Results 31 to 40 of about 29,220 (210)
Expedient synthesis of 1,2,4-triazinyl substituted benzo[c]coumarins via double oxidation strategy
Chimica Techno Acta, 2023 Herein, we report a convenient one-pot synthesis of 1,2,4-triazinyl derivatives of benzocoumarins. The proposed approach consists in the nucleophilic addition of tetrahydrobenzo annulated dimethoxycoumarin to 1,2,4-triazines followed by double oxidation ...
Ramil F. Fatykhov +6 more
doaj +1 more source
Beilstein Journal of Organic Chemistry, 2021 Two series of functionalized imidazothiazolotriazine derivatives were synthesized via the condensation of imidazo[4,5-e]-1,2,4-triazine-3-thiones with acetylenedicarboxylic acid dimethyl and diethyl esters (DMAD and DEAD) and subsequent base-catalyzed ...
Alexei N. Izmest’ev +4 more
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Discovery of 5,6-diaryl-1,2,4-triazines hybrids as potential apoptosis inducers. [PDF]
Eur J Med Chem, 2017 A series of 5,6-diaryl-1,2,4-triazines hybrids bearing a 1,2,3-triazole linker were synthesized by molecular hybridization strategy and evaluated for antiproliferative activity against three selected cancer cell lines (MGC-803, EC-109 and PC-3).
Fu DJ +14 more
europepmc +2 more sources
Chemistry Proceedings, 2023 The reaction of 1,6-diamino-2-oxo-1,2-dihydropyridine-3,5-dicarbonitriles, which are easily available through the reaction of cyanoacetohydrazide with arylmethylene malononitriles, with ninhydrin leads to the formation of novel dihydroindeno[1,2-e]pyrido[
Alexei A. Dolganov +2 more
doaj +1 more source
, 2022 A transition-metal-free [2 + 1 + 3] cycloaddition of trifluoroacetaldehyde N-sulfonylhydrazone and hexahydro-1,3,5-triazine was described. This operationally simple protocol provides a general synthesis of diverse trifluoromethylated 2,3,4,5-tetrahydro-1,
Qihao Jin +7 more
core +1 more source
Eco-friendly plant growth and development regulators on the basis of derivatives 1,2,4-triazines [PDF]
BIO Web of Conferences, 2021 The article considers the application of plant growth and development regulators, in particular, derivatives of asymmetric triazines. A method for obtaining hexahydro-1,2,4-triazinone-3 is given.
Builova E.A. +4 more
doaj +1 more source
, 2023 A direct dearomative [4 + 2] annulation of electron-poor N-heteroarenes with azoalkenes generated in situ from α-halogeno hydrazones was developed under mild conditions.
Yu-Qing Guan +7 more
core +1 more source
Review of the Synthesis and Anticancer Properties of Pyrazolo[4,3-e][1,2,4]triazine Derivatives
Molecules, 2020 This review focuses on the cytotoxic effect of new synthetic pyrazolo[4,3-e][1,2,4]triazine derivatives against different tumor cell lines. Some annulated pyrazolotriazines i.e., pyrazolo[4,3-e][1,2,4]triazolo[4,3-b][1,2,4]triazines and pyrazolo[4,3-e ...
Zofia Bernat +4 more
doaj +1 more source
Synthesis and pharmacological evaluation of new fluorine substituted pyrimido[1,2-b][1,2,4]triazines and [1,3,5]-triazino-[1,2-b][1,2,4]triazines derived as CDK2 potential inhibitors [PDF]
, 2020 New fluorine-substituted polyfunctional pyrimido-[1,2-b]-[1,2,4]triazines and [1,3,5]-triazino[1,2-b]-[1,2,4]triazines were synthesized via the reaction between 3-amino-6-(2-aminophenyl)-1,2,4-triazin-5(2H)-one with polyfunctional oxygen/sulfur/nitrogen ...
Alotaibi, Fatimah, Bakhotmah, Dina
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Chemistry, 2023 A series of 2,4-disubstituted pyrrolo[2,1-f][1,2,4]triazines containing both aryl and thienyl substituents were synthesized by exploiting the 1,3-cycloaddition reaction of N(1)-ethyl-1,2,4-triazinium tetrafluoroborates with dimethyl ...
Nataliya N. Mochulskaya +9 more
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