Summary Febrile neutropenia causes substantial morbidity in acute myeloid leukaemia and higher risk myelodysplastic syndrome. We aimed to describe current practice and priorities for clinical trials in the prevention and management of febrile neutropenia across Australia/New Zealand (ANZ), the United Kingdom (UK), Canada and Europe.
Aleece MacPhail +14 more
wiley +1 more source
Burkholderia pseudomallei PenI β-lactamase and variants are potently inhibited by taniborbactam. [PDF]
Mojica MF +12 more
europepmc +1 more source
Shifting Antimicrobial Susceptibility Patterns of Uropathogens: A 20‐Year Analysis of Urine Cultures
ABSTRACT Objectives Antimicrobial resistance among uropathogens, particularly extended‐spectrum β‐lactamase (ESBL) production and fluoroquinolone (FQ) resistance, presents a significant challenge to treating urinary tract infections (UTIs). This study aimed to analyze 20‐year trends in antimicrobial susceptibility among key urinary isolates at a single
Shinichi Takebe +6 more
wiley +1 more source
Ceftazidime/avibactam and aztreonam combined with an aminoglycoside combat metallo-β-lactamase-producing <i>Klebsiella pneumoniae</i>. [PDF]
Karunanidhi A +10 more
europepmc +1 more source
ABSTRACT Background Platelet‐rich plasma (PRP) has been widely applied in burn wound management due to its high concentration of bioactive growth factors. However, inconsistent clinical outcomes and the lack of standardized protocols regarding timing, frequency, and leukocyte content limit its broader clinical adoption.
Jian‐Guo Shi +5 more
wiley +1 more source
Comparative analysis of the effects of aztreonam combined with four β-lactamase inhibitors against carbapenem-resistant <i>Enterobacterales</i>. [PDF]
Meng Q +9 more
europepmc +1 more source
This work establishes a newly developed Galleria mellonella infection model as a powerful, ethical platform for studying Bacteroides fragilis pathogenesis and therapy. Leveraging this model, the study identifies MOA4 as a potent BFT‐3 inhibitor that improves host survival, increases bacterial clearance, and synergizes with antibiotics without toxicity.
Ana Jiménez‐Alesanco +6 more
wiley +1 more source
Antibacterial Potential of Actinomycete Extracts and Characterization of β-Lactamase-Producing Multidrug-Resistant Uropathogenic Escherichia coli. [PDF]
Khaledi H, Obeid NO.
europepmc +1 more source
Fluorescent proteins: A journey from the cell to extreme environments in material science
Applications of proteins and microorganisms as tools or effectors in material science. Abstract This review presents the progression from the use of fluorescent proteins (FPs) and chromoproteins as bioimaging labels and sensors to the strategic engineering of their properties for robust functionality in synthetic and non‐biological environments ...
Bianca Menchicchi +3 more
wiley +1 more source
Variations in carbapenem resistance associated with the VIM-1 metallo-β-lactamase across the <i>Enterobacterales</i>. [PDF]
Rondinelli M +5 more
europepmc +1 more source

