Results 221 to 230 of about 935,518 (288)

Investigating enzyme function by geometric matching of catalytic motifs

Protein Science, Volume 35, Issue 9, September 2026.
Abstract The rapidly growing universe of predicted protein structures offers opportunities for data driven exploration but requires computationally scalable and interpretable tools. We developed a method to detect catalytic features in protein structures, providing insights into enzyme function and mechanism.
Raymund E. Hackett, Ioannis G. Riziotis, Martin Larralde, António J. M. Ribeiro, Georg Zeller, Janet M. Thornton   +5 more
wiley   +1 more source

Rising Incidence of New Delhi Metallo-β-Lactamase-Producing Carbapenem-Resistant Enterobacterales, 10 US Sites, 2018-2023. [PDF]

Open Forum Infect Dis
Duffy N, Campbell D, Li R, Brandenburg J, Ansari U, Kent AG, Nadle J, Hoetzer K, Johnston H, Driscoll J, Czaja C, Maloney M, Jacob JT, Smith G, Vaeth E, Wilson LE, Tourdot L, Gross A, Malley SO, Lynfield R, Dumyati G, Looi HC, Tellerman J, Hoffman MR, Flores KG, Hertzel H, Muleta D, Wilson CD, Karlsson M, Gargis AS, Guh AY.   +30 more
europepmc   +1 more source

mcr‐Mediated Colistin Resistance in Escherichia coli: A One Health Review of Reported Prevalence Across Human, Animal, Food, and Environmental Sectors

Public Health Challenges, Volume 5, Issue 3, September 2026.
This One Health review maps the global prevalence of mcr‐mediated colistin resistance in Escherichia coli across human, animal, food, and environmental sectors. By tracking datasets across diverse geographic regions, the study highlights critical resistance hotspots, emphasizing the urgent need for integrated cross‐sectoral surveillance to limit global
Ferdous‐Ul‐Haque Joy, Tashfiya Zaman Mouree, Munny Das, Asma Kabir   +3 more
wiley   +1 more source

Free-ranging hedgehogs as sentinels of environmental extended-spectrum β-lactamase-producing Enterobacterales. [PDF]

One Health
Daniels TZ, Eshar D, Aharon Y, Amit S.
europepmc   +1 more source

Antibacterial Effect of the In Vitro Interaction Between Clotrimazole and Chlorhexidine Against Staphylococcus pseudintermedius With Known Resistance Patterns Isolated From Canine Pyoderma

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
The 2:1 chlorhexidine–clotrimazole combination demonstrated enhanced antibacterial activity against canine Staphylococcus pseudintermedius isolates, including resistant strains. Reduced MIC values, predominantly additive interactions and absence of antagonism support its use as a promising topical strategy for canine pyoderma management.
Brenda Gallegos‐Torres, Edgar Alfonseca‐Silva, Claudia Ledesma‐Carrasco, Itzcoatl Aquino‐Díaz   +3 more
wiley   +1 more source

Metagenomics Reveals Microbial Community Shifts Associated With Contrasting Anthropogenic Impacts in Freshwater Sources of A Coastal Protected Area in Southeastern Brazil

Water Environment Research, Volume 98, Issue 9, September 2026.
Metagenomics revealed distinct anthropogenic signatures in the microbiome of freshwater sources on Marambaia Island, supported by the Anthropogenic Impact Index (AII). Impacted sites showed lower microbial diversity, enrichment of fecal‐associated taxa, and 14 antimicrobial resistance genes, whereas conductivity, salinity, and turbidity explained 88.1%
Bruna Barbosa de Paula, Marize Pereira Miagostovich, Camille Ferreira Mannarino, André Vinicius Costa Ribeiro, Natália Maria Lanzarini, Carla Santos de Oliveira, Shênia Patrícia Corrêa Novo   +6 more
wiley   +1 more source

Structural perspectives on clinical β-lactamase inhibitors: From mechanism to resistance. [PDF]

J Microbiol
Park SB, Kim MY, Cha SS.
europepmc   +1 more source

Prevalence and Genomic Characterization of mcr‐Positive Enterobacteriaceae in Retail Meat in Thailand Following the Colistin Ban

Microbiology and Immunology, Volume 70, Issue 9, Page 402-415, September 2026.
ABSTRACT This study aimed to investigate the prevalence and characteristics of mcr‐positive Enterobacteriaceae in retail meat in Thailand following the national ban on prophylactic colistin use in food producing animals. A total of 152 meat samples (103 chicken and 49 pork) were collected from supermarkets and open markets between July and September ...
Ahmed Abououf, Sharda Prasad Awasthi, Asmaa M. Elbastawesy, Noritoshi Hatanaka, Atsushi Hinenoya, Srinuan Somroop, Yukihiro Kaneko, Shinji Yamasaki   +7 more
wiley   +1 more source

NCY-1 β-Lactamase Activity Correlates With Antimicrobial Susceptibility of a Clinical Strain of Nocardia cyriacigeorgica. [PDF]

Microbiologyopen
Couston J, Le Marchand A, Hodille E, Genestet C, Joannard B, Feuillard J, Benito Y, Dumitrescu O, Blaise M.   +8 more
europepmc   +1 more source

A Four‐Center Study on the Activity of Aztreonam and Aztreonam‐Avibactam Combination Against Clinical Isolates of Gram‐Negative Bacilli Producing Representatives of Ambler Class A, B, C or D β‐Lactamases

APMIS, Volume 134, Issue 9, September 2026.
ABSTRACT We aimed to investigate the activity of aztreonam and aztreonam‐avibactam combination against gram‐negative bacilli producing different types of β‐lactamases. Activity of aztreonam and aztreonam‐avibactam against 166 isolates (33 AmpC‐producing, 33 ESBL‐producing, 66 carbapenemase‐producing Enterobacterales, 34 metallo‐β‐lactamase‐producing P.
Gizem İnce Ceviz, Hasan Cenk Mirza, Aylin Üsküdar Güçlü, Özlem Öğüç Şanlı, Özlem Kurt Azap, Banu Sancak, Elvan Hortaç İştar, Ahmet Başustaoğlu   +7 more
wiley   +1 more source