Results 21 to 30 of about 740,410 (298)
The Mechanisms of Catalysis by Metallo β-Lactamases [PDF]
, 2008 Class B β-lactamases or metallo-β-lactamases (MBLs) require zinc ions to catalyse the hydrolysis of β-lactam antibiotics such as penicillins, cephalosporins, carbapenems, and cephamycins.
Michael I. Page +3 more
core +1 more source
New Microbes and New Infections, 2019 We report a case of hospital-acquired pneumonia that to our knowledge is the first description in Egypt of the emergence of vancomycin (VA)-resistant Staphylococcus aureus due to the concomitant use of β-lactams.
A.E. Taha +3 more
doaj +1 more source
Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2021 In this work, the stereospecific synthesis of optically active cis β-lactams under diverse microwave-induced conditions using diverse solvents was reported.
Aparna Das +2 more
doaj +1 more source
MicrobiologyOpen, 2020 Methicillin‐resistant Staphylococcus aureus (MRSA) is resistant to most β‐lactams due to the expression of an extra penicillin‐binding protein, PBP2a, with low β‐lactam affinity.
Marte Ekeland Fergestad +5 more
doaj +1 more source
Salicylate decreases production of AmpC type β-lactamases and increases susceptibility to β-lactams in aMorganella morganiiclinical isolate [PDF]
FEMS Microbiology Letters, 2004 The effect of salicylate, a marRAB inducer, on the resistance to β-lactams was characterized in an AmpC β-lactamase hyperproducer Morganella morganii clinical isolate (the M1 strain). Results were compared with those of the effect of salicylate in a wild-type M. morganii strain.
MarÃa M. TavÃo +6 more
openaire +1 more source
, 2021 A novel, facile, highly efficient and stereoselective protocol for the synthesis of cis-3-allyl-3-phenylsulfinyl-β-lactams and 3-allylidene-β-lactams from cis-3-allyl-3-phenylthio-β-lactams using Selectfluor both as an oxidizing agent and as an ...
Suvidha Pandey (11835468) +4 more
core +1 more source
Evaluation of Metallo-β-Lactamase Susceptibility Testing in a Physiologic Medium
Microbiology Spectrum, 2021 Research in identifying alternative growth media that better mimic host conditions is gaining ground. Relative to nutrient-rich Mueller-Hinton broth (MHB), data on the influence of physiologic or host-mimicking media on metallo-β-lactamase (MBL ...
Tomefa E. Asempa +4 more
doaj +1 more source
Cell Reports, 2019 Summary: Whereas the primary actions of β-lactams are well characterized, their downstream effects are less well understood. Although their targets are extracellular, β-lactams stimulate respiration in Escherichia coli leading to increased intracellular ...
Loïc Léger +5 more
doaj +1 more source
Conversion of Glucuronic Acid Glycosides to Novel Bicyclic β-Lactams
, 2016 Methodology for the conversion of glucuronic acid glycosides to novel bicyclic β-lactams is reported. Using this strategy, we prepared two novel templates suitable for use in combinatorial chemistry strategies for the construction of a number of ...
Timothy B. Durham (1698085) +1 more
core +2 more sources
β-Lactam induction of colanic acid gene expression inEscherichia coli [PDF]
FEMS Microbiology Letters, 2003 An unexpected observation led us to examine the relationship between beta-lactam exposure and synthesis of colonic acid capsular polysaccharide in Escherichia coli. Strains containing a cps-lacZ transcriptional fusion were challenged with antibiotics having various modes of action, and gene expression was detected by a disk-diffusion assay and in broth
Frances C, Sailer +2 more
openaire +2 more sources