Results 21 to 30 of about 38,167 (247)

High Prevalence of blaOXA-2 and blaOXA-10 Genes in the β-Lactam-Resistant Clinical Isolates of Pseudomonas aeruginosa [PDF]

Research in Molecular Medicine, 2022
Background: Increased resistance to β-lactams is one of the most important considerations about Pseudomonas aeruginosa. This study aimed to investigate the prevalence of blaOXA-2 and blaOXA-10 genes in β-lactam-resistant P. aeruginosa.
Fatemeh Bazari Jamkhaneh, Mina Owrang, Hamid Reza Goli   +2 more
doaj  

Salicylate decreases production of AmpC type β-lactamases and increases susceptibility to β-lactams in aMorganella morganiiclinical isolate [PDF]

FEMS Microbiology Letters, 2004
The effect of salicylate, a marRAB inducer, on the resistance to β-lactams was characterized in an AmpC β-lactamase hyperproducer Morganella morganii clinical isolate (the M1 strain). Results were compared with those of the effect of salicylate in a wild-type M. morganii strain.
María M. Tavío, Mariagrazia Perilli, Jordi Vila, Pino Becerro, Lucía Casañas, Gianfranco Amicosante, María Teresa Jiménez de Anta   +6 more
openaire   +1 more source

Penicillin‐binding protein PBP2a provides variable levels of protection toward different β‐lactams in Staphylococcus aureus RN4220

MicrobiologyOpen, 2020
Methicillin‐resistant Staphylococcus aureus (MRSA) is resistant to most β‐lactams due to the expression of an extra penicillin‐binding protein, PBP2a, with low β‐lactam affinity.
Marte Ekeland Fergestad, Gro Anita Stamsås, Danae Morales Angeles, Zhian Salehian, Yngvild Wasteson, Morten Kjos   +5 more
doaj   +1 more source

Evaluation of Metallo-β-Lactamase Susceptibility Testing in a Physiologic Medium

Microbiology Spectrum, 2021
Research in identifying alternative growth media that better mimic host conditions is gaining ground. Relative to nutrient-rich Mueller-Hinton broth (MHB), data on the influence of physiologic or host-mimicking media on metallo-β-lactamase (MBL ...
Tomefa E. Asempa, Hannah Bajor, Jessica H. Mullins, Janice Hartnett, David P. Nicolau   +4 more
doaj   +1 more source

β-Lactam Exposure Triggers Reactive Oxygen Species Formation in Enterococcus faecalis via the Respiratory Chain Component DMK

Cell Reports, 2019
Summary: Whereas the primary actions of β-lactams are well characterized, their downstream effects are less well understood. Although their targets are extracellular, β-lactams stimulate respiration in Escherichia coli leading to increased intracellular ...
Loïc Léger, Aurélie Budin-Verneuil, Margherita Cacaci, Abdellah Benachour, Axel Hartke, Nicolas Verneuil   +5 more
doaj   +1 more source

Microwave-induced Conversion of Electromagnetic Energy into Heat Energy in Different Solvents: Synthesis of β-lactams

Chemistry Journal of Moldova: General, Industrial and Ecological Chemistry, 2021
In this work, the stereospecific synthesis of optically active cis β-lactams under diverse microwave-induced conditions using diverse solvents was reported.
Aparna Das, Ram Naresh Yadav, Bimal Krishna Banik   +2 more
doaj   +1 more source

β-Lactam induction of colanic acid gene expression inEscherichia coli [PDF]

FEMS Microbiology Letters, 2003
An unexpected observation led us to examine the relationship between beta-lactam exposure and synthesis of colonic acid capsular polysaccharide in Escherichia coli. Strains containing a cps-lacZ transcriptional fusion were challenged with antibiotics having various modes of action, and gene expression was detected by a disk-diffusion assay and in broth
Frances C, Sailer, Bernadette M, Meberg, Kevin D, Young   +2 more
openaire   +2 more sources

Involvement of O8-antigen in altering β-lactam antibiotic susceptibilities inEscherichia coli [PDF]

FEMS Microbiology Letters, 2008
In spite of being dispensable, O-antigens are believed to facilitate various cellular processes and alter antibiotic sensitivities. Escherichia coli K-12 (CS109) strains are lacking in O-antigens and are reported to be sensitive to antibiotics. To our surprise, E. coli 2443 (expressing O8-antigen) manifested two- to fourfold higher sensitivities toward
Sujoy K, Sarkar, Anindya S, Ghosh
openaire   +2 more sources

Historical Review of the Penicillin and Related Compounds (β – Lactams)

Al-Mustansiriyah Journal of Pharmaceutical Sciences, 2018
In spite of  the old age of beta lactam, they continue to provide good health and preventing human diseases by virtue of  industrial production and discoveries of small new beta-lactam group of secondary metabolite.
Luma Salman Abd
doaj   +1 more source

Detection of an IS21 insertion sequence in the mexR gene of Pseudomonas aeruginosa increasing β-lactam resistance [PDF]

FEMS Microbiology Letters, 2004
To understand the regulation of the MexAB OprM efflux system in a clinical strain of Pseudomonas aeruginosa presenting a decreased susceptibility to ticarcillin and aztreonam, the mexR repressor gene was amplified by polymerase chain reaction (PCR) and was shown to be disrupted by an insertion sequence of more than 2 kb, with characteristic direct and ...
Boutoille, David, Corvec, Stéphane, Caroff, Nathalie, Giraudeau, Cécile, Espaze, Eric, Caillon, Jocelyne, Plesiat, Patrick, Reynaud, Alain   +7 more
openaire   +2 more sources