Results 91 to 100 of about 900,428 (178)

Therapeutic Effect of Nicotinamide Mononucleotide for Hypoxic–Ischemic Brain Injury in Neonatal Mice

, 2023
A clinical challenge remains in the treatment of hypoxic–ischemic brain injury in newborns. Nicotinamide adenine dinucleotide (NAD + ) has beneficial effects in animal models of adult stroke.
Tetyana Chumak, Carina Mallard, Hagberg, Henrik,, Seyedeh Marziyeh Jabbari Shiadeh, Chumak, Tetyana,, Singh-Mallah, Gagandeep,, Sandberg, Mats,, Ikeda, T., Kawamura, Takuya,, Svedin, Pernilla,, Gagandeep Singh Mallah, Maryam Ardalan, Fanny Goretta, Tomoaki Ikeda, Goretta, Fanny,, Mallard, Carina,, Mats Sandberg, Pernilla Svedin, Henrik Hagberg, Ardalan, Maryam,, Jabbari Shiadeh, Seyedeh Marziyeh,, Takuya Kawamura, Lina Jonsson, Jonsson, Lina   +23 more
core   +1 more source

Structural insights into Plasmodium falciparum nicotinamide mononucleotide adenylyltransferase: oligomeric assembly

, 2018
The biochemical pathways involved in nicotinamide adenine dinucleotide (NAD) biosynthesis converge at the enzymatic step catalysed by nicotinamide mononucleotide adenylyltransferase (NMNAT, EC: 2.7.7.1).
María Helena Ramírez-Hernández (5500646), Luis Ernesto Contreras-Rodríguez (5500655), Catherin Yizet Marin-Mogollon (5500652), Catherin Yizet Marin-Mogollon, Luis Ernesto Contreras-Rodríguez, María Helena Ramírez-Hernández, Lina Marcela Sánchez-Mejía (5500649), Lina Marcela Sánchez-Mejía   +7 more
core   +1 more source

Structure and function of nicotinamide mononucleotide adenylyltransferase

, 2004
The enzyme nicotinamide mononucleotide adenylyltransferase (NMNAT), a member of the nucleotidyltransferase alpha/beta phosphodiesterase superfamily, catalyzes the reaction NMN + ATP = NAD + PPi, representing the final step in the biosynthesis of NAD, a ...
AMICI, Adolfo, MAGNI, GIULIO, ORSOMANDO, Giuseppe, EMANUELLI, Monica, RUGGIERI, Silverio, RAFFAELLI, Nadia   +5 more
core   +1 more source

β-nicotinamide mononucleotide production in Vibrio natriegens: a preliminary study

bioRxiv
Background Nicotinamide mononucleotide (NMN), is a promising nutraceutical attracting much attention for its pharmacological and anti-aging efficacies.
L. Tran, Vu Thao Phuong Tran, H. Pham, Giang Nguyen, Tuoi Thi Nghiem, A. Pham, Nga Quynh Pham, Thuy Thi Le, Ngoc Lan Nguyen, Dang Nhat Minh Tran, T. Trần, Van Khanh Tran, H. Le   +12 more
semanticscholar   +1 more source

β-Nicotinamide Mononucleotide Prevents Senescence and Lipid Accumulation in Hepatic Stellate Cells by Restoring SIRT1 Function.

Chemico-Biological Interactions
The activation of hepatic stellate cells (HSCs) plays a vital role in liver wound healing, including liver regeneration and repair. However, as senescent cells increase with the continued activation, the secretion of extracellular matrix, collagen ...
Tomofumi Saka, Riri Hayashi, Yuta Yoshino, Taichi Mitsui, Hiroe Maruyama, Hiroyuki Kono, Mitsuyasu Kawaguchi, H. Nakagawa, Akira Ikari, Satoshi Endo   +9 more
semanticscholar   +1 more source

Identification of the nicotinamide mononucleotide adenylyltransferase of Trypanosoma cruzi [PDF]

, 2015
The intracellular parasite Trypanosomacruzi is the aetiological agent of Chagas disease, a public health concern with an increasing incidence rate. This increase is due, among other reasons, to the parasite’s drug resistance mechanisms, which require ...
Katherine Figarella, Nicolás Forero-Baena, Luis E Contreras, María H Ramírez, Carlos H Niño, Diana Sánchez-Lancheros   +5 more
core   +1 more source

Nicotinamide Mononucleotide From Bacillus licheniformis MW301654 Unravels the Nematicidal Property Against Meloidogyne incognita

Ashraf S, Nayana RUK, Nakkeeran S, et al. Nicotinamide Mononucleotide From <i>Bacillus licheniformis</i> MW301654 Unravels the Nematicidal Property Against <i>Meloidogyne incognita</i>. Journal of Basic Microbiology.
Nayana, R. U. Krishna, Fatimah, Nusrat, Raish, Mohammad, Ashraf, Suhail, Nallusamy, Saranya, Jardan, Yousef A. Bin, Nakkeeran, Sevugapperumal   +6 more
core   +1 more source

Slc12a8 is a nicotinamide mononucleotide transporter

, 2019
Nicotinamide mononucleotide (NMN) is a biosynthetic precursor of NAD+ known to promote cellular NAD+ production and counteract age-associated pathologies associated with a decline in tissue NAD+ levels.
Mills, Kathryn F, Sasaki, Yo, Lei, Hanyue Cecilia, Yoshino, Jun, Tokizane, Kyohei, Imai, Shin-Ichiro, Sociali, Giovanna, Grozio, Alessia, Bruzzone, Santina, Migaud, Marie E, Cunningham, Richard   +10 more
core   +1 more source

Spatial regulation of NMN supplementation on brain lipid metabolism upon subacute and sub-chronic PM exposure in C57BL/6 mice

Particle and Fibre Toxicology
Background Atmospheric particulate matter (PM) exposure-induced neuroinflammation is critical in mediating nervous system impairment. However, effective intervention is yet to be developed.
Yue Jiang, Fang Li, Lizhu Ye, Rui Zhang, Shen Chen, Hui Peng, Haiyan Zhang, Daochuan Li, Liping Chen, Xiaowen Zeng, Guanghui Dong, Wei Xu, Chunyang Liao, Rong Zhang, Qian Luo, Wen Chen   +15 more
doaj   +1 more source

Exogenous nicotinamide mononucleotide, NAMPT-catalyzed reaction end product, reverts the inhibitory effects of APO866.

, 2013
Mouse PEC were incubated in the presence or absence of 200 nM APO866 and 10 mM nicotinamide mononucleotide (NMN). Cells were further stimulated with LPS and intracellular NAD levels and TNFα and IL-6 secretion were determined.
Frédéric Van Gool (198333), Thibaut De Smedt (76288), Massimo Nobile (377676), Nathalie Busso (8780), Alexander So (8781), Mahir Karababa (377675), Oberdan Leo (33376), Mara Galli (377678), Aline Rolaz (377677)   +8 more
core   +1 more source