Results 11 to 20 of about 1,666,677 (276)
A method to transform the β-lactam antibiotic producerStreptomyces wadayamensis [PDF]
FEMS Microbiology Letters, 1986 We have developed a transformation system for Streptomyces wadayamensis, a cephamycin C producer. 1−5 × 109 protoplasts can be obtained when late logarithmic phase cultures of this microorganisms are incubated with 10 mg/ml of lysozyme. Polyethylene glycol-Ca2+-mediated transformation of these protoplasts yielded 106 transformants per μg of pIJ702 or ...
C. Acebal, V. Rubio, G. Márquez
openaire +1 more source
Identification of the Extracytoplasmic Function σ Factor σP Regulon in Bacillus thuringiensis
mSphere, 2022 Bacillus thuringiensis and other members of the Bacillus cereus family are resistant to many β-lactams. Resistance is dependent upon the extracytoplasmic function sigma factor σP.
Theresa D. Ho +4 more
doaj +1 more source
Spherical and rod shaped protoplasts from β-lactam antibiotic treated cultures of Bacillus subtilis [PDF]
FEMS Microbiology Letters, 1988 Addition of β-lactams to exponentially growing cultures of an autolytically deficient Bacillus subtilis metc3 lyt-2 strain FJ6 caused increase in optical density to stop after 1 h when it had about doubled, and thereafter to remain constant for at least 6 h.
G. Wright, H.J. Rogers
openaire +1 more source
Initiation of murein biosynthesis inEscherichia colicells treated with β-lactam antibiotics [PDF]
FEMS Microbiology Letters, 1987 The study of the synthesis and accumulation of murein in cells initiating growth in the presence of β-lactam antibiotics indicated: (i) Murein rearrangement contributes substantially to cell enlargement during the first doubling in cell mass; (ii) Penicillin-binding protein 2 has the potential capability to synthesize most, if not all, the new murein ...
Antonio G. Pisabarro +3 more
openaire +1 more source
Stereoselective cyanation of 4-formyl and 4-imino-?-lactams: application to the synthesis of polyfunctionalized ?-lactams [PDF]
Tetrahedron, 2012 Peer ...
Alcaide, Benito +3 more
openaire +2 more sources
mBio, 2020 Poor penetration through the outer membrane (OM) of Gram-negative bacteria is a major barrier of antibiotic development. While β-lactam antibiotics are commonly used against Klebsiella pneumoniae and Enterobacter cloacae, there are limited data on OM ...
Tae Hwan Kim +19 more
doaj +1 more source
NMR spectrometric assay for determining enzymatic hydrolysis of β-lactam antibiotics with bacteria in aqueous solution [PDF]
FEMS Microbiology Letters, 1984 An application of a nuclear magnetic resonance (NMR) spectrometer for the measurement of β-lactamase activity in clinical material containing bacteria is presented. By means of proton (1H)-NMR, it was easy to measure quantitatively β-lactamase activity in human bacteriuria, without performing any such pretreatment as isolation of bacteria or extraction
Koji O'hara, Yoko Shiomi, Megumi Kono
openaire +1 more source
β-lactam Resistance in Pseudomonas aeruginosa: Current Status, Future Prospects
Pathogens, 2021 Pseudomonas aeruginosa is a major opportunistic pathogen, causing a wide range of acute and chronic infections. β-lactam antibiotics including penicillins, carbapenems, monobactams, and cephalosporins play a key role in the treatment of P.
Karl A. Glen, Iain L. Lamont
doaj +1 more source
New Carbapenemase Inhibitors: Clearing the Way for the β-Lactams
International Journal of Molecular Sciences, 2020 Carbapenem resistance is a major global health problem that seriously compromises the treatment of infections caused by nosocomial pathogens. Resistance to carbapenems mainly occurs via the production of carbapenemases, such as VIM, IMP, NDM, KPC and OXA,
J. C. Vázquez-Ucha +3 more
semanticscholar +1 more source
F1000Research, 2021 Background: Worldwide, chicken meat is widely consumed due to its low cost, high nutritional value and non-interference with religious or cultural beliefs.
Erika Rodríguez Cavallo +3 more
doaj +1 more source