Results 11 to 20 of about 976 (164)

Synthesis of functionalized imidazo[4,5-e]thiazolo[3,2-b]triazines by condensation of imidazo[4,5-e]triazinethiones with DMAD or DEAD and rearrangement to imidazo[4,5-e]thiazolo[2,3-c]triazines

Beilstein Journal of Organic Chemistry, 2021
Two series of functionalized imidazothiazolotriazine derivatives were synthesized via the condensation of imidazo[4,5-e]-1,2,4-triazine-3-thiones with acetylenedicarboxylic acid dimethyl and diethyl esters (DMAD and DEAD) and subsequent base-catalyzed ...
Alexei N. Izmest’ev, Dmitry B. Vinogradov, Natalya G. Kolotyrkina, Angelina N. Kravchenko, Galina A. Gazieva   +4 more
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The Reaction of 1,6-Diamino-4-aryl-2-oxo-1,2-dihydropyridine- 3,5-Dicarbonitriles with Certain Electrophilic Agents

Chemistry Proceedings, 2023
The reaction of 1,6-diamino-2-oxo-1,2-dihydropyridine-3,5-dicarbonitriles, which are easily available through the reaction of cyanoacetohydrazide with arylmethylene malononitriles, with ninhydrin leads to the formation of novel dihydroindeno[1,2-e]pyrido[
Alexei A. Dolganov, Alexandra R. Chikava, Victor V. Dotsenko   +2 more
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Synthesis and properties of 3-(ethylthio)-9-methyl-6-(alkylthio)pyrazolo[1,5-d][1,2,4]triazolo[3,4-f][1,2,4]triazines

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2022
The combination of pyrazole and 1,2,4-triazole fragments in one structure makes it possible to achieve some success in creating potential biologically active compounds. Various factors contribute to this process.
S. O. Fedotov, A. S. Hotsulia
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Eco-friendly plant growth and development regulators on the basis of derivatives 1,2,4-triazines [PDF]

BIO Web of Conferences, 2021
The article considers the application of plant growth and development regulators, in particular, derivatives of asymmetric triazines. A method for obtaining hexahydro-1,2,4-triazinone-3 is given.
Builova E.A., Mazitova A.K., Aminova G.K., Zaripov I.I., Alibakova A.H.   +4 more
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3-Methylsulfanyl-5-phenyl-1,2,4-triazine [PDF]

Acta Crystallographica Section E Structure Reports Online, 2014
In the molecule of the title compound, C10H9N3S, the dihedral angle between the triazine and phenyl rings is 11.77 (7)°. In the crystal, molecules are linked by π–π stacking interactions [centroid–centroid distances = 3.7359 (3) and 3.7944 (4) Å], forming layers parallel to thebcplane.
Salha Hamri, Abderrafia Hafid, Mostafà Khouili, Lahcen El Ammari, El Mostafa Ketatni   +4 more
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Combinatorial approach to the synthesis of substituted 1,2,4-triazines

Chimica Techno Acta, 2017
This article describes a convenient and easy method of substitution of the nitrile group in 5-cyano-1,2,4-triazines with the aim of obtaining of libraries of substituted 1,2,4-triazines (about 500 compounds).
D. N. Kozhevnikov, V. N. Kozhevnikov
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Review of the Synthesis and Anticancer Properties of Pyrazolo[4,3-e][1,2,4]triazine Derivatives

Molecules, 2020
This review focuses on the cytotoxic effect of new synthetic pyrazolo[4,3-e][1,2,4]triazine derivatives against different tumor cell lines. Some annulated pyrazolotriazines i.e., pyrazolo[4,3-e][1,2,4]triazolo[4,3-b][1,2,4]triazines and pyrazolo[4,3-e ...
Zofia Bernat, Anna Szymanowska, Mateusz Kciuk, Katarzyna Kotwica-Mojzych, Mariusz Mojzych   +4 more
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Bioactive Pyrrolo[2,1-f][1,2,4]triazines: Synthesis, Molecular Docking, In Vitro Cytotoxicity Assay and Antiviral Studies

Chemistry, 2023
A series of 2,4-disubstituted pyrrolo[2,1-f][1,2,4]triazines containing both aryl and thienyl substituents were synthesized by exploiting the 1,3-cycloaddition reaction of N(1)-ethyl-1,2,4-triazinium tetrafluoroborates with dimethyl ...
Nataliya N. Mochulskaya, Svetlana K. Kotovskaya, Ilya I. Butorin, Mikhail V. Varaksin, Valery N. Charushin, Vladimir L. Rusinov, Yana L. Esaulkova, Alexander V. Slita, Polina A. Ilyina, Vladimir V. Zarubaev   +9 more
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The synthesis of 1,2,4-triazines bearing the residues of higher alcohols in the 5-position via the ipso-substitution of cyano group under the solvent-free conditions

Chimica Techno Acta, 2017
A convenient method for the obtaining of 3,6-diaryl-1,2,4-triazines substituted with  residues of higher alcohols in the position of C5 via the ipso-substitution of cyano group in under the solvent free conditions was reported.
A. P. Krinochkin, D. S. Kopchuk, E. S. Starnovskaya, Ya. K. Shtaiz, A. F. Khasanov, I. S. Kovalev, O. S. Taniya, G. V. Zyryanov, V. L. Rusinov, O. N. Chupakhin   +9 more
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Efficient Routes to Pyrazolo[3,4-e][1,2,4]triazines and a New Ring System: [1,2,4]Triazino[5,6-d][1,2,3]triazines

Molecules, 2010
Arylhydrazonomalononitriles 1a,b react with phenylhydrazine to yield amidrazones 2a,b that cyclize to give 2-aryl-5-phenylhydrazono-2,5-dihydro-[1,2,4]-triazine-6-carbonitriles 5a,b upon reaction with dimethylformamide dimethylacetal (DMFDMA).
Hamad Mohamed Al-Matar, Khaled Dessouky Khalil, Doa’a Mohamed Al-Dorri, Mohamed Helmy Elnagdi   +3 more
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