Results 111 to 120 of about 31,247 (253)

Gi- and Gs-coupled GPCRs show different modes of G-protein binding. [PDF]

open access: yes, 2018
More than two decades ago, the activation mechanism for the membrane-bound photoreceptor and prototypical G protein-coupled receptor (GPCR) rhodopsin was uncovered.
Altenbach, Christian   +7 more
core   +1 more source

Cervical epidural catheter for administration of detomidine and morphine in a model of carpal synovitis in the horse

open access: yesVeterinary Surgery, EarlyView.
Abstract Objective To determine the analgesic effects of detomidine and morphine administered by cervical epidural catheter (CEC) on a model of thoracic limb pain. Study design Prospective, randomized, blinded crossover study. Animals Five adult horses.
Veronica L. Edwards   +3 more
wiley   +1 more source

Perioperative management of septic peritonitis in small animals: A review

open access: yesVeterinary Surgery, EarlyView.
Abstract Background Septic peritonitis (SP) is a complex, life‐threatening disease, driven by peritoneal inflammation and microbial contamination, requiring timely and dynamic perioperative management. Aims The aim of this review was to synthesize current knowledge on the perioperative management of SP in dogs and cats.
Shana K. O'Marra, Bonnie G. Campbell
wiley   +1 more source

Ingestion of amniotic fluid enhances the facilitative effect of VTA morphine on the onset of maternal behavior in virgin rats [PDF]

open access: yes, 2009
Previous research has shown that injection of morphine into the ventral tegmental area(VTA) facilitates the onset of maternal behavior in virgin female rats, and injection of the opioid antagonist naltrexone into the VTA disrupts the onset of maternal ...
Daigler, Lindsey B.   +4 more
core  

Haemodynamic Changes After Prophylactic Doses of Ephedrine, Phenylephrine, Norepinephrine Versus Placebo During Induction of General Anaesthesia: A Randomised Trial

open access: yesActa Anaesthesiologica Scandinavica, Volume 70, Issue 1, January 2026.
ABSTRACT Background Ephedrine, phenylephrine, and norepinephrine are commonly used to manage hypotension during the induction of anaesthesia. The objective of this study was to evaluate whether prophylactic administration of assumed equipotent doses of these vasopressors could maintain systolic arterial blood pressure (SAP) and heart rate (HR) within ...
Gunnar Helge Sjøen   +4 more
wiley   +1 more source

GRK Mediates μ-Opioid Receptor Plasma Membrane Reorganization

open access: yesFrontiers in Molecular Neuroscience, 2019
Differential regulation of the μ-opioid receptor (MOP) has been linked to the development of opioid tolerance and dependence which both limit the clinical use of opioid analgesics.
Arisbel B. Gondin   +8 more
doaj   +1 more source

Spinal interaction between μ and δ opioid receptors in naive and morphine-tolerant rats [PDF]

open access: hybrid, 2009
Pál Riba   +5 more
openalex   +1 more source

Electroacupuncture as a treatment for suspected trigeminal nerve‐mediated head‐shaking in 42 horses

open access: yesEquine Veterinary Education, Volume 37, Issue 12, Page 647-653, December 2025.
Summary Background Electroacupuncture (EA) has been used successfully as a treatment for trigeminal nerve‐mediated head‐shaking (TMHS) in a small case series, but results from a larger number of cases are lacking. Objectives To retrospectively investigate the effectiveness of EA as a treatment for horses with TMHS.
B. Dunkel   +5 more
wiley   +1 more source

Src‐dependent phosphorylation of μ‐opioid receptor at Tyr336modulates opiate withdrawal [PDF]

open access: gold, 2017
Lei Zhang   +8 more
openalex   +1 more source

Multimodal Breathing Control: Pontomedullary Mechanisms and Current Perspectives

open access: yesBioEssays, Volume 47, Issue 11, November 2025.
Breathing is typically automatic, ensuring homeostasis, but it is also shaped by emotion, behavior, and volition. This review synthesizes our current understanding of the flexible neural mechanisms that enable multimodal control of breathing, emphasizing the role of pontomedullary circuits.
Nathan A. Baertsch   +4 more
wiley   +1 more source

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