Results 71 to 80 of about 31,357 (216)
Genome MedicineBackground γδ T cells represent a heterogeneous family of innate-like lymphocytes with adaptive immunity features. Although abundant in barrier tissues such as skin and intestine, γδ T cells are rare in the cardiovascular system, which severely limits ...
Zhihua Wang +20 more
doaj +1 more source
MicroRNA-181a/b-1 Is Not Required for Innate γδ NKT Effector Cell Development.
PLoS ONE, 2015 Thymic development of αβ T lymphocytes into invariant natural killer (NK) T cells depends on their selection via agonistic lipid antigen presented by CD1d. If successful, newly selected NKT cells gain effector functions already in the thymus.
Inga Sandrock +6 more
doaj +1 more source
Advanced Science, EarlyView.HfO2‐based ferroelectrics exhibit wake‐up and fatigue behaviors during electrical cycling, significantly affecting device endurance and reliability. These phenomena are governed by defect dynamics, including oxygen vacancy redistribution and charge trapping.
Hongseok Kim +6 more
wiley +1 more source
Revealing the Giant Electromechanical Effects in Yttria‐Stabilized Zirconia Single Crystal
Advanced Science, EarlyView.Giant electromechanical responses are uncovered in yttria‐stabilized zirconia single crystal (SC‐YSZ), exhibiting pronounced orientation dependence. The giant electrostriction and piezoelectricity are directly correlated with the long‐range transport kinetics of oxygen vacancies.
Zhuwu Yi +8 more
wiley +1 more source
Advanced Science, EarlyView.Embryonic amoxicillin exposure disrupts multi‐organ development in zebrafish larvae through a lncRNA–metabolic enzyme regulatory axis. PCALRx associates with pyruvate carboxylase, promotes PC protein ubiquitination, and impairs mitochondrial energy metabolism, while vitamin B1 partially restores PC‐centered metabolic function and developmental outcomes.
Yixue Yao +5 more
wiley +1 more source
Advanced Science, EarlyView.Exposure to CS causes an elevation of AARS1 levels, which increases the levels of RUNX3 lactylation at the K193 site and increases protein levels of RUNX3 through inhibition of autolysosomal degradation. Elevated RUNX3 levels promote CD8+T cell activation and augment their cytotoxicity, which induces alveolar epithelial cell death and facilitates the ...
Ying Zhu +12 more
wiley +1 more source
Advanced Science, EarlyView.Organosilicon micelles enable background‐free molecular magnetic resonance imaging (MRI) while remaining fully compatible with standard proton (1H) hardware. By exploiting a spectrally silent 1H window at ∼0 ppm, the silicone nanotracer allows hotspot detection by 1H chemical‐shift imaging (CSI) without metals or heteronuclei, enabling direct overlay ...
Martin Orsagh +4 more
wiley +1 more source
Performance Estimation and Ex Vivo Validation of Untethered Magnetic Robots in Soft Tissue
Advanced Science, EarlyView.This study presents an empirical model that quantitatively predicts the step‐out frequency of screw‐type untethered magnetic robots (UMRs) in soft viscoelastic environments, including ex vivo brain tissue. By integrating key parameters into a dimensionless framework, the model enables estimation of robot performance across a range of biological ...
Leendert‐Jan W. Ligtenberg +19 more
wiley +1 more source
Advanced Science, EarlyView.A Sr‐free air electrode for high‐temperature solid oxide cells is designed by independently tailoring electronic conduction, ionic transport, and surface catalysis using complementary Sr‐free phases and infiltrated nanocatalysts. It delivers performance comparable to state‐of‐the‐art Sr‐containing electrodes while completely suppressing Cr‐induced ...
Ji‐eun Won +10 more
wiley +1 more source
m6A‐Driven Pexophagy Triggers Placental Ferroptosis to Impair Fetal Growth Upon Environmental Stress
Advanced Science, EarlyView.Prenatal environmental stress exposure promotes m6A modification to drive PEX2‐dependent pexophagy, thereby causing placental ferroptosis and FGR. ABSTRACT The role and underlying mechanisms of placental ferroptosis in fetal growth restriction (FGR) induced by environmental stress remain poorly understood.
Xin‐Xin Zhang +18 more
wiley +1 more source