Results 181 to 190 of about 762,836 (292)

Study of Streptomyces β-lactamase [PDF]

open access: yes, 1990
β-lactamases play an important part in the resistance of many bacteria to β-lactam antibiotics. This degradative enzyme hydrolyses the amide bond in the β-lactam ring of susceptible penicillins and cephalosporins.
Barallon, Valerie Rita
core  

Table_2_Molecular Characterization of Extended-Spectrum β-Lactamase-Producing Multidrug Resistant Escherichia coli From Swine in Northwest China.docx

open access: yes, 2018
Objectives: The aim of the present study was to explore the prevalence and molecular characterization of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli collected from pig farms in Northwest China.Methods: Between May 2015 and June 2017 ...
Hongchao Zhou (302682)   +6 more
core   +1 more source

A structured, behavioural science approach to the preparation of antimicrobial stewardship interventions for companion animal veterinarians

open access: yesVeterinary Record, Volume 198, Issue 12, Page e521-e532, 13–27 June 2026.
Abstract Background A structured, behavioural science approach was adopted to develop antimicrobial stewardship interventions in UK first‐opinion companion animal veterinary practice. The objectives were to identify behavioural targets for intervention and to understand how practice contexts influence these behaviours.
Ben Walker   +3 more
wiley   +1 more source

Table_1_Molecular Characterization of Extended-Spectrum β-Lactamase-Producing Multidrug Resistant Escherichia coli From Swine in Northwest China.DOCX

open access: yes, 2018
Objectives: The aim of the present study was to explore the prevalence and molecular characterization of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli collected from pig farms in Northwest China.Methods: Between May 2015 and June 2017 ...
Hongchao Zhou (302682)   +6 more
core   +1 more source

Metabolism‐Based Biomarkers for Rapid Phenotypic Antibiotic Susceptibility Testing

open access: yesAdvanced Science, Volume 13, Issue 33, 15 June 2026.
Metabolic differences emerging after antibiotic exposure provide rapid phenotypic signals of susceptibility and resistance. This review summarizes metabolic biomarkers for rapid phenotypic AST, associated with nutrient uptake, respiratory activity, metabolic reprogramming, and enzymatic function. ABSTRACT The accelerating global crisis of antimicrobial
Sha Yu   +7 more
wiley   +1 more source

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1833-1844, June 2026.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti   +9 more
wiley   +1 more source

Highly Sensitive In Vivo Imaging of Bacterial Infections with a Hydrophilicity‐Switching, Self‐Immobilizing, Near‐Infrared Fluorogenic β‐Lactamase Probe Enriched within Bacteria

open access: yesAdvanced Science
The emergence of antibiotic resistance, particularly bacterial resistance to β‐lactam antibiotics, the most widely prescribed therapeutic agents for infectious diseases, poses a significant threat to public health worldwide.
Fangfang Chen   +6 more
doaj   +1 more source

Epidemiologia molecolare di Klebsiella pneumoniae produttore di beta-lattamasi ad ampio spettro (ESBL) circolante in una Terapia Intensiva Neonatale

open access: yes, 2006
The molecular epidemiology of extended-spectrum beta-lactamase (ESBL)-producing Klebsiella pneumoniae was investigated in the neonatal intensive care unit (NICU) of a university hospital in Italy from September 2002 to December 2004, when 233 ...
Bagattini, Maria
core  

Fusobacterium nucleatum in cancer: Interactions with microbiota, tumour colonisation and cancer progression

open access: yesClinical and Translational Medicine, Volume 16, Issue 6, June 2026.
F. nucleatum colonises tumours through mucosal translocation, adjacent‐tissue migration and hematogenous dissemination. It promotes cancer progression via adhesion, inflammation, immune evasion, epigenetic remodelling and metastasis. Its effects on therapy response are tumour‐context dependent. Microbiome‐guided targeting may enable precision oncology.
Feng Zhao   +7 more
wiley   +1 more source

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