Results 151 to 160 of about 29,069 (201)

Shedding and γ-secretase-mediated intramembrane proteolysis of the mucin-type molecule CD43 [PDF]

, 2005
Christian X. Andersson, Julia Fernández-Rodrı́guez, Sirle Laos, Dan Baeckström, Christian Haass, Gunnar C. Hansson   +5 more
openalex   +1 more source

Presenilin Loss Impairs Synaptic Transmission and Causes Axonal Degeneration through Ryanodine Receptor Dysfunction, Independent of γ-Secretase Activity. [PDF]

J Neurosci
Du X, Niu L, Ragan M, Fracz Z, Wang ZW.
europepmc   +1 more source

Membrane lipid remodeling modulates γ-secretase processivity. [PDF]

J Biol Chem, 2023
Dawkins E, Derks RJE, Schifferer M, Trambauer J, Winkler E, Simons M, Paquet D, Giera M, Kamp F, Steiner H.   +9 more
europepmc   +1 more source

γ-secretase facilitates retromer-mediated retrograde transport. [PDF]

J Cell Sci
Takeo Y, Crite M, Mehmood K, DiMaio D.
europepmc   +1 more source

Leptin regulates amyloid β production via the γ-secretase complex

, 2012
Dana M. Niedowicz, Christa M. Studzinski, Adam M. Weidner, Thomas L Platt, Kristen N. Kingry, Tina L. Beckett, Annadora J. Bruce‐Keller, Jeffrey N. Keller, M. Paul Murphy   +8 more
openalex   +2 more sources

Structural Modeling of γ -Secretase A β _n Complex Formation and Substrate Processing [PDF]

, 2018
Manuel Hitzenberger, Martin Zacharias
openalex   +1 more source

The human RAP1 and GFAPɛ proteins increase γ-secretase activity in a yeast model system. [PDF]

G3 (Bethesda), 2023
Swanson MJ, Lewis KN, Carpenter R, Whetzel A, Bae NS.   +4 more
europepmc   +1 more source

Design, synthesis, and structure–activity relationship studies of N-arylsulfonyl morpholines as γ-secretase inhibitors

, 2010
Hongmei Li, Ruo Xu, David Cole, John W. Clader, William J. Greenlee, Amin A. Nomeir, Lixin Song, Lili Zhang   +7 more
openalex   +1 more source

γ‐Secretase cleavage of the Alzheimer risk factor TREM 2 is determined by its intrinsic structural dynamics

, 2020
Andrea K. Steiner, Kai Schlepckow, Bettina Brunner, Harald Steiner, Christian Haass, Franz Hagn   +5 more
openalex   +1 more source

Presenilin-1 Familial Alzheimer Mutations Impair γ-Secretase Cleavage of APP Through Stabilized Enzyme-Substrate Complex Formation. [PDF]

Biomolecules
Devkota S, Maesako M, Wolfe MS.
europepmc   +1 more source