Filling knowledge gaps related to AmpC-dependent β-lactam resistance in Enterobacter cloacae. [PDF]
Barceló IM +5 more
europepmc +1 more source
Streamlining antibiotic use in community acquired pneumonia: A quality improvement initiative
Visual Abstract Abstract Background Evidence suggests a 3‐day total duration and early transition to oral therapy is safe in hospitalized patients with community acquired pneumonia (CAP)—though such care is not standard in the United States. To implement these evidence‐based practices, a multidisciplinary group led by a hospitalist and antimicrobial ...
Claire E. Ciarkowski +6 more
wiley +1 more source
This study examined the antibiotic susceptibility of Kocuria rhizophila isolated from Salmo munzuricus samples taken from the Munzur River. The isolates are resistant to Penicillin G, moderately susceptible to gentamicin and tetracycline, and highly susceptible to amoxicillin and ampicillin.
Bülent KAR
wiley +1 more source
The Combinational Effect of Enhanced Infection Control Measures and Targeted Clinical Metagenomics Surveillance on the Burden of Endemic Carbapenem and Other β-Lactam Resistance Among Severely Ill Pediatric Patients. [PDF]
Giampani A +5 more
europepmc +1 more source
De novo or Salvage? Nucleotide Availability as a Driver of Bacterial Adaptation and Virulence
Bacterial pathogens survive in different host environments by switching between making nucleotides by de novo synthesis and scavenging them from the host. This flexibility supports growth and virulence making nucleotide metabolism an attractive therapeutic target.
Riya Joshi +2 more
wiley +1 more source
The Spx stress regulator confers high-level β-lactam resistance and decreases susceptibility to last-line antibiotics in methicillin-resistant Staphylococcus aureus. [PDF]
Nielsen TK +12 more
europepmc +1 more source
Dry‐season pollutant concentration drives microbial restructuring in Bangladesh's Shitalakshya River, shifting communities from Myroides to stress‐tolerant genera while enriching metal resistance genes and efflux pumps, revealing non‐antibiotic co‐selection as a key driver of antimicrobial resistance in urban waters.
Muhammad Ehteshamul Haque +3 more
wiley +1 more source
Chlorhexidine gluconate and alexidine potently kill S. mutans, disrupt biofilms, and downregulate virulence genes, yet show moderate cytotoxicity. In contrast, sub‐MIC amoxicillin paradoxically promotes biofilm formation, highlighting the need for targeted antibiofilm therapies. ABSTRACT This study evaluates the antimicrobial and antibiofilm effects of
Hamideh Kamalloo +5 more
wiley +1 more source
Altered PBP4 and GdpP functions synergistically mediate MRSA-like high-level, broad-spectrum β-lactam resistance in <i>Staphylococcus aureus</i>. [PDF]
Lai L-Y +9 more
europepmc +1 more source
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury +3 more
wiley +1 more source

