Results 91 to 100 of about 2,851 (224)

Synthesis and physical-chemical properties of some 5-(3-fluorophenyl)-4-methyl-1,2,4-triazole-3-thiol derivatives

Фармацевтичний журнал, 2018
There are engaged scientists practically from all over the world to the 1,2,4-triazole system research but the greatest attention deserve the achievements of domestic scientists who managed from the very beginning to register new original medicines in ...
O. A. Bihdan, V. V. Parchenko
doaj   +1 more source

New Insights into 1,2,4-Triazole-3-Thiol Chemistry: Synthesis and Tuberculostatic Activity

International Journal of Environmental Sciences
Background: Tuberculosis (TB), a formidable global health crisis, relentlessly claims countless lives annually, perpetuating widespread morbidity and mortality. The dire need for groundbreaking treatments has ignited fervent research into innovative therapeutic paradigms. Materials and Methods: This pioneering study embarked on synthesizing an array of
Pooja Koganole, Pooja Gouda, Sushmita Hiremath, Sagar Shiraguppi, Suresh Honnalli, Pradeepkumar M. Ronad, Sanket Hosamani   +6 more
openaire   +1 more source

Application of Surface‐Enhanced Raman Spectroscopy (SERS) in Histamine Analysis of Aquatic Products: Principles, Applications, Challenges, and Prospects

Food Frontiers, Volume 6, Issue 6, Page 2698-2719, November 2025.
This review introduces the significant advantages of SERS detection of histamine, which is accurate, non‐destructive, and fast. By critically analyzing the current challenges, we propose future directions for industrializing the application of SERS in histamine detection.
Xingying Jiang, Ruizhi Yang, Jia Liang, Bin Zheng, Meiling Chen, Bin Zhang, Tao Han, Yadong Zhao, Soottawat Benjakul   +8 more
wiley   +1 more source

Spectroscopic and DFT studies of 3-(m-nitrophenyl)-4-allyl-5-mercapto-1,2,4-triazole and 3-furyl-4-allyl-5-mercapto-1,2,4-triazole

Next Materials
In this study, the synthesized derivatives of 1,2,4-triazoles, 3-(m-nitrophenyl)-4-allyl-5-mercapto-1,2,4-triazole and 3-furyl-4-allyl-5-mercapto-1,2,4-triazole, were characterized using NMR, FTIR, Raman, and UV-Vis spectroscopies. A theoretical study of
Liana Gabrielyan, Karine Grigoryan, Hasmik Shilajyan, Melanya Samvelyan, Gevorg Grigoryan, Tariel Ghochikyan   +5 more
doaj   +1 more source

Electrochemical and Theoretical Investigation of Triazole Derivatives as Corrosion Inhibitors for Copper in 3.5% NaCl Solution

International Journal of Electrochemical Science, 2013
This paper presents the investigation of 4-amino-5-phenyl-4H-1,2,4- triazole-3-thiol and 4-amino-5-nitrophenyl-4H-1,2,4-triazole-3-thiol as corrosion inhibitors for copper in 3.5% NaCl solution. Determinations of weight loss, electrochemical measurements,
Huiwen Tian, Weihua Li, Baorong Hou
doaj   +1 more source

The synthesis of 3-methyl-6-R-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives

Журнал органічної та фармацевтичної хімії, 2020
Aim. To conduct the synthesis and confirm the structure of 3-methyl-6-R-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole derivatives as potential biologically active compounds. Results and discussion. It has been shown that the heterocyclization reaction of 4-
Tetiana V. Hlazunova, Olexandr I. Panasenko, Yevhen G. Knysh   +2 more
doaj   +1 more source

Synthesis, Characterization, and Bioactivity of Quinoxaline Thiazolotriazoles

Journal of Heterocyclic Chemistry, Volume 62, Issue 11, Page 1698-1707, November 2025.
Quinoxaline thiazolotriazole target molecules with antibacterial, antitubercular and antidiabetic activity. ABSTRACT A total of 10 quinoxaline thiazolo[2,3‐c][1,2,4]triazole hybrid molecules were synthesized in a four‐step synthetic protocol. Six of these compounds are reported here for the first time.
Silungile Mhlongo, Sibusiso Senzani, Shahidul Islam, Kolawole Olofinsan, Moganavelli Singh, Nirasha Nundkumar, Sithabile Mokoena, Rajshekhar Karpoormath, Neil A. Koorbanally   +8 more
wiley   +1 more source

Amidine Syntheses from Classic to Contemporary for Medicinal Lead Compounds and Natural Products

European Journal of Organic Chemistry, Volume 28, Issue 40, October 29, 2025.
A revolution is underway in the synthesis of amidines with new methods unlocking complex, highly substituted amidines or closely related derivatives such as N‐sulfonyl amidines. This review surveys recent advances in amidines and related compounds, including methods to install them and bioactive molecules prominently featuring the amidine functionality.
Wyatt R. Swift‐Ramirez, Gregory A. Weiss   +1 more
wiley   +1 more source

Recent advances on MOF‐based colorimetric sensors

Bulletin of the Korean Chemical Society, Volume 46, Issue 10, Page 918-939, October 2025.
MOF‐based colorimetric sensors are widely explored due to their operational simplicity and outstanding structural tunability. In this review, the recent progress of MOF‐based colorimetric sensors is discussed, focusing on the role of MOFs in chromogenic transduction pathways.
Solmin Lee, Hyejin Yoo, Jin Yeong Kim
wiley   +1 more source

Synthesis of ylidene derivatives of 4-amino-5-(4-tert-butylphenyl)-4H-1,2,4-triazole-3-thiol

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2015
Aim. Modern medicine widely applies drugs from the group of 1,2,4-triazole (fluconazole, triazolam, alprazolam, letrozole and others) in the practice.
I. I. Aksionova, O. I. Panasenko, E. G. Knysh   +2 more
doaj   +1 more source