Results 181 to 190 of about 86,850 (260)

Induction of AmpC-Mediated β-Lactam Resistance Requires a Single Lytic Transglycosylase in Agrobacterium tumefaciens. [PDF]

Appl Environ Microbiol, 2022
Figueroa-Cuilan WM, Howell M, Richards C, Randich A, Yadav AK, Cava F, Brown PJB.   +6 more
europepmc   +1 more source

Systematic Review of Intravenous Ceftriaxone Administration in Animals

Veterinary Medicine and Science, Volume 12, Issue 4, July 2026.
ABSTRACT Background Ceftriaxone is an antibiotic frequently prescribed in veterinary medical practice due to its effectiveness against several pathogenic microorganisms responsible for diseases in different animal species. Objective To select scientific articles from the academic databases PubMed and Web of Science that analysed the pharmacokinetic ...
Paula Maria Fernandes de Vasconcelos, Gabriel de Brito Rodrigues, Michel Leandro de Campos   +2 more
wiley   +1 more source

Bacteriophage infection drives loss of β-lactam resistance in methicillin-resistant <i>Staphylococcus aureus</i>. [PDF]

Elife
Tran M, Hernandez Viera AJ, Tran PQ, Nilsen ED, Tran L, Mo CY.   +5 more
europepmc   +1 more source

PBP4-mediated β-lactam resistance among clinical strains of Staphylococcus aureus. [PDF]

J Antimicrob Chemother, 2021
Satishkumar N, Alexander JAN, Poon R, Buggeln E, Argudín MA, Strynadka NCJ, Chatterjee SS.   +6 more
europepmc   +1 more source

Phenylalanine Versus Tyrosine (Pos. 367/332 in MCT1/MCT4) in the Substrate Binding Site Defines Affinity and Preferred Directionality of Human Monocarboxylate Transporters 1–4

Acta Physiologica, Volume 242, Issue 7, July 2026.
ABSTRACT Aim Human monocarboxylate transporters 1–4, MCT, are key for the lactate/H+ exchange between glycolytic and oxidative cancer cells, white and red muscle fibers, or in the astrocyte‐neuron shuttle. The common MCT transport mechanism involves three conserved residues, that is, a substrate‐attracting Lys and a conformation‐locking Asp/Arg salt ...
Maike Menzel, Ioana‐Daniela Dumitru, Josh Peters, Jan‐Bernd Hövener, Andrey N. Pravdivtsev, Ana‐Nicoleta Bondar, Eric Beitz   +6 more
wiley   +1 more source

Evolutionary trajectories of β-lactam resistance in Enterococcus faecalis strains. [PDF]

mBio
Ugalde Silva P, Desbonnet C, Rice LB, García-Solache M.   +3 more
europepmc   +1 more source

Usefulness of EUCAST rapid antibiotic susceptibility breakpoints and screening cut-off values directly from blood cultures for the inference of β-lactam resistance mechanisms in Enterobacterales. [PDF]

JAC Antimicrob Resist, 2023
Cerrudo V, Cortés-Cuevas JL, García-Fernández S, Morosini MI, Cantón R, Sánchez-Díaz AM.   +5 more
europepmc   +1 more source

Drugs that act on both G protein‐coupled receptors (GPCRs) and kinases: potentiation of effects, side effects and general aspects of drug pleiotropy

British Journal of Pharmacology, Volume 183, Issue 13, Page 3471-3483, July 2026.
Abstract Background A drug designed for a specific target often interacts with multiple targets, either unintentionally or as part of its intended mechanism of action. This has been called pharmacological pleiotropy or polypharmacology. There are key endogenous ligands such as ATP, GABA and glutamate that act on various proteins in humans. Furthermore,
Hampus Ljunggren, Aleksandr Sokolov, Flavio Ballante, Robert Fredriksson, Francisco Lagunas‐Rangel, Alexander S. Hauser, Stefan Knapp, Jörgen Jonsson, Helgi B. Schiöth   +8 more
wiley   +1 more source

A Circular and Tacticity‐Independent Crystalline Mono‐Substituted Nylon‐6 Platform: Unexpected Large Positional Effects on Crystallizability and Performance

Angewandte Chemie, Volume 138, Issue 25, 15 June 2026.
Methyl substitution positions on the nylon‐6 backbone markedly affect crystallizability, thermomechanical properties, and recyclability of the resulting atactic nylon‐6 variants. While γ‐methyl substitution gives an amorphous nylon, all other four methyl‐substitution positions (α, β, δ, and ε) afford, unexpectedly, crystalline nylons, showing tacticity‐
Jun‐Jie Tian, Jiyun Nam, Lili Wang, Andrea L. Baer, Ruirui Li, Maëlle T. Gace, Wei‐Feng Zheng, Clarissa Lincoln, Nicholas A. Rorrer, Eugene Y.‐X. Chen   +9 more
wiley   +2 more sources

Fecal carriage, transferable β-lactam resistance, and efflux pump contribution in third-generation cephalosporin-resistant <i>Escherichia coli</i> from small-scale farm animals and workers in northern Thailand. [PDF]

Vet World
Tansawai U, Niumsup PR.
europepmc   +1 more source