Results 181 to 190 of about 50,268 (236)

Design, synthesis and anti-cancer activity of novel 1,2,3-triazole hybrids of erlotinib against cervical cancer via MAPK signaling pathway. [PDF]

Sci Rep
Wang L, Hou X, Huang M, He B, Mao L, Hu Z, Li L, Guo J, Peng L.   +8 more
europepmc   +1 more source

Mitigating Antimicrobial Resistance through Strategic Design of Multimodal Antibacterial Agents Based on 1,2,3-Triazole with Click Chemistry. [PDF]

ACS Bio Med Chem Au
Chathangad SN, Vijayan VN, George JA, Sadhukhan S.   +3 more
europepmc   +1 more source

1-Phenyl-β-carboline-3-carboxamide-1,2,3-triazole-N-phenylacetamide hybrids as new α-glucosidase inhibitors. [PDF]

Sci Rep
Safaie E, Sayahi MH, Dastyafteh N, Halimi M, Noori M, Mohammadi-Khanaposhtani M, Zonouzi A, Mirzazadeh R, Tajmir-Riahi A, Mojtabavi S, Faramarzi MA, Larijani B, Asadi M, Mahdavi M.   +13 more
europepmc   +1 more source

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Synthesis and Characterization of Azido-Functionalized 1,2,3-Triazole and Fused 1,2,3-Triazole

The Journal of Organic Chemistry, 2023
Here, we report the nitration of NH on the 1,2,3-triazole ring and the synthesis of several nitrogen-rich energetic compounds based on key intermediate 4-azido-5-(chlorodinitromethyl)-2-nitro-2H-1,2,3-triazole (5). Starting from 4-amino-1H-1,2,3-triazole-5-carbonitrile (1), we successfully constructed compound 5 through four steps.
Yupeng Cao, Haifeng Huang, Limin Wang, Xiangyang Lin, Jun Yang   +4 more
openaire   +2 more sources

Synthesis of 1,2,3‐Triazoles.

ChemInform, 2004
AbstractFor Abstract see ChemInform Abstract in Full Text.
Dolly Dolly, Belen Batanero, Fructuoso Barba   +2 more
openaire   +2 more sources

Benzylated 1,2,3-triazoles as anticoccidiostats

Journal of Medicinal Chemistry, 1991
Substituted 5-amino-4-carbamoyl-1,2,3-triazoles 3a-w were prepared by two synthetic schemes and evaluated in vivo for anticoccidial activity. Both schemes proceeded by brominating appropriately substituted toluenes 4a-s,v to 5a-s,v. In Scheme I, the brominated benzyl analogues 5 were converted to the corresponding benzyl azides 6, which were treated ...
R J, Bochis, J C, Chabala, E, Harris, L H, Peterson, L, Barash, T, Beattie, J E, Brown, D W, Graham, F S, Waksmunski, M, Tischler   +9 more
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Mesoionic 1,2,3-Triazoles and 1,2,3-Triazole Carbenes

2014
Routine access to 1,2,3-triazoles through the copper-catalyzed azide-alkyne “click” cycloaddition reaction has promoted the rapid development of 1,2,3-triazolylidenes as ligands for transition metals. The organometallic complexes containing this kind of N-heterocyclic carbene ligands (NHCs) have shown to possess unique structural characteristics ...
Jesus M. Aizpurua, Maialen Sagartzazu-Aizpurua, Zaira Monasterio   +2 more
openaire   +1 more source

1,2,3-Triazoles

1974
Publisher Summary This chapter focuses on the chemistry of monocyclic1,2,3-triazoles as much of the chemistry of benzotriazoles and other fused systems has little in common with monocyclic triazole chemistry and provides a broad survey of methods of synthesis and reactions of triazoles. There has been considerable interest in 1,2,3-triazoles as light
T.L. Gilchrist, G.E. Gymer
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1,2,3‐Triazoles

ChemInform, 2005
AbstractFor Abstract see ChemInform Abstract in Full Text.
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Synthesis of 1,2,3‐Triazole Analogues of Lincomycin

Helvetica Chimica Acta, 2008
AbstractIn search for new antibiotics we replaced the amide moiety of lincomycin 1 by a 1,2,3‐triazole ring. The 1,2,3‐triazoles 10a–10k were obtained as single regioisomers by ‘click reaction’ of azide 5 with the alkyne 9k, derived from propyl hygric acid, and the alkyl, aryl, or cycloalkyl alkynes ribosomes 9a–9j.
Collin, M P, Hobbie, S N, Böttger, E C, Vasella, A   +3 more
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