Results 141 to 150 of about 40,728 (191)

Neutrophil extracellular traps activate Notch-γ-secretase signaling in hidradenitis suppurativa. [PDF]

J Allergy Clin Immunol
Oliveira CB, Romo-Tena J, Patino-Martinez E, Woo A, Byrd AS, Kim D, Okoye GA, Kaplan MJ, Carmona-Rivera C.   +8 more
europepmc   +1 more source

Hepcidin expression is associated with increased γ-secretase-mediated cleavage of neogenin in the liver. [PDF]

J Biol Chem
Enns CA, Zhang RH, Jue S, Zhang AS.
europepmc   +1 more source

Daurisoline Inhibits Progression of Triple-Negative Breast Cancer by Regulating the γ-Secretase/Notch Axis. [PDF]

Biomol Ther (Seoul)
Zhan X, Chen X, Feng M, Yao K, Yang K, Jia H.   +5 more
europepmc   +1 more source

Selective Protonation of Catalytic Dyad for γ-Secretase-Mediated Hydrolysis Revealed by Multiscale Simulations. [PDF]

J Phys Chem B
Wu B, Li S, Han W.
europepmc   +1 more source

Correction: γ‑Secretase modulator resistance of an aggressive Alzheimer‑causing presenilin mutant can be overcome in the heterozygous patient state by a set of advanced compounds. [PDF]

Alzheimers Res Ther
Trambauer J, Sarmiento RMR, Garringer HJ, Salbaum K, Pedro LD, Crusius D, Vidal R, Ghetti B, Paquet D, Baumann K, Lindemann L, Steiner H.   +11 more
europepmc   +1 more source

Spectrum of γ-Secretase dysfunction as a unifying predictor of ADAD age at onset across PSEN1, PSEN2 and APP causal genes. [PDF]

Mol Neurodegener
Fernández SG, Oria CG, Petit D, Annaert W, Ringman JM, Fox NC, Ryan NS, Chávez-Gutiérrez L.   +7 more
europepmc   +1 more source

γ-secretase facilitates retromer-mediated retrograde transport.

J Cell Sci
Takeo Y, Crite M, Mehmood K, DiMaio D.
europepmc   +1 more source

γ-Secretase: once and future drug target for Alzheimer's disease. [PDF]

Expert Opin Drug Discov
Wolfe MS.
europepmc   +1 more source

Familial Alzheimer mutations stabilize synaptotoxic γ-secretase-substrate complexes. [PDF]

Cell Rep
Devkota S, Zhou R, Nagarajan V, Maesako M, Do H, Noorani A, Overmeyer C, Bhattarai S, Douglas JT, Saraf A, Miao Y, Ackley BD, Shi Y, Wolfe MS.   +13 more
europepmc   +1 more source