Results 31 to 40 of about 2,636 (208)

Ring Cleavage of Some Bicylic Compounds Derived from 1,2,4-Triazine [PDF]

Iranian Journal of Chemistry & Chemical Engineering, 1995
Ring cleavage occurred when 1,2,4-triazino-1,2,4-triazines (3), (4) and (5) were treated with concentrated hydrochloric acid to yield N-substituted triazines (7) and (8). These confirm the given configuration assigned to the isomeric triazinotriazines. 6-
Majid M. Heravi, Mehdi Bakavoli, Zohreh Sadjadi Hashemi   +2 more
doaj  

Synthesis and Photophysical Properties of α-(N-Biphenyl)-Substituted 2,2′-Bipyridine-Based Push–Pull Fluorophores

Molecules, 2022
A series of new α-(N-biphenyl)-substituted 2,2′-bipyridines were obtained through the combination of the ipso-nucleophilic aromatic substitution of the C5-cyano group, aza-Diels–Alder and Suzuki cross-coupling reactions, starting from 5-cyano-1,2,4 ...
Ekaterina S. Starnovskaya, Dmitry S. Kopchuk, Albert F. Khasanov, Olga S. Taniya, Igor L. Nikonov, Maria I. Valieva, Dmitry E. Pavlyuk, Alexander S. Novikov, Grigory V. Zyryanov, Oleg N. Chupakhin   +9 more
doaj   +1 more source

Development of a Mild and Versatile Directed Cycloaddition Approach to Pyridines [PDF]

, 2014
The aza-Diels–Alder cycloaddition of 1,2,4-triazines with alkynes offers a rapid and convenient method for the synthesis of highly substituted pyridines, but often requires harsh conditions and long reaction times.
Boger, Browne, Crépin, Delaney, Diring, Foster, Hall, Helm, Henry, Hill, Hilt, Jones, Kirkham, Konno, Moore, Raw, Varela, Vedejs, Vivat, Ye   +19 more
core   +1 more source

Revisiting the structure and chemistry of 3(5)-Substituted Pyrazoles [PDF]

, 2019
Pyrazoles are known as versatile scaffolds in organic synthesis and medicinal chemistry, often used as starting materials for the preparation of more complex heterocyclic systems with relevance in the pharmaceutical field.
Alam, Alina Secrieru, Alkorta, Andes, Anwar, Behr, Brown, Castillo, Catalan, Chauhan, Clark, Elguero, Elnagdi, Favre, Fichez, Hall, Horta, Katritzky, Katritzky, Kost, Kumar, Larina, Maria Lurdes Santos Cristiano, Mert, Minkin, Minkin, Mohamed, Nagy, Nimbalkar, Paul Michael O’Neill, Schofield, Simons, Szajda, Taylor, Zerbi   +34 more
core   +2 more sources

A facile route for the synthesis of novel S-linked 1,3,5-triazine tethered peptidomimetics [PDF]

, 2014
An efficient one-pot synthesis of Nα-protected S-linked 1,3,5-triazine tethered peptidomimetics is described. The protocol involves a three-component condensation reaction employing Nα-protected amino alkyl isothiouronium salt, formaldehyde and amino ...
Basavaprabhu, ., Krishnamurthy, M., Sharanabai, K.M., Sureshbabu, V.V.   +3 more
core   +1 more source

3-[4-(1H-indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, nortopsentin Analogues with antiproliferative activity [PDF]

, 2015
A new series of nortopsentin analogues, in which the imidazole ring of the natural product was replaced by thiazole and the indole unit bound to position 2 of the thiazole ring was substituted by a 7-azaindole moiety, was efficiently synthesized.
Attanzio, A., Barraja, P., Carbone, A., Ciancimino, C., Cirrincione, G., Di Vita, G., Diana, P., Livrea, M., Montalbano, A., Parrino, B., Span\uf2, V., Tesoriere, L.   +11 more
core   +2 more sources

6-Amino-3,4-dimethyl-1,2,4-triazin-1-ium 2-anilinobenzoate–3-amino-5,6-dimethyl-1,2,4- triazine (1/1) [PDF]

, 2017
In the title molecular salt, C5H9N4 + C13H10NO2 C5H8N4, the asymmetric unit consists of a 6-amino-3,4-dimethyl-1,2,4-triazin-1-ium cation, a 2-anilinobenzoate anion and a neutral 3-amino-5,6-dimethyl-1,2,4-triazine molecule.
Balasubramani, Kasthuri, Razak, Ibrahim Abdul, Sangeetha, Ramalingam, Thanigaimani, Kaliyaperumal   +3 more
core   +3 more sources

A Direct Route to 6,6’-Disubstituted-2,2’-Bipyridines by Double Diels-Alder/retro Diels-Alder Reaction of 5,5’-bi-1,2,4-Triazines

Molecules, 2005
Inverse electron demand Diels-Alder reaction of functionalized 5,5’-bi-1,2,4- triazines with bicyclo[2.2.1]hepta-2,5-diene in boiling p-cymene leads to a range of 6,6’- disubstituted-2,2’-bipyridines in good yield.
D. Branowska
doaj   +1 more source

5,6-Dimethyl-1,2,4-triazin-3-amine [PDF]

Acta Crystallographica Section E Structure Reports Online, 2011
In the crystal structure of the title compound, C(5)H(8)N(4), adjacent mol-ecules are connected through N-H⋯N hydrogen bonds, resulting in a zigzag chain along [100]. The amino groups and heterocyclic N atoms are involved in further N-H⋯N hydrogen bonds, forming R(2) (2)(8) motifs.
Man-Hua Wu, Qi-Ming Qiu, Sen Gao, Qiong-Hua Jin, Cun-Lin Zhang   +4 more
openaire   +3 more sources

Microwave Assisted Synthesis of Some New Fused 1,2,4-Triazines Bearing Thiophene Moieties With Expected Pharmacological Activity

Molecules, 2011
Rapid and efficient solvent-free synthesis of 4-amino-3-mercapto-6-[2-(2-thienyl)vinyl]-1,2,4-triazin-5(4H)-one 1 under microwave irradiation is described. Some new fused heterobicyclic nitrogen systems such as 1,2,4-triazino[3,4-b][1,3,4]thiadiazinones,
Mosselhi A. Mosselhi, Mohamed M. Youssef, Hosam A. Saad   +2 more
doaj   +1 more source