Results 201 to 210 of about 86,850 (260)

Strategies Toward Accessing Enantioenriched (Hetero)Benzo‐Fused 5‐ and 6‐ Membered Rings via Intermolecular Carbometalation

Angewandte Chemie, Volume 138, Issue 23, 1 June 2026.
The use of transition‐metal catalysts and design of chiral ligands have allowed chemists to access highly functionalized benzofused 5‐ and 6‐ membered rings in high yield and enantioselectivity. A common strategy used relies on an intermolecular carbometalation across alkynes and olefins, usually followed by a subsequent intramolecular carbometalation.
Clara Jans, Armaan Grewal, Xavier Abel‐Snape, Mark Lautens   +3 more
wiley   +2 more sources

Structural shifts in TolC facilitate Efflux-Mediated β-lactam resistance. [PDF]

Commun Biol
Kantarcioglu I, Gaszek IK, Guclu TF, Yildiz MS, Atilgan AR, Toprak E, Atilgan C.   +6 more
europepmc   +1 more source

Impact of PBP4 Alterations on β-Lactam Resistance and Ceftobiprole Non-Susceptibility Among Enterococcus faecalis Clinical Isolates. [PDF]

Front Cell Infect Microbiol, 2021
Lazzaro LM, Cassisi M, Stefani S, Campanile F.   +3 more
europepmc   +1 more source

Molecular epidemiology and β-lactam resistance mechanisms of <i>Enterobacter cloacae</i> complex isolates obtained from bloodstream infections, Kyoto, Japan. [PDF]

Microbiol Spectr
Matsuo A, Matsumura Y, Mori K, Noguchi T, Yamamoto M, Nagao M.   +5 more
europepmc   +1 more source

Targeting Peptostreptococcus anaerobius with an Iron‐Based Nanozyme Reverses Ferroptosis Resistance and Enhances Antitumor Immunity in Colorectal Cancer

Advanced Science, Volume 13, Issue 35, 24 June 2026.
An iron‐based nanozyme selectively eliminates intratumoral P. anaerobius while catalytically generating ROS to induce ferroptosis, synergistically suppressing colorectal cancer growth and activating anti‐tumor immunity through immunogenic cell death. ABSTRACT The intratumoral microbiota is a critical determinant of therapeutic outcomes in colorectal ...
Yinghao Cao, Jun Wang, Hanwenchen Wang, Xiang Sun, Fang Fang, Shiying Li, Jianping Liu, Changrong Shi, Pengyuan Qi, Jianhua Zou, Xiaoyuan Chen, Kailin Cai   +11 more
wiley   +1 more source

Blue Light Compromises Bacterial β-Lactamases Activity to Overcome β-Lactam Resistance. [PDF]

Lasers Surg Med
Dos Anjos C, Wang Y, Truong-Bolduc QC, Bolduc PK, Liu M, Hooper DC, Anderson RR, Dai T, Leanse LG.   +8 more
europepmc   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

Advanced Science, Volume 13, Issue 33, 15 June 2026.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu, Bayinqiaoge, Xi Lu, Xin Wang, Rongfeng Wang, Yi Li, Shi‐Yang Tang, Chengchen Zhang   +7 more
wiley   +1 more source

The role of Listeria monocytogenes PstA in β-lactam resistance requires the cytochrome bd oxidase activity. [PDF]

J Bacteriol
Tu Z, Stevenson DM, McCaslin D, Amador-Noguez D, Huynh TN.   +4 more
europepmc   +1 more source

Reducing Peptidoglycan Crosslinking by Chemical Modulator Reverts β-lactam Resistance in Methicillin-Resistant Staphylococcus aureus. [PDF]

Adv Sci (Weinh)
Kim JH, Lee Y, Kim I, Chang J, Hong S, Lee NK, Shum D, Baek S, Kim W, Jang S, Lee W.   +10 more
europepmc   +1 more source