Differential Agonist Regulation of the Human κ‐Opioid Receptor [PDF]
Allan D. Blake+4 more
openalex +1 more source
Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application
Molecular hydrogen, delivered through inhalation, hydrogen‐rich water, or hydrogen solution injection, reduces oxidative stress, regulates immune responses, facilitates cell repair, and alleviates inflammatory bowel disease (IBD) and intestinal injury.
Jiayi Jin+7 more
wiley +1 more source
Characterization of δ, κ, and μ Human Opioid Receptors Overexpressed in Baculovirus-infected Insect Cells [PDF]
Dominique Massotte+5 more
openalex +1 more source
ABSTRACT Myofascial pain syndrome (MPS) is a chronic regional pain condition characterized by trigger points—hyperirritable spots within taut bands of muscle fibers that cause both localized and referred pain. The pathogenesis, diagnostic criteria, and classification of MPS are still under investigation, which complicates the development of ...
Jeremy P. Steen+2 more
wiley +1 more source
Expression of δ, κ and µ human opioid receptors in Escherichia coli and reconstitution of the high‐affinity state for agonist with heterotrimeric G proteins [PDF]
Laura Stanasila+3 more
openalex +1 more source
ABSTRACT Objective Patients with cancer have a high risk of suicide. However, evidence‐based preventive measures remain unclear. This study aimed to investigate suicide prevention strategies for hospitalized patients with cancer by analyzing nationwide patient safety reports using large language models.
Ken Kurisu+5 more
wiley +1 more source
The claustrum-prelimbic cortex circuit through dynorphin/κ-opioid receptor signaling underlies depression-like behaviors associated with social stress etiology. [PDF]
Wang YJ+15 more
europepmc +1 more source
Reversion of muscarinic autoreceptor agonist‐induced acetylcholine decrease and learning impairment by dynorphin A (1–13), an endogenous κ‐opioid receptor agonist [PDF]
Masayuki Hiramatsu+3 more
openalex +1 more source
This case report presents the first documented case of opioid‐induced neurotoxicity in clinical veterinary medicine, with two cases of myoclonus symptoms following the administration of opioids (butorphanol and remifentanil). It also outlines practical guidelines that emphasize the premedication with midazolam and the exclusion of opioids in dogs with ...
Changhoon Nam+2 more
wiley +1 more source
A Study of the Kratom Alkaloids and Their Binding to the μ-Opioid Receptor [PDF]
Kratom, a plant commonly found in southeast Asia, has traditionally been used for medicinal treatments. Recently, however, the popularity of the drug has significantly increased due to its euphoric effects, leading to it being used as an alternative to ...
Chamblee, Reba Elizabeth Ann
core +1 more source