Results 81 to 90 of about 322,712 (165)

Palm oil γ-tocotrienol and α-tocopherol act as potent inducers in the immune response of mouse splenocytes in vitro / Narimah Abdul Hamid Hasani, Khalid bin Abdul Kadir and Wan Zurinah Wan Ngah [PDF]

, 2011
Vitamin E may have anti carcinogenesis effect in human and animal models via the mechanism of cell cycle arrest and enhancement of immune system. The cell-mediated immune inducing properties of palm oil vitamin E, for example, γ-tocotrienol and α ...
Abdul Kadir, Khalid, Wan Ngah, Wan Zurinah, Abdul Hamid Hasani, Narimah   +2 more
core  

Abstract 5417: Suppression in mevalonate synthesis mediates the antiproliferative effects of combined statin and γ-tocotrienol treatment in mammary tumor cells

, 2010
Statins directly inhibit 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGR) activity, while γ-tocotrienol, an isoform of vitamin E, enhances the degradation and reduces the cellular levels of HMGR in various tumor cell lines.
Vikram B. Wali, Paul W. Sylvester, Sunitha V. Bachawal   +2 more
core   +1 more source

The Protective Effects of γ-Tocotrienol on Muscle Stem Cells Through Inhibiting Reactive Oxidative Stress Production. [PDF]

Front Cell Dev Biol, 2022
Yang S, Yang J, Zhao H, Deng R, Fan H, Zhang J, Yang Z, Zeng H, Kuang B, Shao L.   +9 more
europepmc   +1 more source

γ‑tocotrienol prevents 5‑FU‑induced reactive oxygen species production in human oral keratinocytes through the stabilization of 5‑FU‑induced activation of Nrf2 [PDF]

, 2015
Chemotherapy‑induced oral mucositis is a common adverse event in patients with oral squamous cell carcinoma, and is initiated through a variety of mechanisms, including the generation of reactive oxygen species (ROS).
Takano, Hideyuki, 山村, 佳子, 60427/profile-ja.html, Azuma, Masayuki, 221816/profile-ja.html, モモタ, ユキヒロ, 00581406, 可児, 耕一, 1711, 60389/profile-ja.html, 青田, 桂子, 634, ヤマノイ, トモコ, 20144983, 261577/profile-ja.html, Yamanoi, Tomoko, カニ, コウイチ, ヤマムラ, ヨシコ, 山ノ井, 朋子, 高野, 栄之, アオタ, ケイコ, 東, 雅之, 30380091, タカノ, ヒデユキ, Yamamura, Yoshiko, アズマ, マサユキ, 1690, 60709583, 486, 487, 685, 桃田, 幸弘, 00304543, Momota, Yukihiro, 70437391, Kani, Kohichi, Aota, Keiko   +36 more
core  

Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model. [PDF]

Life Sci Space Res (Amst), 2021
Nemec-Bakk AS, Sridharan V, Landes RD, Singh P, Cao M, Seawright JW, Liu X, Zheng G, Dominic P, Pathak R, Boerma M.   +10 more
europepmc   +1 more source

γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: Potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent

, 2011
BACKGROUND AND PURPOSE Activation of signal transducer and activator of transcription 3 (STAT3) play a critical role in the survival, proliferation, angiogenesis and chemoresistance of tumour cells.
Alan Prem Kumar (9505153), P. Rajendran (14150541), M. Shanmugam (752335), K. Manu (23321821), S. Loo (23323873), F. Li (1346211), G. Sethi (23308666)   +6 more
core  

γ-Tocotrienol Protects against Mitochondrial Dysfunction, Energy Deficits, Morphological Damage, and Decreases in Renal Functions after Renal Ischemia. [PDF]

Int J Mol Sci, 2021
Nowak G, Megyesi J.
europepmc   +1 more source

β-Tocotrienol Decreases PDGF-BB-Induced Proliferation and Migration of Human Airway Smooth Muscle Cells by Inhibiting RhoA and Reducing ROS Production

Pharmaceuticals
Background: Tocotrienols exhibit antioxidant and anti-inflammatory activities. RhoA, a small GTPase protein, plays a crucial role in regulating contractility in airway smooth muscle (ASM). Previous studies have demonstrated that γ-tocotrienols reduce ASM
Aditya Sri Listyoko, Ryota Okazaki, Tomoya Harada, Miki Takata, Masato Morita, Hiroki Ishikawa, Yoshihiro Funaki, Akira Yamasaki   +7 more
doaj   +1 more source

Genome-Wide Association and Genomic Prediction Models of Tocochromanols in Fresh Sweet Corn Kernels

The Plant Genome, 2019
Sweet corn ( L.), a highly consumed fresh vegetable in the United States, varies for tocochromanol (tocopherol and tocotrienol) levels but makes only a limited contribution to daily intake of vitamin E and antioxidants.
Matheus Baseggio, Matthew Murray, Maria Magallanes-Lundback, Nicholas Kaczmar, James Chamness, Edward S. Buckler, Margaret E. Smith, Dean DellaPenna, William F. Tracy, Michael A. Gore   +9 more
doaj   +1 more source

γ-Tocotrienol-Loaded Liposomes for Radioprotection from Hematopoietic Side Effects Caused by Radiotherapeutic Drugs. [PDF]

J Nucl Med, 2021
Lee SG, Kalidindi TM, Lou H, Gangangari K, Punzalan B, Bitton A, Lee CJ, Vargas HA, Park S, Bodei L, Kharas MG, Singh VK, Kishore Pillarsetty NV, Larson SM.   +13 more
europepmc   +1 more source