Results 131 to 140 of about 29,069 (201)

Structure and dynamics of γ-secretase with presenilin 2 compared to presenilin 1

, 2019
Budheswar Dehury, Ning Tang, Tom L. Blundell, Kasper P. Kepp   +3 more
openalex   +2 more sources

β- and γ-Secretases and Lipid Rafts [PDF]

, 2010
Wataru Araki
openalex   +1 more source

The causative role of amyloidosis in the cardiac complications of Alzheimer's disease: a comprehensive systematic review

The Journal of Physiology, Volume 604, Issue 4, Page 1646-1681, 15 February 2026.
Abstract figure legend Schematic illustration of the bidirectional causative link between cerebral amyloid‐beta (Aβ) angiopathy and cardiovascular disease in Alzheimer's disease (AD). Common cardiovascular risk factors like microvascular thrombosis, diabetes, atrial fibrillation, hypertension and atherosclerosis lead to cerebral hypoperfusion and ...
Samuel Parker, Andrew F. James, Svetlana Mastitskaya   +2 more
wiley   +1 more source

Bacteroides fragilis toxin stimulates intestinal epithelial cell shedding and γ-secretase-dependent E-cadherin cleavage

, 2007
Shaoguang Wu, Ki‐Jong Rhee, Ming Zhang, Augusto A. Franco, Cynthia L. Sears   +4 more
openalex   +2 more sources

The innate immunity protein IFITM3 modulates γ-secretase in Alzheimer’s disease

, 2020
Ji‐Yeun Hur, Georgia Frost, Xianzhong Wu, Christina J. Crump, Si Pan, Eitan Wong, Marilia Barros, Thomas Li, Pengju Nie, Yujia Zhai, Jen Chyong Wang, Julia TCW, Lei Guo, Andrew McKenzie, Ming Chen, Xianxiao Zhou, Minghui Wang, Yotam Sagi, Alan E. Renton, Bianca Esposito, Yong Kim, Katherine R. Sadleir, Ivy Trinh, Robert A. Rissman, Robert Vassar, Bin Zhang, Douglas S. Johnson, Eliezer Masliah, Paul Greengard, Alison Goate, Yue‐Ming Li   +30 more
openalex   +2 more sources

Correction: Monoubiquitination and endocytosis direct γ-secretase cleavage of activated Notch receptor [PDF]

, 2004
Neetu Gupta, Emmanuelle Six, Odile LeBail, Frédérique Logeat, Patricia Chastagner, Annie Olry, Alain Israël, Christel Brou   +7 more
openalex   +1 more source

Discovery of a Potent Pyrazolopyridine Series of γ-Secretase Modulators

, 2011
Jun Qin, Wei Zhou, Xianhai Huang, Pawan Dhondi, Anandan Palani, Robert Aslanian, Zhaoning Zhu, William J. Greenlee, Mary Cohen-Williams, Nicholas A. Jones, Lynn A. Hyde, Lili Zhang   +11 more
openalex   +1 more source

The role of γ-secretase in familial hidradenitis suppurativa: Implications for pathogenesis and targeted therapy. [PDF]

JAAD Case Rep
Desta B, Korytnikova E, Tessier-Kay M, Klufas T, Lu J, Sarfo A, Zhou AE.   +6 more
europepmc   +1 more source

Interaction of Substrates with γ-Secretase at the Level of Individual Transmembrane Helices-A Methodological Approach. [PDF]

Int J Mol Sci, 2023
Pauli TM, Julius A, Costa F, Eschrig S, Moosmüller J, Fischer L, Schanzenbach C, Schmidt FC, Ortner M, Langosch D.   +9 more
europepmc   +1 more source

Nicastrin Is Dispensable for γ-Secretase Protease Activity in the Presence of Specific Presenilin Mutations [PDF]

, 2009
Eugene Futai, Sosuke Yagishita, Shoichi Ishiura   +2 more
openalex   +1 more source