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Mass spectra of 1,2,3-triazoles
Journal of the Chemical Society, Perkin Transactions 1, 1979The mass spectra of substituted 1,2,3-triazoles [RTR′, (1)](R′= H, CO2X, COR″, pyrazolyl, or isoxazolyl) are discussed. For a wide variety of structural types, P+ is always strong and [P+ 1]+ is often of significant intensity. Subsequent breakdown patterns are strongly dependent on the substituents R and R′.
Sidney I. Miller +2 more
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A vibrational assignment for 1,2,3-triazole
Journal of the Chemical Society B: Physical Organic, 1969I.r. spectra of 1,2,3-triazole in the vapour and liquid states and in solution are reported and discussed. From these, and by comparison with the spectra of other simple five-membered heterocycles, vibrational assignments are proposed. The i.r. spectra is satisfactorily interpreted in terms of an asymmetric structure.
E. Borello +2 more
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1,2,3‐Triazoles in Peptidomimetic Chemistry
European Journal of Organic Chemistry, 2011AbstractThe ability to synthesise small peptidomimetics that mimic the secondary structure of proteins is an ever expanding area of research directed at sourcing new medicinal agents and biological probes. A significant current challenge is to mimic protein epitopes under physiological conditions using small peptidomimetics that are easy to prepare ...
Pedersen, D., Abell, A.
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Azolyl-substituted 1,2,3-triazoles
Russian Journal of Organic Chemistry, 2016Huisgen reaction of (E)-1,5-diarylpent-2-en-4-yn-1-ones and (E)-1,5-diarylpent-1-en-4-yn-3-ones afforded 1-aryl-3-(5-aryl-1H-1,2,3-triazol-4-yl)prop-2-en-1-ones and 3-aryl-1-(5-aryl-1H-1,2,3-triazol-4-yl)-prop-2-en-1-ones, respectively. (E)-1-Aryl-3-(5-phenyl-1H-1,2,3-triazol-4-yl)prop-2-en-1-ones reacted with hydrazine hydrate and phenylhydrazine to ...
A. A. Golovanov +7 more
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ChemInform Abstract: 1,2,3‐TRIAZOLES
Chemischer Informationsdienst, 1974AbstractIn einer Zusammenfassung wird die Synthese der verschiedenen 1,2,3‐Triazole aus Aziden mit Acetylenen oder aktivierten Methylenverbindungen und ausgehend von α‐Diketonen oder α‐Diketonderivaten er1äutert,und die Struktur, die physikalischen Eigenschaften sowie die chemischen Reaktionsweisen der Triazole bei Substitutionsreaktionen, Umwandlung ...
T. L. GILCHRIST, G. E. GYMER
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Synthesis of 2H-1,2,3-Triazoles
2014This chapter gives an overview of methods for the synthesis of NH- and N(2)-substituted 1,2,3-triazoles, their advantages, lacks, scope, and limitations. Moreover, it will give some insights on the reaction mechanisms and will explain how different conditions and structure substrates can influence the direction for reactions.
Nataliya Belskaya +2 more
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Pharmacological Significance of 1,2,3-Triazoles
Click chemistry is not a single specific reaction, but was meant to mimic nature, which also generates substances by joining small modular units. The 1,3-dipolar azide, alkyne cycloaddition (CuAAC) reaction catalyzed by copper, as nearly quantitative and easy to execute has emerged as the leading example of “click chemistry”.Mubarak Hanif Shaikh +3 more
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