Results 31 to 40 of about 1,471,936 (197)

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

Effect of β-Lactamase inhibitors on in vitro activity of β-Lactam antibiotics against Burkholderia cepacia complex species

Antimicrobial Resistance and Infection Control, 2016
Background Bacteria belonging to the Burkholderia cepacia complex (Bcc) are an important cause of chronic respiratory tract infections in cystic fibrosis patients.
Annelien Everaert, Tom Coenye
doaj   +1 more source

Supra and subgingival application of antiseptics or antibiotics during periodontal therapy

Periodontology 2000, EarlyView., 2023
Abstract Periodontal diseases (gingivitis and periodontitis) are characterized by inflammatory processes which arise as a result of disruption of the balance in the oral ecosystem. According to the current S3 level clinical practice guidelines, therapy of patients with periodontitis involves a stepwise approach that includes the control of the patient ...
Elena Figuero, Jorge Serrano, Nicole Birgit Arweiler, Thorsten Mathias Auschill, Ali Gürkan, Gülnur Emingil   +5 more
wiley   +1 more source

Isothermal Titration Calorimetric Studies of Complexation Reactions [PDF]

The objective of this work has been to study the binding of metal ions to complex ligands expressing two or more metal binding sites, in terms of the thermodynamics of the binding events, and to use this information to contribute to the understanding of ...
Motara, Hasina
core   +3 more sources

Management of clinical infections of Escherichia coli by new β-lactam/ β-lactamase inhibitor combinations

Iranian Journal of Microbiology, 2022
Background and Objectives: Escherichia coli (E. coli) is an important member of Enterobacteriaceae family involved in severe infections. The increased rate of resistance towards different classes of antibiotics limits their treatment options. The aim of
Ashraf Ahmed Kadry, May Ayman El-Antrawy, Amira Mohammed El-Ganiny   +2 more
doaj   +1 more source

Quantitative Insights Into β-Lactamase Inhibitor’s Contribution in the Treatment of Carbapenemase-Producing Organisms With β-Lactams

Frontiers in Microbiology, 2021
Objectives: Carbapenemase-producing organisms (CPOs) are associated with high mortality rates. The recent development of β-lactamase inhibitors (BLIs) has made it possible to control CPO infections safely and effectively with β-lactams (BLs).
Yanfang Feng, Arend L. de Vos, Arend L. de Vos, Shakir Khan, Shakir Khan, Mary St. John, Mary St. John, Tayyaba Hasan, Tayyaba Hasan   +8 more
doaj   +1 more source

β-Lactamases and β-Lactamase Inhibitors in the 21st Century [PDF]

, 2019
The β-lactams retain a central place in the antibacterial armamentarium. In Gram-negative bacteria, β-lactamase enzymes that hydrolyze the amide bond of the four-membered β-lactam ring are the primary resistance mechanism, with multiple enzymes ...
Tooke, Catherine, Colenso, Charlotte K., Hirvonen, Viivi, Spencer, James, Takebayashi, Yuiko, Hinchliffe, Philip, Bragginton, Eilis   +6 more
core   +1 more source

High colonization rates of extended-spectrum β-lactamase (ESBL)-producing Escherichia coli [PDF]

, 2014
BACKGROUND International travel contributes to the worldwide spread of multidrug resistant Gram-negative bacteria. Rates of travel-related faecal colonization with extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae vary for different ...
Battegay, Manuel, Widmer, Andreas F., Andreas Neumayr, Frei, Reno, Neumayr, Andreas, Hatz, Christoph, Jaeger, Veronika K., Veronika K Jaeger, Johannes Blum, Sabine Haller, Andreas F Widmer, Susan DeCrom, Blum, Johannes, Reno Frei, Furrer, Hansjakob, Endimiani, Andrea, Hansjakob Furrer, DeCrom, Susan, Jaeger, Veronika K, Haller, Sabine, Manuel Battegay, Andrea Endimiani, Esther Kuenzli, Widmer, Andreas F, Christoph Hatz, Kuenzli, Esther   +25 more
core   +3 more sources

Broad antibiotic resistance profile of the subclass B3 metallo-β-lactamase GOB-1, a di-zinc enzyme. [PDF]

, 2011
peer reviewedThe metallo-β-lactamase (MBL) GOB-1 was expressed via a T7 expression system in Escherichia coli BL21(DE3). The MBL was purified to homogeneity and shown to exhibit a broad substrate profile, hydrolyzing all the tested β-lactam compounds ...
Nathalie Selevsek, Carine Bebrone, Louise E. Horsfall, Lassaux, Patricia, Benoit M. R. Liénard, Kurt M. Hoffmann, Hoffmann, Kurt, Poirel, Laurent, Michael B. Kupper, Horsfall, Louise E., Horsfall, Louise E.; id_orcid, Bebrone, Carine, Izougarhane, Youssef, Jean-Marie Frère, Lienard, Benoit M. R., Youssef Izougarhane, Selevsek, Nathalie, Kupper, Michael B., Patricia Lassaux, Kupper, Michaël, Horsfall, Louise, Laurent Poirel, Liénard, Benoit, Galleni, Moreno, Frère, Jean-Marie, Hoffmann, Kurt M., Moreno Galleni   +26 more
core   +1 more source

Reduced susceptibility mechanism to cefiderocol, a siderophore cephalosporin, among clinical isolates from a global surveillance programme (SIDERO-WT-2014)

Journal of Global Antimicrobial Resistance, 2020
Objective: To investigate possible mechanistic factors to explain cefiderocol (CFDC) non-susceptibility, we characterized 38 clinical isolates with a CFDC minimum inhibitory concentration (MIC) of >4 μg/mL from a multi-national surveillance study ...
Naoki Kohira, Meredith A. Hackel, Yoshino Ishioka, Miho Kuroiwa, Daniel F. Sahm, Takafumi Sato, Hideki Maki, Yoshinori Yamano   +7 more
doaj   +1 more source