Results 31 to 40 of about 84,221 (197)
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016 Aim. To study the effect of 4-benzylideneamino-5-phenyl-4H-1,2,4-triazole-3-thiones and salts of 2-(4-amino-5-phenyl-4H-1,2,4-triazole-3-yltio)acetic acid on central component of nociceptive system on condition of thermal stimulation of limbs of rats ...
Ye. S. Pruhlo
doaj +1 more source
An insight on medicinal attributes of 1,2,4-triazoles
European Journal of Medicinal Chemistry, 2020 The present review aims to summarize the pharmacological profile of 1,2,4-triazole, one of the emerging privileged scaffold, as antifungal, antibacterial, anticancer, anticonvulsant, antituberculosis, antiviral, antiparasitic, analgesic and anti-inflammatory agents, etc. along with structure-activity relationship.
Garima Sumran +2 more
openaire +3 more sources
Synthesis and Antimicrobial Activity of 1,2,4‐Triazoles. [PDF]
ChemInform, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
K. R. Desai, K. D. Patel, B. D. Mistry
openaire +2 more sources
Pharmacological aspects of application of 1,2,4-triazole-3-thiol furan derivatives
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2016 Introduction. Nowadays 1,2,4-triazole-3-thiol furan derivatives have established themselves as a separate class of promising bioactive compounds. Presented substance is practically non-toxic and exhibits various kinds of pharmacological activity.
O. A. Bihdan +3 more
doaj +1 more source
4-(1,2,4-Triazol-1-yl)aniline [PDF]
Acta Crystallographica Section E Structure Reports Online, 2010 En el compuesto del título, C(8)H(8)N(4), el ángulo diedro entre el anillo de triazol [desviación máxima = 0.003 (1) Å] y el anillo de benceno es 34.57 (7) °. En el cristal, las mol-éculas están unidas en láminas que se encuentran paralelas al plano de CA a través de enlaces de hidrógeno N-H N y C-H N intermoleculares.
Hoong‐Kun Fun +4 more
openaire +3 more sources
CHIMIA, 1981 With the addition of 1,2,4-triazole or imidazole to aqueous solutions 0.1 M in glycine and 0.1 M in trimetaphosphate at room temperature, pH range 6.7-8.9, the yield of triglycine is improved by a factor of 10 to 20; the best yields are obtained with 1 ...
J. Rabinowitz, A. Hampai
doaj +1 more source
Synthesis methods of 1,2,4-triazole-3-thiones: review
Aktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki1,2,4-Triazole-containing compounds are unique heterocyclic compounds present in an array of pharmaceuticals and biologically important compounds used in drug-discovery studies against cancer cells, microbes, and various types of diseases in the human ...
Yu. S. Frolova +3 more
doaj +1 more source
Study acute toxicity of 4-(R-amino)-5-(thiophen-2-ylmethyl)-4H-1,2,4-triazole-3-thiol in vivo
Фармацевтичний журнал, 2018 Typically, the system is already known are used as the core for a new substance, which have already proved themselves as potential drugs. So one of these is 1,2,4-triazole ring.
A. A. Safonov
doaj +1 more source
Die Tautomerie des 1,2,4-Triazols
CHIMIA, 1967 The tautomeric constant of 1,2,4-triazole has been estimated from potentiometrically determined ionization constants of 1- and 4-alkyl-1,2,4-triazoles. The tautomeric ratio of (1H)- to (4H)-1,2,4-triazole is about 5–10:1.
Carl-Friedrich Kröger, Walter Freiberg
openaire +2 more sources
Thermal Rearrangement of Allyl Substituted Unsymmetric 4H-1,2,4-Triazoles to the Corresponding 1H-1,2,4-triazoles [PDF]
Molecules, 2001 A series of neat 4-(2-alkenyl) substituted 5-methyl-3-phenyl-4H-1,2,4-triazoles were thermolyzed at 320 oC producing a rearrangement products, of which the regioisomeric 1- and 2-substituted triazoles were the main products. The group migrations were rationalized in terms of consecutive SN2-type reactions. This mechanism was supported by a study of the
Jørgensen, Kåre B. +2 more
openaire +3 more sources