Results 151 to 160 of about 740,410 (298)

Decreased affinity of a penicillin-binding protein for β-lactam antibiotics in a clinical isolate ofStaphylococcus aureusresistant to methicillin [PDF]

FEMS Microbiology Letters, 1981
Michael V. Hayes, Nigel A.C. Curtis, Anne W. Wyke, J. Barrie Ward   +3 more
openaire   +1 more source

Genomic Insights Into Spatiotemporal Dynamics of Acquired Azithromycin Resistance Genes in Salmonella Strains Worldwide

Food Safety and Health, EarlyView.
ABSTRACT Azithromycin has been used for clinical invasive infections caused by fluoroquinolone‐ and third‐generation cephalosporin‐resistant Salmonella, and mass drug administration with azithromycin has been used to reduce under‐5 mortality in children in some countries.
Yuhang Pei, Mengqi Qu, Ziru Yang, Xuebin Xu, Yanan Wang   +4 more
wiley   +1 more source

Synthesis of Novel Bis-β-lactams

, 2012
This study presents the synthesis and structure of newly discovered β-lactams and the mechanism of their synthesis via the Staudinger reaction. β-lactams known as 2-azetidinones, are four membered cyclic amides that have been extensively used and ...
Marquez, Jocabed
core  

Metal-Promoted Allylation, Propargylation, or Allenylation of Azetidine-2,3-diones in Aqueous and Anhydrous Media. Application to the Asymmetric Synthesis of Densely Functionalized 3-Substituted 3-Hydroxy-β-lactams

, 2016
Metal-mediated carbonyl allylation, allenylation, and propargylation of optically pure azetidine-2,3-diones were investigated in both anhydrous and aqueous environments.
Benito Alcaide (1554658), Cristina Aragoncillo (1771678), Pedro Almendros (1554667), Raquel Rodríguez-Acebes (2647213)   +3 more
core   +1 more source

Antimicrobial Sensitivity Profile and Resistance Gene Research in Escherichia coli Isolated From Water and Fish From Lagoa da Conceição, Florianópolis, SC, Brazil

Food Safety and Health, EarlyView.
This paper highlights a concerning scenario of environmental contamination by multidrug‐resistant bacteria, underscoring the need for integrated surveillance and control strategies to address antimicrobial resistance in aquatic environments within the context of One Health.
Francisco Lucas de Amorim Nascimento, Luan Amaral Alexandre, Cynthia Farias Manassi, Alice Cristina da Silva, Luísa Aimée Schmitt Lobe, Gustavo Rocha, Mateus Rocha Ribas, Victor Wolleck, Gabriele Caroline Gottschalk de Abreu, Alessandra Valéria Vortmann, Sheila Mello da Silveira, Rodrigo Barcellos Hoff, Jussara Kasuko Palmeiro, Silvani Verruck   +13 more
wiley   +1 more source

Antimicrobial susceptibility and resistance mechanisms to antipseudomonal β-lactams in Pseudomonas aeruginosa isolates from blood

Microbiology Spectrum
Bloodstream infection caused by Pseudomonas aeruginosa with antimicrobial resistance can be difficult to treat. Herein, we investigated antimicrobial susceptibility to major antipseudomonal β-lactams and analyzed the relationship between resistance ...
Mika Murata, Kosuke Kosai, Fujiko Mitsumoto-Kaseida, Norihito Kaku, Hiroo Hasegawa, Koichi Izumikawa, Hiroshi Mukae, Katsunori Yanagihara   +7 more
doaj   +1 more source

Stereoselective synthesis of constrained norbornane-derived spiro-β-lactams

, 2013
New enantiopure polycyclic norbornane-derived spiro-β-lactams were synthesized by means of a Staudinger ketene-imine reaction between unsymmetrical bicyclic chiral ketenes, generated from differently substituted norbornane carboxylic acids, and (E)-N ...
C. La Rosa, G. Cremonesi, A. Forni, P. Dalla Croce   +3 more
core   +1 more source

Antibiotic Remodeling of the Gut Microbiota Impairs Host Resistance to Secondary Infection

iMetaMed, EarlyView.
Gut microbial dynamics induced by four antibiotics, revealed distinct taxonomic and functional shifts. Vancomycin‐perturbed bacteriomes were proven to promote pathogen resistance to antibiotic treatment. Metronidazole‐treated mice showed pronounced Salmonella translocation to hepatic tissue, and altered Enterococcus avium populations modulated host ...
Miaoyu Li, Ying Chen, Xi Chen, Weili Lu, Jie Liao, Jiaqi Wang, Qiwei Liu, Yanzi Chang, Zeping Xu, Yanye Tu, Yang Zhou, Jing Xue, Binbin Wang, Kang Chen, Keyun Cheng, Chunlai Zeng, Hong Li, Qing Shen   +17 more
wiley   +1 more source

The First Intermolecular Friedel−Crafts Acylation with β-Lactams

, 2016
The first intermolecular Friedel−Crafts acylation of a variety of aromatic substrates with azetidinones is described. The Friedel−Crafts acylations are performed under very mild conditions, using trifluoromethanesulfonic acid to produce β-amino aromatic ...
Jetze J. Tepe (1676119), Kevin W. Anderson (2431894)   +1 more
core   +1 more source

Evaluation of Ceftriaxone as a Monotherapy and Amoxicillin With Clavulanic Acid as Combination Therapy in Surgical Prophylaxis

iNew Medicine, EarlyView.
ABSTRACT Surgical antibiotic prophylaxis (SAP) is crucial in preventing postoperative surgical site infections (SSIs), especially in clean and clean‐contaminated surgeries. It was a prospective comparative observational study that compared the effectiveness and safety of single‐dose ceftriaxone monotherapy with amoxicillin–clavulanic acid as a ...
Anayat Ullah, Arsh Ali, Md Nematullah, Suriya Kumar Singh, Anant Singh Paliwal, Najish Parveen   +5 more
wiley   +1 more source