Results 21 to 30 of about 2,851 (224)
Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo
Typically, the system is already known are used as the core for a new substance, which have already proved themselves as potential drugs. So one of these is 1,2,4-triazole ring.
A. A. Safonov
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The aim of work is the investigation of properties of 2-((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-yl)thio)-1-arylethanones and 2((5-(3-,4-fluorophenyl)-4-R2-1,2,4-triazol-3-yl)thio)-1-arylethanols using modern physical-chemical methods.Materials and ...
O. A. Bihdan
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Four novel diazole-thiol derivatives namely: 5-(1-amino-2-sulfanylethyl)-1,3,4-oxadiazole-2(3H)-thione 6, 4-amino-5-(1-amino-2-sulfanylethyl)-4H-1,2,4-triazole-3-thiol 7, 1-amino-3-(1-amino-2-sulfanylethyl)-1H-1,2,4-triazole-5-thiol 8, and 5-(1-amino-2 ...
Mouna Souad Abbassi +3 more
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Synthesis and crystal structure of ethyl 2-{5-[2-(2,6-dichlorophenylamino)benzyl]-4-p-tolyl-4H-1,2,4-triazol-3-ylthio}acetate [PDF]
The compound 2-{5-[2-(2,6-dichlorophenylamino)benzyl]-4-p-tolyl-4H-1,2,4-triazol-3-ylthio}acetate has been prepared and characterized by IR, 1H NMR, 13C NMR and mass spectra. The crystal and molecular structure were further confirmed using single crystal
Gurubasavaraj, V.P. +2 more
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Physical-chemical properties of 5-(3-fluorophenyl)-4-amino-1,2,4-triazole-3-thiol s-derivatives
Introduction. Currently an attempt to combine 1,2,4-triazole heterocycle with various pharmacologically active fragments of other organic molecules is popular among the scientists.
O. A. Bihdan, V. V. Parchenko
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Synthesis of a Novel 2-((4,5-Diphenyl-4H-1,2,4-triazol-3-yl)thio)acetaldehyde as a Bisulfite Adduct
The scope of the current work was to synthesize an S-alkylated 1,2,4-triazole-3-thiol derivative. Synthesis was carried out in two steps: in the first step, 4,5-diphenyl-4H-1,2,4-triazole-3-thiol was S-alkylated using a halogenated acetal and cesium ...
Beniamin-Nicolae Pintea +3 more
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Anti-Tumor Activity of a Novel HS-Mimetic-Vascular Endothelial Growth Factor Binding Small Molecule [PDF]
The angiogenic process is controlled by variety of factors of which the vascular endothelial growth factor (VEGF) pathway plays a major role. A series of heparan sulfate mimetic small molecules targeting VEGF/VEGFR pathway has been synthesized.
Basappa, . +3 more
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The corrosion inhibition of steel in 1.0 M H2SO4 by some triazole derivatives namely, 4-amino-1,2,4-triazole-3-thiol (ATT), 4-amino-5-methyl-1,2,4-triazole-3-thiol (AMTT) and 4-amino-5-ethyl-1,2,4-triazole-3-thiol (AETT) has been studied using ...
Y.H. Ahmad, A.S. Mogoda, A.G. Gadallh
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Current and emerging therapeutic strategies for preventing inflammation and aggrecanase-mediated cartilage destruction in arthritis [PDF]
Arthritis is a multifactorial disease for which current therapeutic intervention with high efficacy remains challenging. Arthritis predominately affects articular joints, and cartilage deterioration and inflammation are key characteristics.
Dancevic,CM, McCulloch,DR
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Background:: Tuberculosis (TB) is caused by Mycobacterium tuberculosis and is one of the most contagious and fatal human pathogens which necessitates the development of modified existing drugs or derivatives with action against novel targets. Aims and Objectives:: In the present work, we have explored a few, 2-(5-(substituted)-4H-1,2,4-triazole-2 ...
Trupti Chitre +6 more
openaire +1 more source

