Results 151 to 160 of about 86,850 (260)

Clinically Relevant β-Lactam Resistance Genes in Wastewater Treatment Plants. [PDF]

Int J Environ Res Public Health, 2022
Waśko I, Kozińska A, Kotlarska E, Baraniak A.   +3 more
europepmc   +1 more source

On the natural and laboratory evolution of an antibiotic resistance gene

, 2008
TEM-1 ß-lactamase is one of the most notorious antibiotic resistance enzymes around. It exists at high frequencies in antibiotic-resistant bacteria around the world and confers resistance to ß-lactam antibiotics, including penicillins (e.g.
Salverda, M.L.M.
core  

β-Lactam Resistance in ESKAPE Pathogens Mediated Through Modifications in Penicillin-Binding Proteins: An Overview. [PDF]

Infect Dis Ther, 2023
Sethuvel DPM, Bakthavatchalam YD, Karthik M, Irulappan M, Shrivastava R, Periasamy H, Veeraraghavan B.   +6 more
europepmc   +1 more source

Institutional Trends in Penicillin Allergy: A New Era of Active Penicillin Allergy Delabeling

Clinical &Experimental Allergy, EarlyView.
Anna Brameli, Allison B. McCoy, Elizabeth McNeer, Leena Choi, Joanna L. Stollings, Grace Koo, Allison E. Norton, Milner Staub, George E. Nelson, James W. Antoon, Sophie E. Katz, Ritu Banerjee, Adam Wright, Elizabeth J. Phillips, Cosby A. Stone Jr.   +14 more
wiley   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

"Golden Era of Antibiotics" - Coming to an end !!!

SRM Journal of Research in Dental Sciences, 2012
Resistance to antibiotics is increasing at an alarming rate. This is due to superbugs, producing heterogenous groups of enzymes, β-lactamases which inactivate β-lactam antibiotics and others as well.
V Vinodhini, T S Subashini, K S Sridevi Sangeetha, R Shivakumar, Nafeesa Iqbal   +4 more
doaj  

YgfB increases β-lactam resistance in Pseudomonas aeruginosa by counteracting AlpA-mediated ampDh3 expression. [PDF]

Commun Biol, 2023
Eggers O, Renschler FA, Michalek LA, Wackler N, Walter E, Smollich F, Klein K, Sonnabend MS, Egle V, Angelov A, Engesser C, Borisova M, Mayer C, Schütz M, Bohn E.   +14 more
europepmc   +1 more source

ARC in Critical Ill OLT Recipients: True Prevalence, Risk Factors, and Impact on Early Aggressive PK/PD Target Non‐Attainment of CI Beta‐Lactam Therapy for Posttransplant Gram‐Negative Infections

Transplant Infectious Disease, EarlyView.
Augmented renal clearance (ARC) represents a quite prevalent condition among critical orthotopic liver transplant recipients (23.2%). ARC is associated with different demographics and clinical features and significantly affects the attainment of aggressive beta‐lactams pharmacokinetic/pharmacodynamic targets despite the administration of standard ...
Milo Gatti, Riccardo De Paola, Matteo Rinaldi, Cristiana Laici, Antonio Siniscalchi, Pierluigi Viale, Federico Pea   +6 more
wiley   +1 more source

The development of non-β-lactam inhibitors of bacterial transpeptidases

β-Lactams, which inhibit bacterial transpeptidases, are currently the most widely used antibacterials globally. The emergence of bacterial resistance, conferred by β- lactamases in particular, which degrade β-lactam antibiotics, poses a perilous threat ...
Suits, Timothy Francis
core   +1 more source

Serious Bacterial Infections in Hospitalized Neonates in Eastern Ethiopia: Investigating the Emerging Pathogen Pantoea dispersa Compared With Klebsiella pneumoniae

Tropical Medicine &International Health, EarlyView.
ABSTRACT Background Serious bacterial infections (SBIs) are major contributors to neonatal morbidity and mortality in low‐income countries. We describe the aetiology and risk factors for neonatal bacteraemia and in‐hospital mortality in eastern Ethiopia, focusing on Pantoea dispersa, a rarely studied pathogen, and Klebsiella pneumoniae.
Yunus Edris, Faisel A. Hassen, Desalegn A. Ayana, Fami Ahmed, Haleluya Leulseged, Dadi Marami, Jabir Aliye, Belete G. Alem, Zelalem T. Mariam, Gezahang Mengesha, Nega Assefa, Alexander M. Aiken, J. Anthony G. Scott, Lola Madrid   +13 more
wiley   +1 more source