Results 11 to 20 of about 3,087 (179)
Abstract Conservation of migratory species exhibiting wide‐ranging and multidimensional behaviors is challenged by management efforts that only utilize horizontal movements or produce static spatial–temporal products. For the deep‐diving, critically endangered eastern Pacific leatherback turtle, tools that predict where turtles have high risks of ...
Nicole Barbour +8 more
wiley +1 more source
We apply an integrative perspective to modelling current and future land‐use change in Kuantan, Malaysia, a location with highly biodiverse forests, and also a hotspot of land‐use change. The region is representative of the types of development challenges faced by countries in Southeast Asia, which are also biodiversity hotspots.
Sharun Beream Nasir +5 more
wiley +1 more source
Abstract Development and implementation of effective protected area management to reduce deforestation depend in part on identifying factors contributing to forest loss and areas at risk of conversion, but standard land‐use‐change modeling may not fully capture contextual factors that are not easily quantified.
Katherine Siegel +5 more
wiley +1 more source
High-performance liquid chromatography-mass spectrometry-based acetylcholinesterase assay for the screening of inhibitors in natural medicinal plants [PDF]
酶是治疗多种疾病的重要靶标,乙酰胆碱酯酶(AChE)的抑制剂是现阶段治疗阿尔兹海默症(AD)最有效的一类药物。从天然产物中寻找适宜患者长期服用、毒副作用小、作用面广等优点的乙酰胆碱酯酶抑制剂(AChEIs)受到了科研工作者的广泛关注。本论文以AChE作为药物靶标,构建基于高效液相色谱-质谱联用技术(HPLC-MS)的在线生物活性检测方法,发展集分离纯化、结构确证和活性筛选于一体的活性导向天然产物研究方法,用来寻找和发现天然药用植物中潜在的AChEIs候选化合物 ...
刘静兰
core
Harnessing social media data to track species range shifts
Abstract Biodiversity monitoring programs and citizen science data remain heavily biased toward the Global North. Especially in megadiverse countries with limited biodiversity records, incorporating social media data can help address existing data gaps.
Shawan Chowdhury +15 more
wiley +1 more source
The Role of BIN1 in Alzheimer’s Disease [PDF]
阿尔茨海默症(Alzheimer’sdisease,AD)是与年龄相关的神经退行性疾病,其主要的病理学特征为由β-淀粉样蛋白(-amyloid,Aβ)聚集产生的老年斑(senileplaues,SP)以及由异常磷酸化的tau蛋白组成的神经纤维缠结(neurofibrillarytangles,NFTs)。Aβ是由淀粉样前体蛋白(-amyloidprecursorprotein,APP)经过β-分泌酶和γ-分泌酶的依次顺序剪切而产生 ...
牛萌萌
core
Effects of Different Concentrations of Alcohol On Spatial Learning and Memory Ability and Hippocampal GFAP/NEUN in Mice [PDF]
目的 探究长期饮酒对小鼠行为学能力以及空间学习记忆能力的影响。方法 雄性KM小鼠45只,随机分成对照组(Con),低剂量组(Low)和高剂量组(High)。分别每天对照组0.10 ml/10 g自来水,低剂量组0.05 ml/10 g的56度红星二锅头,高剂量组0.10 ml/10 g的56度红星二锅头进行灌胃。连续灌胃13 d后进行衣架实验测行为学能力,最后取海马做免疫荧光染色观察海马神经元和星形胶质细胞。结果衣架实验得分,自主活动数值总体显示Low组高于其他两组,而且与Con组差异显著 ...
夏天 +7 more
core +1 more source
Abstract Henry George advocated for capturing land value increases for public ends. The active approach of public authorities organizing and financing land development can help capture higher land value increases, as Hartman and Spit indicate. However, this approach hardly happens in developing countries, where the coalition of private developers and ...
Nannan Xu
wiley +1 more source
The Expression of PolySia/TriSia Associated Proteins and Genes on Developing Brain and the Effect of Dietary Sialic Acid Intervention in Piglets [PDF]
摘要 研究背景:唾液酸(Sialicacid,Sia)是一类九碳单糖神经氨酸的总称,在细胞表面发挥其多种生物学功能。在体内,Sia通常以游离唾液酸、聚唾液酸(多聚/寡聚)、唾液酸衍生物(糖蛋白,糖脂)这三种形式存在。多聚唾液酸(polySialicacid,ploySia),一种唾液酸残基通过α2-8键连接而成的线性聚合物,广泛分布于在哺乳动物神经系统中,它的主要蛋白载体是神经细胞粘附因子(Neuralcelladhesionmolecule,NCAM)。PolySia-NCAM在细胞迁移、神经突生长 ...
任贺
core
US Foreign Policy and the Gulf States: Changing Dynamics in a Multipolar World
ABSTRACT This article focuses on US foreign policy toward the Gulf from Obama's Pivot to Asia to the initial period of the second Trump administration. It situates the role of the US within the broader context of the global energy transition and the Gulf states as geopolitical actors in a multipolar world order.
Steven Wright
wiley +1 more source

