Results 101 to 110 of about 2,851 (224)

5-Furan-2yl[1,3,4]oxadiazole-2-thiol, 5-Furan-2yl-4H [1,2,4] triazole-3-thiol and Their Thiol-Thione Tautomerism

Molecules, 2005
5-Furan-2-yl[1,3,4]oxadiazole-2-thiol (Ia) and 5-furan-2-yl-4H-[1,2,4]-triazole-3-thiol (Ib) were synthesized from furan-2-carboxylic acid hydrazide. Mannich basesand methyl derivatives were then prepared.
A. Cansız, A. Çetin, M. Koparır   +2 more
doaj   +1 more source

Synthesis, Characterization, Molecular Docking Studies and Pharmaceutical Evaluation of some Novel [1,2,4]Triazolo[3,4-B][1,3,4]Thiadiazole [PDF]

A new series of fused [1,2,4]Triazolo[3,4-b][1,3,4]thiadiazole 4a-4e have been synthesized by many steps. Firstly, benzohydrazide [1] has been synthesized from the reaction of methyl benzoate with hydrazine hydrate.
Hamed, Fadil M., Hassan, Bassam A., Mekky, Athraa Hameed   +2 more
core   +2 more sources

Synthesis and biological activities of 3,6-disubstituted-1,2,4-triazolo-1,3,4- thiadiazole derivatives [PDF]

, 2018
Twelve novel triazolothiadiazole derivatives were synthesized from 4-amino-5-substituted-4H-1,2,4-triazole-3-thiols with various aromatic carboxylic acids by cyclization in the presence of phosphorous oxychloride. All the newly synthesized compounds were
H. Wei, X., J. Hu, Y., J. Wang, D., Lin, L., Liu, H.   +4 more
core   +2 more sources

The Effect of 1,2,4-Triazole-3-thiol Derivatives Bearing Hydrazone Moiety on Cancer Cell Migration and Growth of Melanoma, Breast, and Pancreatic Cancer Spheroids. [PDF]

Pharmaceuticals (Basel), 2022
Šermukšnytė A, Kantminienė K, Jonuškienė I, Tumosienė I, Petrikaitė V.   +4 more
europepmc   +1 more source

Elevated APOBEC3B Correlates with Poor Outcomes for Estrogen-Receptor-Positive Breast Cancers [PDF]

, 2014
Recent observations connected DNA cytosine deaminase APOBEC3B to the genetic evolution of breast cancer. We addressed whether APOBEC3B is associated with breast cancer clinical outcomes.
Burns, Michael B., Foekens, John A., Gelder, Marion E. Meijer-Van, Gray, Kathryn P., Harris, Reuben S., Heideman, Marinus R., Jacobs, Heinz, Leyland-Jones, Brian, Look, Maxime P., Martens, John W. M., Schlicker, Andreas, Sieuwerts, Anieta M., Wessels, Lodewyk, Willis, Scooter   +13 more
core   +3 more sources

Synthesis and Biological Properties of Novel Triazole-Thiol and Thiadiazole Derivatives of the 1,2,4-Triazole-3(5)-one Class

Molecules, 2014
2,2'-(4,4'(Butane-1,4-diyl/hexane-1,6-diyl)bis(3-methyl-5-oxo-4,5-dihydro-1,2,4- triazole-4,1-diyl)) diacetohydrazides 3a,b were obtained via the formation of diethyl 2,2'-(4,4'(butane-1,4-diyl/hexane-1,6-diyl)bis(3-methyl-5-oxo-4,5-dihydro-1,2,4 ...
Esra Düğdü, Yasemin Ünver, Dilek Ünlüer, Kemal Sancak   +3 more
doaj   +1 more source

Synthesis of novel 1,3‐substituted 1H‐[1,2,4]‐triazole‐3‐thiol derivatives

Heteroatom Chemistry, 2009
AbstractBy means of regioselective S‐alkylation of 1H‐1,2,4‐triazole‐3‐thiol (1), a series of S‐substituted derivatives 2a‐j were synthesized. In certain conditions, the reaction of 2 with arylsulfochlorides, arylisocyanates, and quaternary ammonium salts of azines corresponding compounds were obtained 1‐arylsulfonyl‐ (3a‐d), 1‐arylcarbonamido‐ (4a,b),
Karine A. Eliazyan, Lusya V. Shahbazyan, Vergine A. Pivazyan, Emma A. Ghazaryan, Aleksandr P. Yengoyan   +4 more
openaire   +1 more source

Prediction of biological activity of 4-(3,4 dimethoxybenzylidene)amino)-5-(2-fluorophenyl)-4H-1,2,4 triazole-3-thiol

Науковий вісник Львівського національного університету ветеринарної медицини та біотехнологій імені С.З. Ґжицького: Серія Ветеринарні науки
Among the various heterocyclic systems, 1,2,4-triazole derivatives occupy a leading position due to a whole range of unique and valuable properties.
V. P. Martynyshyn, V. M. Hunchak, B. V. Gutyj, O. P. Rudenko   +3 more
doaj   +1 more source

Synthesis, structure and properties of N-R-amides and hydrazides of 2-[4-R-5-(theophylline-7ʹ-yl)-1,2,4-triazole-3-ylthio]acetic acid

Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2017
One of the most important tasks of modern pharmaceutical science is the search for new biologically active substances, which have high efficacy and low toxicity.
A. S. Gotsulya
doaj   +1 more source

1,2,4-Triazole-3-thiol-protected silver-nanoparticles as a platform for ECE electrochemical reaction

Electrochemistry Communications, 2017
Abstract Incorporation of “green chemistry” principles into nanotechnology has become one of the key subjects for nanoscience researches. In this work, we report an electrochemical reaction with ECE mechanism on the surface of 1,2,4-triazole-3-thiol-protected silver nanoparticles (TATAgNPs) via electrochemical oxidation of catechol in the presence ...
Hamid Salehzadeh, Davood Nematollahi, Ali Hajian   +2 more
openaire   +1 more source