Results 141 to 150 of about 38,167 (247)

Nasopharyngeal microbiome and resistome profiles in dairy calves fed milk replacer with low-level β-lactams. [PDF]

JDS Commun
Cioletti G, Kenney S, Hovingh E, Springer H, Haley BJ, Ganda E.   +5 more
europepmc   +1 more source

Boronic Acid Inhibitors of β‐Lactamases: A Promising Strategy Against Antimicrobial Resistance

Medicinal Research Reviews, EarlyView.
ABSTRACT The rise of antimicrobial resistance (AMR) poses a critical threat to global health, mostly due to the proliferation of β‐lactamases, a class of enzymes responsible for the inactivation of β‐lactam antibiotics. Among the most promising strategies to restore β‐lactam efficacy is the use of β‐lactamase inhibitors (BLIs), with boronic acid ...
Nicolò Santi, Federico Corsini, Robert A. Bonomo, Emilia Caselli, Fabio Prati   +4 more
wiley   +1 more source

Photochemical Cyclization of Tertiary Buta-2,3-dienamides to β-Lactams Upon Triplet Energy Transfer. [PDF]

Angew Chem Int Ed Engl
Hofer J, Bertrams MS, Kerzig C, Bach T.
europepmc   +1 more source

Mechanistic insights into HipA‐mediated bacterial persistence: Role of initial cellular states and toxin expression kinetics

mLife, EarlyView.
Abstract Persistent bacteria subpopulations showing multidrug tolerance pose significant challenges to antibiotic therapy. While the HipBA toxin–antitoxin (TA) system is known to play a role in persister formation, existing studies predominantly focus on its kinase activity and intracellular regulatory pathways, with limited attention to the ...
Jing Zhao, Yixiao Xiong, Hongxia Zhao, Jin Wang, Xiaona Fang   +4 more
wiley   +1 more source

Lanthipeptides from <i>Chitinophaga pinensis</i> re-potentiating β-lactams against metallo-β-lactamase-producing Enterobacterales <i>in vitro</i>. [PDF]

Microbiol Spectr
Lambropoulou A, Herrmann J, Deschner F, Müller R, Kotsakis SD.   +4 more
europepmc   +1 more source

Toward a Better Understanding of Fatty Acid Amide Hydrolase Inhibition by β-Lactams. [PDF]

Chem Biodivers
Morelle A, Dechenne J, Caruano J, Vander Auwera O, Barozzino-Consiglio G, Michaux C, Muccioli GG, Robiette R.   +7 more
europepmc   +1 more source

ISAba1‐mediated crp‐osmC amplification enhances host‐associated fitness in Acinetobacter baumannii

mLife, EarlyView.
Abstract Acinetobacter baumannii is a pathogen, highly adaptable to both hospital‐ and host‐associated environments. Understanding the genetic mechanisms underlying its adaptability is critical for controlling its persistence. Our study identified the crp‐osmC gene cluster, flanked by ISAba1 elements, as a significant genetic structure undergoing ...
Da‐Wei Wei, Jiangqing Huang, Hailing Fang, Xinyu Wang, Gang Zhang, Chao Wang, Yuqin Song, Jie Feng   +7 more
wiley   +1 more source

Beyond β-Lactams: Defining the Role of Eravacycline in Multidrug-Resistant and Metallo-β-Lactamase-Producing Infections. [PDF]

Antibiotics (Basel)
Keck JM.
europepmc   +1 more source

Time‐Resolved Effects of Cold Atmospheric Plasma on E. coli GW‐AmxH19 Transcriptome and Proteome in an Emulated Wastewater Environment

PROTEOMICS, EarlyView.
ABSTRACT Cold atmospheric plasma (CAP) is effective against a variety of microorganisms. Here, we described effects on an Escherichia coli strain isolated from hospital wastewater caused by treatment with physical plasma. E. coli GW‐AmxH19 was incubated in artificial wastewater and treated for 15 min with CAP.
Jörg Bernhardt, Dominik Schneider, Julia Rielicke, Susanne Sievers, Veronika Hahn, Mechthild Bömeke, Anja Poehlein, Dirk Albrecht, Juergen F. Kolb, Katharina Riedel, Rolf Daniel, Daniela Zühlke   +11 more
wiley   +1 more source

Potentiation of Penicillin G and Selected β-Lactams with Quercetin Against Multidrug-Resistant Bacteria: Mechanistic Insights, Antibacterial Phytochemicals, and Toxicity Evaluation. [PDF]

Int J Mol Sci
Tiwana G, Cock IE, Cheesman MJ.
europepmc   +1 more source