Results 21 to 30 of about 764,729 (160)

Ultrasound‐Driven Dual Piezocatalytic–Electrical Scaffold Synergistically Promotes Osteoporotic Bone Healing

open access: yesRare Metals, Volume 45, Issue 8, August 2026.
ABSTRACT The regeneration of osteoporotic bone defects is severely hampered by compromised endogenous healing capacity, demanding advanced strategies that actively orchestrate pro‐osteogenic microenvironments. Here, we report an integrated, self‐powered osteo‐regenerative system that uniquely leverages a dual ultrasound‐responsive piezoelectric ...
Bing Tan   +6 more
wiley   +1 more source

Uncovering correlates of decline and critical refuges for a threatened terrestrial mammal

open access: yesConservation Biology, Volume 40, Issue 4, August 2026.
Abstract Globally, the geographic ranges of numerous species are contracting. Identifying spatiotemporal patterns of threat impact can illuminate why species decline in some parts of their range but persist in others. We developed a correlative approach to identify species’ response thresholds and locate ecological refuge areas associated with ...
Natalya M. Maitz   +5 more
wiley   +1 more source

Examining the multi‐disciplinary origins of biophobia towards threatening and non‐threatening wildlife in a highly urbanised city in China

open access: yesPeople and Nature, Volume 8, Issue 7, Page 2338-2352, July 2026.
Abstract Urbanisation is reshaping how people experience wildlife, reducing our shared spaces with local biodiversity. Fewer opportunities for human–wildlife interactions weaken our emotional attachments to nature and precipitate a loss of species knowledge and familiarity.
Sam S. S. Lau   +3 more
wiley   +1 more source

An Organo‐Pt(II) Photosensitizer With Robust Photo‐Assisted Antibacterial and Wound Recovery Performances in Diabetic Mice Wound Model

open access: yesRare Metals, Volume 45, Issue 7, July 2026.
ABSTRACT The pathogenesis of diabetic foot ulcers is complex, often involving polymicrobial infection and persistent inflammatory responses, which lead to delayed or nonhealing wounds, posing a formidable clinical challenge. Existing photodynamic therapy reagents and traditional treatments generally address only a single pathological aspect, and the ...
Yu Zhang   +16 more
wiley   +1 more source

Ultrathin MnO2‐PEG‐PD‐L1 Nanosheets Enable Tumor Microenvironment Modulation and NIR‐II Photothermal Immunotherapy for Durable Control of Lung Cancer and Postoperative Recurrence

open access: yesRare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Lung cancer is one of the most common and deadly malignancies worldwide. Although immune checkpoint inhibitors, including PD‐1/PD‐L1 blockers, have benefited a subset of patients, response rates remain limited, and recurrence is frequent because of the immunosuppressive tumor microenvironment (TME), characterized by hypoxia and dysregulated ...
Yi Ma   +6 more
wiley   +1 more source

ABCA12 Frameshift Deletion in Domestic Cats With Ichthyosis Fetalis

open access: yesVeterinary Dermatology, Volume 37, Issue 3, Page 365-374, June 2026.
ABSTRACT Background Ichthyosis fetalis (IF), also known as harlequin ichthyosis, is a rare and often fatal autosomal recessive congenital skin disorder. It is characterized by thickened, hard skin plaques and deep skin fissures that limit mobility and cause malformations of the eyes, lips and ears.
Jeanna M. Blake   +2 more
wiley   +1 more source

An Ultrasound‐Triggered Antibacterial Hydrogel With Integrated Antioxidant and Angiogenic Functions for Infected Wound Care

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Managing diabetic wounds requires simultaneously addressing their infectious, oxidative, and regenerative impairments. To address this, this study integrates a piezoelectric BiOCl@CuSe heterojunction (PFM‐verified) into an injectable F127/HA hydrogel, creating an ultrasound‐responsive smart dressing.
Jiayan Guo   +5 more
wiley   +1 more source

A Dual‐Function Mitochondria‐Targeted Polyoxometalate Nanomicelle Boosts Pyroptosis‐Dependent Antitumor Immune Response in Triple‐Negative Breast Cancer

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT The efficacy of immunotherapy in triple‐negative breast cancer (TNBC) is often limited, whereas the immunotherapeutic potential of pyroptosis is frequently undermined by a compensatory surge in mitophagy. To address this challenge, this study developed a reactive oxygen species (ROS)‐responsive and mitochondria‐targeted nanomicelle (POM@CTT ...
Qingqing Dou   +6 more
wiley   +1 more source

体内实验研究神经节苷脂对小鼠迟发型变态反应的影响

open access: yesZhongguo shiyan zhenduanxue, 2006
目的探讨神经节苷脂对小鼠迟发型变态反应的作用。方法体内利用肿瘤相关抗原皮下注射到小鼠背部皮下,每周一次,连续三周,使小鼠致敏,第四周对小鼠进行激发试验,刺激产生迟发型变态反应,即将表皮郎格罕氏细胞与神经节苷脂和肿瘤相关抗原共同孵育后注射到小鼠后足掌侧,分别于注射后24,48小时测量足掌肿胀程度来评估神经节苷脂对小鼠迟发型变态反应的作用。结果神经节苷脂可降低小鼠足掌肿胀程度,抑制小鼠迟发型变态反应。结论神经节苷脂具有抑制小鼠迟发型变态反应,同时说明神经节苷脂可以抑制表皮郎格罕氏细胞抗原提呈作用。
孙晶, 李玉林, 李一雷
doaj  

Aspect Ratio‐Controlled Chiral Nanostructures for Dual‐Mode Breast Cancer Theranostics

open access: yesRare Metals, Volume 45, Issue 5, May 2026.
ABSTRACT Chiral CdSe/CdS quantum dots (QDs) have emerged as promising platforms for precise cancer diagnosis and therapy due to their unique optical properties and biological interactions. In this study, we systematically investigated the role of aspect ratio (AR) modulation in ultrathin‐shelled chiral CdSe/CdS dot‐in‐rods (DRs) on their performance in
Linxuan Wu   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy