Results 171 to 180 of about 1,489,579 (226)

β-Lactam/β-Lactamase Inhibitor Combinations in Sepsis-Associated Acute Kidney Injury and Renal Replacement Therapy. [PDF]

Antibiotics (Basel)
Lacquaniti A, Pistolesi V, Smeriglio A, Santoro D, Iannetti C, Lentini G, Chimenz R, Chirico V, Trombetta D, Morabito S, Monardo P.   +10 more
europepmc   +1 more source

Restoring Meropenem Activity Against VIM‐1‐Producing Klebsiella pneumoniae Through Zinc‐Binding Ligands

ChemBioChem, Volume 27, Issue 16, 27 August 2026.
Approved zinc‐binding drugs and newly synthesized HisPyr ligands were evaluated as adjuvants to meropenem against metallo‐β‐lactamase‐producing Klebsiella pneumoniae. Chlorpropamide and D‐penicillamine restored meropenem activity against the VIM‐1‐producing strain, while computational analyses supported interactions with the enzyme's binuclear zinc ...
Chiara Ragusa, Ruqaiya Khalil, Valentina Giglio, Kaveh Eskandari, Fraser J. Scott, Attilio V. Vargiu, Graziella Vecchio   +6 more
wiley   +1 more source

Evaluation of Phenotypic and Genotypic Susceptibility Testing Methods for Newer β-lactam/β-lactamase Inhibitor Combinations in Multidrug Resistant Pseudomonas aeruginosa. [PDF]

J Infect Dis
Hall CW, Waglechner N, Choi E, Aftanas P, Katz K, Vermeiren C, Maguire F, Kozak R, Li XX.   +8 more
europepmc   +1 more source

Disarming carbapenemase-producing <i>Acinetobacter baumannii</i>: high potency of the novel therapeutic combination of meropenem and the innovative diazabicyclooctane β-lactamase inhibitor pilabactam (formerly ANT3310). [PDF]

Antimicrob Agents Chemother
Rodríguez-Pallares S, Outeda-García M, Lence E, Rodríguez-Coello A, González-Pinto L, Guijarro-Sánchez P, Báez-Barroso GA, Blanco-Martín T, Vázquez-Ucha JC, Llanos A, Sannio F, Docquier J-D, Morrisey I, Hawser S, Zalacain M, Lemonnier M, González-Bello C, Bou G, Beceiro A, Arca-Suárez J.   +19 more
europepmc   +1 more source

Antimicrobial susceptibility of Enterobacterales causing infection in the elderly: focus on aztreonam-avibactam and recently approved β-lactamase inhibitor combinations. [PDF]

JAC Antimicrob Resist
Sader HS, Mendes RE, Kimbrough JH, Papp-Wallace KM, Winkler ML, Castanheira M.   +5 more
europepmc   +1 more source

<i>In vivo</i> evolution of resistance to contemporary β-lactam/β-lactamase inhibitor combinations during treatment of a KPC-producing <i>Serratia marcescens</i> infection. [PDF]

Antimicrob Agents Chemother
Bailey DC, Castañeda-Barba S, Barry KE, Treerat P, Crawford MA, Hughes MA, Mathers AJ.   +6 more
europepmc   +1 more source

The role of β-lactam/β-lactamase inhibitor combinations in multidrug-resistant bacterial infections: a comprehensive meta-analysis. [PDF]

Am J Transl Res
Wu F, Liu Q, Hu P, Wu C.
europepmc   +1 more source

Emergence of resistance to novel β-lactam/β-lactamase inhibitor combinations in KPC-producing Klebsiella pneumoniae: clinical and genomic insights from consecutive bloodstream infections. [PDF]

Infection
Boattini M, Comini S, Ricciardelli G, Pastrone L, Casale R, Guarrasi L, Cavallo R, Costa C, Gaibani P, Bianco G.   +9 more
europepmc   +1 more source

Combinations comprising dual β-lactams and a β-lactamase inhibitor achieve optimal synergistic inhibition of <i>Mycobacterium abscessus</i> growth. [PDF]

Antimicrob Agents Chemother
Rimal B, Xie Y, Panthi CM, Devlin KL, Beatty KE, Lamichhane G.   +5 more
europepmc   +1 more source

Emerging resistance to novel β-lactam β-lactamase inhibitor combinations in Klebsiella pneumoniae bearing KPC variants. [PDF]

J Glob Antimicrob Resist
Hamza M, Traglia GM, Maccari L, Gomez S, Sanz MB, Akhtar U, Mezcord V, Escalante J, Corso A, Rodriguez C, Bethel CR, Rao GG, Tolmasky ME, Paterson D, Bonomo RA, Pasteran F, Ramirez MS.   +16 more
europepmc   +1 more source