Individual differences in the neuropsychopathology of addiction. [PDF]
, 2017 Drug addiction or substance-use disorder is a chronically relapsing disorder that progresses through binge/intoxication, withdrawal/negative affect and preoccupation/anticipation stages.
George, Olivier, Koob, George F
core
κ-Opioid Receptor Activation Modifies Dopamine Uptake in the Nucleus Accumbens and Opposes the Effects of Cocaine [PDF]
, 2000 Alexis C. Thompson +5 more
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Modulation of the Neurotoxic Effects of Methamphetamine by the Selective κ‐Opioid Receptor Agonist U69593 [PDF]
, 2000 Eman El- Daly +3 more
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Understanding ligand binding, selectivity and functions on the G protein-coupled receptors: A molecular modeling approach [PDF]
, 2014 The assessment of target protein molecular structure provides a distinct advantage in the rational drug design process. The increasing number of available G protein-coupled receptor crystal structures has enabled utilization of a varied number of ...
Zaidi, Saheem
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The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology. [PDF]
Nat Commun, 2023 Wang YJ +15 more
europepmc +1 more source
Mitogenic Signaling via Endogenous κ‐Opioid Receptors in C6 Glioma Cells [PDF]
, 2000 Laura Bohn +2 more
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Author Correction: Amygdala dynorphin/κ opioid receptor system modulates depressive-like behavior in mice following chronic social defeat stress. [PDF]
Acta Pharmacol Sin, 2023 Zan GY +10 more
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κ-Opioid Receptor Agonists Modulate Visceral Nociception at a Novel, Peripheral Site of Action [PDF]
, 2000 S. K. Joshi +3 more
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Discovery of κ Opioid Receptor (KOR)-Selective d-Tetrapeptides with Improved In Vivo Antinociceptive Effect after Peripheral Administration. [PDF]
ACS Med Chem Lett, 2022 Stefanucci A +14 more
europepmc +1 more source