Results 101 to 110 of about 900,428 (178)

Supplemental_Material_for_NMNAT_Screening_Assay__by_Haubrich_et_al – Supplemental material for Development of a Bioluminescent High-Throughput Screening Assay for Nicotinamide Mononucleotide Adenylyltransferase (NMNAT)

, 2019
Supplemental material, Supplemental_Material_for_NMNAT_Screening_Assay__by_Haubrich_et_al for Development of a Bioluminescent High-Throughput Screening Assay for Nicotinamide Mononucleotide Adenylyltransferase (NMNAT) by Brad A.
Brad A. Haubrich (7467089), Chakk Ramesha (2551129), David C. Swinney (793616)   +2 more
core   +1 more source

Highly Bioadaptable Hybrid Conduits with Spatially Bidirectional Structure for Precision Nerve Fiber Regeneration via Gene Therapy

Advanced Science
Peripheral nerve deficits give rise to motor and sensory impairments within the limb. The clinical restoration of extensive segmental nerve defects through autologous nerve transplantation often encounters challenges such as axonal mismatch and ...
Renliang Zhao, Xiangtian Deng, Jizhao Dong, Chen Liang, Xiaozhong Yang, Yunfeng Tang, Juan Du, Zilu Ge, Dong Wang, Yifan Shen, Lianghua Jiang, Wei Lin, Tonghe Zhu, Guanglin Wang   +13 more
doaj   +1 more source

NMN/NAD+/SIRT1 axis activates NAMPT to ameliorate H2O2-triggered the impairment of progesterone synthesis in ovarian granulosa cells

Journal of Ovarian Research
Oxidative stress is a major driver of granulosa cell (GC) dysfunction and disrupted steroidogenesis. However, the mechanisms underlying oxidative stress–induced progesterone synthesis impairment and potential intervention strategies remain inadequately ...
Yunduan Wang, Qiao Li, Yueyue Li, Zifeng Ma, Hongmei Xu, Kechao Chen, Jian Li, Daoliang Lan, Wei Fu   +8 more
doaj   +1 more source

CD38 mediates nicotinamide mononucleotide base exchange to yield nicotinic acid mononucleotide

Nicotinamide mononucleotide (NMN) is a widely investigated metabolic precursor to the prominent enzyme cofactor NAD+, where it is assumed that delivery of this compound results in its direct incorporation into NAD+ via the canonical salvage/recycling ...
Wu, LE ; https://orcid.org/, Turner, N ; https://orcid.org/, Madawala, R, Hancock, SE ; https://orcid.org/, Quek, LE, Banks, JL   +5 more
core   +1 more source

Determination of β-nicotinamide mononucleotide content in eggs by high-performance liquid chromatography

Siliao yanjiu
This study aimed to establish a high-performance liquid chromatography method for the determination of β-nicotinamide mononucleotide (NMN) content in eggs. The chromatographic conditions were as follows: A Shimadzu Inert Sustain AQ-C18 column (4.6 mm×250.
LI Songhan, XU Jianyue, YE Xiaoqian, YU Xiaoxue, REN Chaoqi, ZHAO Xin, LI Liuan   +6 more
doaj  

Therapeutic effects of combined administration of β-nicotinamide mononucleotide and taurine on experimental silicosis in rats

Zhiye weisheng yu yingji jiuyuan
Objective To investigate the therapeutic effects of β-nicotinamide mononucleotide(β-NMN) and taurine, administered in combination, on experimental silicosis in rats.
GAN Yongjin
doaj   +1 more source

Nicotinamide Mononucleotide Supplementation Alleviates Doxorubicin-Induced Multi-Organ Fibrosis

Doxorubicin (DOX) is a potent chemotherapeutic agent known for its multi-organ toxicity, especially in the heart, which limits its clinical application. The toxic side effects of DOX, including DNA damage, oxidative stress, mitochondrial dysfunction and ...
Zhiliang Xi, Yuanlong Ge, Shenglong Yang, Wenjing Wei, Anhua Xu, Zhenyu Ju, Fei Wen, Shu Wu   +7 more
core   +1 more source

Identification and functional evaluation of Leishmania braziliensis Nicotinamide Mononucleotide Adenylyltransferase

, 2015
The progressive increase in Leishmania resistance to current control approaches prompts the need to develop therapeutic strategies based on comprehensive knowledge of the parasite’s biology.
Contreras, L., Ramírez, M., Neme, R.
core   +1 more source

Neuronal C/EBPβ Shortens the Lifespan via Inactivating NAMPT

Advanced Science
The brain plays a central role in aging and longevity in diverse model organisms. Morphological and functional alteration in the aging brain elicits age‐associated neuronal dysfunctions. However, the primary mechanism deteriorating the brain functions to
Bowei Li, Zhongyun Xie, Mengmeng Wang, Shuke Nie, Zhengjiang Qian, Xin Meng, Xia Liu, Seong Su Kang, Keqiang Ye   +8 more
doaj   +1 more source

Decrease of NAD+ Inhibits the Apoptosis of OLP T Cells via Inducing Mitochondrial Fission

Journal of Inflammation Research
Zhuo-Yu Zhang,1 Fang Wang,1,2 Gang Zhou1,3 1State Key Laboratory of Oral & Maxillofacial Reconstruction and Regeneration, Key Laboratory of Oral Biomedicine Ministry of Education, Hubei Key Laboratory of Stomatology, School & Hospital of Stomatology ...
Zhang ZY, Wang F, Zhou G
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