Results 1 to 10 of about 1,060,164 (113)

3D Printed High‐Strength Hydrogel for Dual Release of Cu2+ and Ag+ Ions to Enhance Bone Repair and Antibacterial Properties

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Bone restoration is often hindered by the spatiotemporal dysregulation of immune and regenerative signals. Conventional bio‐inert implants, providing only passive support, fail to modulate this microenvironment, leading to infections and poor healing.
Zhizhong Sun, Yifei Wang, Yi Zheng, Minying Li, Longbao Feng, Ziwei Jiang, Hengrui Liu, Rui Guo, Weipeng Sun   +8 more
wiley   +1 more source

Ultrathin MnO2‐PEG‐PD‐L1 Nanosheets Enable Tumor Microenvironment Modulation and NIR‐II Photothermal Immunotherapy for Durable Control of Lung Cancer and Postoperative Recurrence

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Lung cancer is one of the most common and deadly malignancies worldwide. Although immune checkpoint inhibitors, including PD‐1/PD‐L1 blockers, have benefited a subset of patients, response rates remain limited, and recurrence is frequent because of the immunosuppressive tumor microenvironment (TME), characterized by hypoxia and dysregulated ...
Yi Ma, Lingxi Zhu, Yingran Shen, Yue Liu, Hugang Liu, Kunpeng Zhang, Chao Jiang   +6 more
wiley   +1 more source

Titanium Implant Abutments With Polydopamine‐Mesoporous Cerium Dioxide Coatings for Enhanced Antibacterial, Anti‐Inflammatory, and Soft Tissue Integration Properties

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT The poor soft tissue integration around titanium implants creates a microgap that serves as a pathway for pathogen invasion, resulting in infection, inflammation, and the progression of peri‐implantitis. As the implant’s transmucosal component, the abutment determines the degree of peri‐implant soft tissue attachment.
Xuan Li, Min Xing, Haoyue Liu, Kuicai Ye, Xuanyong Liu, Li Ma, Wenhao Qian, Jiajun Qiu   +7 more
wiley   +1 more source

Metal‐Doped Carbon‐Based Nanomaterials: Photothermal Mechanism Innovation and Precision Therapy Advancement in Antibacterial and Antitumor Applications

Rare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Metal‐doped carbon‐based nanomaterials (M‐CNM) play a strategically significant role in next‐generation precision antibacterial and antitumor therapies, as they integrate synergistic photothermal ablation, catalytic reactive oxygen species (ROS) generation, and multimodal imaging capabilities. However, their clinical translation is hindered by
Pengxiang Liu, Juan Du, Guoqiang Ma, Zheng Li, Aibing Chen, Senlin Hou   +5 more
wiley   +1 more source

First‐trimester prediction and prevention of preterm pre‐eclampsia in women with chronic hypertension

Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 5, Page 613-622, May 2026.
ABSTRACT Objectives To evaluate the effect of aspirin on gestational age at delivery due to preterm pre‐eclampsia (PE) in women with chronic hypertension (CH), to assess the predictive performance of the Fetal Medicine Foundation (FMF) first‐trimester competing‐risks model for preterm PE in this high‐risk group and to evaluate how parity, previous PE ...
D. L. Rolnik, S. Gil‐Pugliese, A. Syngelaki, E. Bujold, D. Wright, L. C. Poon, K. H. Nicolaides, ASPRE and SPREE Collaborators, C. de Paco Matallana, D. Janga, E. Greco, F. S. Molina, G. Papaioannou, H. Meiri, J. C. Jani, K. Maclagan, K. Tenenbaum‐Gavish, M. Singh, M. Y. Tan, N. O'Gorman, N. Persico, R. Akolekar, S. Cicero, W. Plasencia   +23 more
wiley   +1 more source

基因治疗中重组腺相关病毒载体的安全性

Zhongguo shiyan zhenduanxue, 2017
基因治疗对常用治疗方法难以解决的单基因疾病、癌症、心血管疾病等往往具有良好的疗效。迄今为止,已有超过2000例的基因治疗应用于临床试验[1],在基因治疗临床试验中超过68%是应用病毒载体。腺相关病毒（AAV）载体由于其基因传递效率高,缺乏致病性和具有良好的安全性而备受青睐[2]。三十多年来,许多应用AAV的基因治疗临床试验取得了成功,rAAV成为人类临床试验的最佳载体之一[3,4,5 ...
张梅, 于英君
doaj  

Developing HMME‐Conjugated NIR‐II Activated Carbon Dots Nanospray for the Treatment of MRSA Biofilm Infections in Diabetic Wound via PTT/CDT/SDT

Rare Metals, Volume 45, Issue 4, April 2026.
ABSTRACT Diabetic wound infections are a common complication of diabetes, which severely impact patients' quality of life. Effective treatment of diabetic wound infections remains one major challenge in the clinic, partially due to the formation of bacterial biofilm and antibiotic resistance.
Liang Zhou, Ning Wang, Zumeng Wang, Pingping Zhang, Yuqin Chu, Yingguang Liu, Wen Liu, Chengwu Zhang, Lili Yan   +8 more
wiley   +1 more source

pEgrB7.2基因联合辐射对肿瘤作用的实验研究

Zhongguo shiyan zhenduanxue, 2011
自从基因-放射治疗理论[1]确立以来,越来越多的研究人员把放射治疗和基因治疗有机结合用于恶性肿瘤的治疗。共刺激分子的基因治疗也是目前研究的热点。自从发现B7分子以来,多家实验室将该基因转染至肿瘤细胞 ...
杨建征, 金平, 王方锐, 陈玉丙, 贾晓晶, 边丽, 侯吉光, 王铁军   +7 more
doaj  

Colorimetric and Photothermal Hollow Nanocomposite Based on Silver‐Seeded Prussian Blue Analog for Dopamine Monitoring and Photothermal Sterilization

Rare Metals, Volume 45, Issue 3, March 2026.
ABSTRACT Multi‐element Prussian blue analog (PBA) nanocomposites have attracted wide attention for their superior characteristics to single‐functional nanomaterials in extensive applications of diagnosis and therapy. In this study, a novel hollow nanocomposite was designed and fabricated by embedding S2− and Ag nanoparticles into a NiCuMnFe (PBA).
Tao Ji, Ze Xu, Ying Wang, Xingchen Lu, Yuqian Zhu, Qingli Huang, Quanshuang Li, Shibao Li   +7 more
wiley   +1 more source

乙型肝炎病毒基因型检测的临床意义

Zhongguo shiyan zhenduanxue, 2010
目的探讨乙型肝炎病毒基因型分布及其对抗病毒疗效的影响。方法对183例患者进行基因分型,对应用恩替卡韦及聚乙二醇干扰素浕-2a抗病毒治疗不同基因型患者疗效进行比较。率的比较采用χ2检验。结果183例慢性乙肝患者以C基因型为主,占53.6%,其次为B基因型（35.5%）,C基因型患者HBeAg阳性率（69.4%）明显高于B基因型患者（47.7 ...
徐严, 张永贵, 季尚玮, 王江滨
doaj