reduced mortality in previous meta-analyses.
Roberts, Prof Jason, Grimwood, Keith, Andrews, Katherine, Heffernan, Aaron James, Sime, Fekade Bruck, Sun, Jing, Ellwood, David, Kumar, Anand, Lipman, Prof Jeffrey   +8 more
core   +1 more source

A Comprehensive Microbial Gene Catalog of the Human Airway Microbiome Across Anatomical Sites and Geographic Regions

Advanced Science, EarlyView.
An integrated Human Airway Microbiome Gene Catalog (iHAMGC) is constructed from 12,273 metagenomic airway samples, providing a high‐resolution reference of respiratory microbial genes. The catalog enables systematic exploration of taxonomic and functional variation across airway niches and geographic regions, revealing site‐specific and region ...
Qing Zhang, Dashu Li, Bo Liu, Yue Zhang, Min Li, Ruochun Guo, Yawen Ni, Shibin Chen, Biao Ni, Lijie Qiu, Guorui Xing, He Dong, Qiulong Yan, Shenghui Li, Xiaohui Zou, Bin Cao   +15 more
wiley   +1 more source

Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae

Angewandte Chemie, EarlyView.
The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray, Sohan Hazra, Ryan W. Mull, Erinn M. O'Neill, Bo Li   +4 more
wiley   +2 more sources