Results 51 to 60 of about 201,244 (157)

Selection of Wheat Germ Drying Methods Using Multi‐Criteria Decision‐Making Techniques

Journal of Food Process Engineering, Volume 49, Issue 8, August 2026.
The parameters for the analysis of dried wheat germ were weighted using the MEREC method, with the most critical criterion being antioxidant capacity. The COBRA method was employed to evaluate a total of 15 alternatives. The most effective drying method for wheat germ was determined to be the combination of vacuum pre‐drying and microwave finish‐drying
Aliye Ayca Supciller, Engin Demiray, Burçin Çulluk   +2 more
wiley   +1 more source

p27^Kip1 is required for δ-tocotrienol-induced G₁ arrest.

, 2013
A, p27Kip1 siRNA attenuates δ-tocotrienol-mediated growth suppression in human MIAPaCa-2 pancreatic cancer cells. After transfection with p27Kip1 siRNA or with noncoding siRNA for 24 hours, MIAPaCa-2 cells were incubated with fresh medium containing ...
Kazim Husain (285140), Anying Zhang (170940), Mokenge P. Malafa (285152), Yanbin Dong (24525), Jose M. Pimiento (285141), Dung-Tsa Chen (285149), Domenico Coppola (53952), Rony Francois (285144), Jiandong Chen (220306), Said M. Sebti (251548), Pamela J. Hodul (285137), Warren J. Pledger (285146)   +11 more
core   +1 more source

A Facile Semisynthesis and Evaluation of Garcinoic Acid and Its Analogs for the Inhibition of Human DNA Polymerase β

Molecules, 2020
Garcinoic acid has been identified as an inhibitor of DNA polymerase β (pol β). However, no structure-activity relationship (SAR) studies of garcinoic acid as a pol β inhibitor have been conducted, in part due to the lack of an efficient synthetic method
Satheesh Gujarathi, Maroof Khan Zafar, Xingui Liu, Robert L. Eoff, Guangrong Zheng   +4 more
doaj   +1 more source

Genome-wide association studies reveal novel QTLs, QTL-by-environment interactions and their candidate genes for tocopherol content in soybean seed

Frontiers in Plant Science, 2022
Genome-wide association studies (GWAS) is an efficient method to detect quantitative trait locus (QTL), and has dissected many complex traits in soybean [Glycine max (L.) Merr.].
Kuanwei Yu, Huanran Miao, Hongliang Liu, Jinghang Zhou, Meinan Sui, Yuhang Zhan, Ning Xia, Xue Zhao, Yingpeng Han   +8 more
doaj   +1 more source

Reconfiguring biofortification strategies to transform food systems and address micronutrient deficiency of the 21st century

Journal of Integrative Plant Biology, Volume 68, Issue 8, Page 2511-2547, August 2026.
This review explores how to make staple foods and horticultural crops more nutritious, including how artificial intelligence‐based screening of gene banks helps deploy nutritionally rich germplasm into breeding. Genome editing can help develop crops richer in minerals, vitamins, and health‐promoting compounds, supporting healthier diets and more ...
Rhowell Jr. N. Tiozon, Alisdair R. Fernie, Nese Sreenivasulu   +2 more
wiley   +1 more source

Antioxidants in Plant‐Based Food Matrices: From Structure–Activity and Degradation Kinetics to Formulation Design

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 4, July 2026.
ABSTRACT Plant‐based antioxidants are widely incorporated into foods to retard oxidative deterioration and to deliver health‐related benefits. Yet, their in‐product and in vivo performance frequently diverges from predictions based on solution‐phase chemical assays, because matrix interactions, processing history, and host metabolism reshape both ...
Márcio Vargas‐Ramella, Carmen Silvia Favaro‐Trindade, Bárbara Miranda‐Vilela, Mariana Estefanuto‐Costa, Marina Franco‐Brito, Bibiana Alves dos Santos, Paulo Cezar Bastianello Campagnol   +6 more
wiley   +1 more source

Impact of delta-tocotrienol on human melanoma cell proliferation [PDF]

, 2010
The rate-limiting enzyme of the mevalonate pathway, 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase, provides essential intermediates for the prenylation or dolichylation of growth-related proteins including nuclear Ras, nuclear lamins, and ...
Fernandes, Nicolle Valerie
core   +4 more sources

Efficacy of Off-Label Therapy for Non-alcoholic Fatty Liver Disease in Improving Non-invasive and Invasive Biomarkers: A Systematic Review and Network Meta-Analysis of Randomized Controlled Trials

Frontiers in Medicine, 2022
ObjectiveTo evaluate the effects of vitamin E, pioglitazone, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists in patients with non-alcoholic fatty liver disease (NAFLD).DesignA network meta-analysis.
Qian Luo, Qian Luo, Ruojun Wei, Ruojun Wei, Yuzi Cai, Yuzi Cai, Qihan Zhao, Qihan Zhao, Yuning Liu, Yuning Liu, Wei Jing Liu, Wei Jing Liu   +11 more
doaj   +1 more source

Extrusion and Pancreatin Superdosing Modulate the Metabolic Impact of 20% Chlorella vulgaris Inclusion in Broiler Diets

Journal of Animal Physiology and Animal Nutrition, Volume 110, Issue 4, Page 506-522, July 2026.
ABSTRACT Microalgae such as Chlorella vulgaris are gaining attention as sustainable and nutritionally valuable feed ingredients, with the potential to partially replace soybean meal in broiler diets. However, dietary inclusion of 20% C. vulgaris has been attempted, but negatively affected growth performance due to limited digestibility.
Ana Rita Mendes, Cátia Falcão Martins, Maria Pinheiro Spínola, Daniela Filipa Pires Carvalho, Obete Madacussengua, Joana Inês Ferreira, Ana Maria Fontes, Rui Manuel Amaro Pinto, Miguel Pedro Mourato, Adam Davis, André Martinho de Almeida, Madalena Lordelo, José António Mestre Prates   +12 more
wiley   +1 more source

δ-Tocotrienol (DT3) regulation of p27^Kip1 protein expression at the transcription level.

, 2013
A, MIAPaca-2 cells were treated with δ-tocotrienol at a predetermined IC50 and then with cyclohexamide to block protein synthesis. p27Kip1 turnover rate was examined by Western blot.
Kazim Husain (285140), Anying Zhang (170940), Mokenge P. Malafa (285152), Yanbin Dong (24525), Jose M. Pimiento (285141), Dung-Tsa Chen (285149), Domenico Coppola (53952), Rony Francois (285144), Jiandong Chen (220306), Said M. Sebti (251548), Pamela J. Hodul (285137), Warren J. Pledger (285146)   +11 more
core   +1 more source