Results 21 to 30 of about 1,060,164 (113)
Zhongguo shiyan zhenduanxue, 2009 目的分析局部注射和肝动脉给予血管抑素基因（Angiostatin）和内皮抑素基因（Endostatin）重组质粒对大鼠肝癌治疗效果的差异。方法将肝癌模型大鼠随机分为:局部治疗组、局部对照组、肝动脉治疗组、肝动脉对照组。治疗组给予200μL质粒和脂质体复合物和对照组给予生理盐水200μL。治疗后观测肿瘤大小、微血管密度、血管内皮生长因子、肿瘤凋亡指标的变化。结果6d开始基因治疗组各治疗指标与对照组相比均具有统计学差异 ...
谢耀萍, 杨志杰, 李勇, 马铎
doaj
New Advances of Degradable Magnesium‐Based Metal Biomaterials in the Field of Orthopedics
Rare Metals, Volume 45, Issue 2, February 2026.ABSTRACT Based on their outstanding biomechanical properties and superior osteogenic activity, magnesium (Mg) and its alloys have been extensively investigated for their biocompatibility and therapeutic efficacy in treating fractures and bone defects.
Jia‐Nan Yu +8 more
wiley +1 more source
, 2012 目的观察益气养阴、活血祛瘀中药联合西药治疗早期糖尿病肾病的疗效。方法将早期糖尿病肾病患者46例随机分为2组,治疗组23例,采用基础治疗方案加用益气养阴、活血祛瘀中药治疗,对照组23例仅采用基础方案治疗,2组均治疗8周。结果治疗组总有效率为87%,对照组总有效率为70%,2组比较有显著性差异 ...
陈敏, 俞翔
core
Linchuang shenzangbing zazhi, 2019 目的观察慢性肾衰竭维持性血液透析（MHD）患者在N5,N10-亚甲基四氢叶酸还原酶（MTHFR）基因多态性指导下的个体化服用叶酸治疗纠正高同型半胱氨酸血症的效果。方法研究纳入93例一般状况稳定的MHD患者,分为普通治疗组和个体化治疗组。两组患者均行低通量透析,并在研究期间透析器和血流量保持前后稳定。在透析治疗基础上,普通治疗组患者均口服叶酸15 mg/d,个体化治疗组依据患者MTHFR基因型决定叶酸用量,纯合子突变型（TT）、杂合子突变型（CT）和野生型（CC）患者分别口服叶酸剂量为30 mg/d、15
CHAI Lin +3 more
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Ultrasound in Obstetrics &Gynecology, Volume 67, Issue 2, Page 162-167, February 2026.ABSTRACT Objective Pre‐eclampsia (PE) is a leading cause of maternal and neonatal morbidity and mortality worldwide. Early identification of high‐risk pregnancies in the first trimester allows preventive treatment with low‐dose aspirin. This study aimed to evaluate whether multivariable Gaussian algorithm‐based PE screening strategies, with and without
E. Bonacina +10 more
wiley +1 more source
Zhongguo shiyan zhenduanxue, 2008 目的探讨缺氧诱导因子（HIF-1α）基因治疗家兔肢体缺血模型的疗效。方法在家兔缺血模型的肢体内注射携带/HIF-1α基因的重组腺病毒AdHIF-1α,检测HIF-1α基因在缺血肌组织中表达情况,并观察其生物学特点。实验以携带GFP基因的重组腺病毒AdGFP为对照。结果免疫组化染色均检测到HIF-1α的表达。转AdHIF-1α基因治疗组毛细血管计数及小动脉计数均高于AdGFP转导的对照组 ...
孙晓峰 +5 more
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Negotiating Centralization: How Local Networks Reshaped Scotland's National Care Service Reform
Politics &Policy, Volume 54, Issue 1, February 2026.ABSTRACT Centralizing reforms frequently diverge from their original designs, yet the processes through which this divergence occurs remain insufficiently understood. This article examines Scotland's National Care Service reform (2021–2025), a major recentralization that underwent significant modification following sustained engagement from local ...
Awais Mashkoor
wiley +1 more source
通过主动诱导移植物抗宿主病使AML1-ETO基因转阴1例并文献复习
Zhongguo shiyan zhenduanxue, 2023 异基因造血干细胞移植(allo-HSCT)是目前高危组急性髓系白血病(AML)唯一可以根治的治疗手段[1]。然而，移植后复发仍是allo-HSCT后患者死亡的最主要原因[2]。通过微小残留病(MRD)监测及时发现MRD并给予抢先治疗可以有效预防移植后复发，提高长期生存率[3]。目前对于移植后MRD阳性患者的干预手段主要有供者淋巴细胞输注(DLI)、去甲基化治疗、靶向药物治疗、干扰素(IFN)等，但仍有部分患者疗效不佳[4-5]。
吴小清 +4 more
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Veterinary Dermatology, Volume 37, Issue 1, Page 34-44, February 2026.Background: The chronic and multifactorial character of canine atopic dermatitis (cAD) often leads to poor disease control and treatment dissatisfaction. Environmental factors are likely to contribute to the disease development and may play a more important role than assumed previously.
Patricia Clara‐Maria Rhodius +11 more
wiley +1 more source
重组人表皮生长因子在光子嫩肤治疗仪治疗雀斑中的应用价值分析 [PDF]
, 2018 目的分析重组人表皮生长因子在光子嫩肤治疗仪治疗雀斑中的应用价值。方法对照组采用常规方法治疗,观察组采用重组人表皮生长因子治疗。结果观察组愈合时间(6.85±0.51)d、结痂(7.15±0.45)d、结痂脱落(9.98±0.74)d、有效率97.73%、美观性满意度93.18%、舒适性满意度95.45%、生活质量(92.80±1.96)分,与对照组相比差异显著(P
纪卡莉, 许春鹏
core +1 more source